IKB beta (NFKBIB) Rabbit Monoclonal Antibody [Clone ID: R02-3C1]

CAT#: TA384870

IKB beta Rabbit monoclonal Antibody

Specifications

Product Data

• Clone Name: R02-3C1
• Applications: IHC, IP, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/50
  IP: 1/20
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human IKB beta
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 38 kDa; Observed MW: 48 kDa
• Gene Name: NFKB inhibitor beta
• Database Link:
  Entrez Gene 4793 Human
  UniProt ID Q15653
• Background: Swiss-Prot Acc.Q15653.Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
• Synonyms: I-kappa-B-beta; IkappaBbeta; IkB-B; IkB-beta; IKBB; NF-kappa-BIB; TRIP-9; TRIP9