MEKK2 (MAP3K2) Rabbit Polyclonal Antibody

CAT#: TA384713

MEKK2 Rabbit polyclonal Antibody

Specifications

Product Data

• Applications: FC, IF, IHC, IP, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
  IP: 1/30
  FC: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human MEKK2
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 70kDa
• Gene Name: mitogen-activated protein kinase kinase kinase 2
• Database Link:
  Entrez Gene 10746 Human
  UniProt ID Q9Y2U5
• Background: Swiss-Prot Acc.Q9Y2U5.The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates the kinases involved in the MAP kinase signaling pathway including MAPK7 and MAP2K4. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases (IKKs), and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2 (PRKCL2/PRK2), which suggests its involvement in PRKCL2 regulated signaling process.
• Synonyms: MAPKKK2; MEKK2; MEKK2B; OTTHUMP00000203817