ZGPAT Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 200-1000 WB positive control: Human fetal liver tissue, LO2 cell, PC-3 cell, HEPG2 cell lysates IHC: 50-300 Positive control: Human ovarian cancer Predicted cell location: Nucleus |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein of human ZGPAT |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C. |
Stability | 1 year |
Predicted Protein Size | 57 kDa |
Database Link | |
Background | Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.