NFATC1 Rabbit Monoclonal Antibody [Clone ID: R03-6I1]

CAT#: TA384857

Phospho-NFAT2 (Ser237) Rabbit monoclonal Antibody

Specifications

Product Data

• Clone Name: R03-6I1
• Applications: WB
• Recommended Dilution: WB: 1/1000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser237 of human NFAT2 (Phosphorylated)
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 101 kDa; Observed MW: 101 kDa
• Database Link:
  UniProt ID O95644
• Background: Swiss-Prot Acc.O95644.Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (PubMed:10358178). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function .