H2BC21 Mouse Monoclonal Antibody [Clone ID: 7E2-2A1-8D2]

CAT#: TA384418

Histone H2B (7E2) Mouse monoclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded human breast caricnoma using Histone H2B Mouse mAb diluted at 1:500.

• 

  Western blot detection of Histone H2B in Hela and COS7 cell lysates using Histone H2B mouse mAb (1:100000 diluted).Predicted band size:14kDa.Observed band size:14kDa.

Specifications

Product Data

• Clone Name: 7E2-2A1-8D2
• Applications: IHC, WB
• Recommended Dilution: WB: 1/1000-3000
  IHC: 1/100-200
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic Peptide of Histone H2B
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Observed MW (kDa):14
• Gene Name: histone cluster 2, H2be
• Database Link:
  Entrez Gene 8349 Human
  UniProt ID P33778
• Background: Swiss-Prot Acc.P33778.Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
• Synonyms: GL105; H2B; H2B-GL105; H2B.1; H2B.q; H2B/q; H2BFQ; H2BGL105; H2BQ; MGC119802; MGC119804; MGC129733; MGC129734