PTCH1 Rabbit Polyclonal Antibody

CAT#: TA385073

PTCH1 Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded Human testis. 1, Antibody was diluted at 1:100(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

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  Immunohistochemical analysis of paraffin-embedded Human testis. 1, Antibody was diluted at 1:100(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

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  Immunohistochemical analysis of paraffin-embedded Human testis. 1, Antibody was diluted at 1:1(4°,overnight). 2, High-pressure and temperature EDTA, pH8. was used for antigen retrieval. 3,Secondary antibody was diluted at 1:2(room temperature, 3min).

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  Immunohistochemical analysis of paraffin-embedded Human Right kidney. 1, Antibody was diluted at 1:100(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

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  Immunohistochemical analysis of paraffin-embedded Human Right kidney. 1, Antibody was diluted at 1:100(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

• 

  Immunohistochemical analysis of paraffin-embedded Human Right kidney. 1, Antibody was diluted at 1:100(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

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Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/100-1/300
  ELISA: 1/10000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized peptide derived from human Patched. AA range:1-50
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Observed MW (kDa):160
• Gene Name: patched 1
• Database Link:
  Entrez Gene 5727 Human
  UniProt ID Q13635
• Background: Swiss-Prot Acc.Q13635.Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
• Synonyms: BCNS; FLJ26746; FLJ42602; HPE7; NBCCS; OTTHUMP00000021709; OTTHUMP00000021710; patched; PTC; PTC1; PTCH; PTCH11