CD30 (TNFRSF8) Mouse Monoclonal Antibody [Clone ID: FC-K3]

CAT#: TA383929

CD30 Mouse monoclonal Antibody

Specifications

Product Data

• Clone Name: FC-K3
• Applications: FC
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: A synthesized peptide derived from human CD30
• Formulation: 0.01M PBS, pH 7.4, 0.2%(w/v) BSA, 0.09%(w/v) NaN3
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C. Avoid freeze/thaw cycles.
• Stability: 1 year
• Gene Name: tumor necrosis factor receptor superfamily member 8
• Database Link:
  Entrez Gene 943 Human
  UniProt ID P28908
• Background: Swiss-Prot Acc.P28908.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
• Synonyms: CD30; D1S166E; KI-1