Germany
Japan
United Kingdom
China
ARFBP1 (HUWE1) Rabbit Polyclonal Antibody
Product Images
Other products for "HUWE1"
Specifications
| Product Data | |
| Applications | IHC |
| Recommended Dilution | IHC: 10-50 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm and Nucleus |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human HUWE1 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. |
| Stability | 1 year |
| Gene Name | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| Database Link | |
| Background | This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation. |
| Synonyms | ARF-BP1; HectH9; HSPC272; Ib772; KIAA0312; KIAA1578; LASU1; Mule; OTTHUMP00000023356; URE-B1; UREB1 |
| Reference Data | |
Documents
| Product Manuals |
| FAQs |
| SDS |
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.