HDAC8 Rabbit Monoclonal Antibody [Clone ID: R03-4G9]

CAT#: TA384404

HDAC8 Rabbit monoclonal Antibody

Product Images

Western blot detection of HDAC8 in K562 cell lysates using HDAC8 Rabbit mAb(1:1000 diluted).Predicted band size:42kDa.Observed band size:42kDa.

Specifications

Product Data

• Clone Name: R03-4G9
• Applications: IP, WB
• Recommended Dilution: WB: 1/2000-1/10000
  IP: 1/20
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human HDAC8
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 42 kDa; Observed MW: 42 kDa
• Gene Name: histone deacetylase 8
• Database Link:
  Entrez Gene 55869 Human
  UniProt ID Q9BY41
• Background: Swiss-Prot Acc.Q9BY41.Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.
• Synonyms: CDA07; HD8; HDACL1; RPD3