MSK1 (RPS6KA5) Rabbit Polyclonal Antibody

CAT#: TA385187

Phospho-MSK1 (Ser376) Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded human lung cancer, using Phospho-MSK1 (S376) Antibody.

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  Western blot analysis of Phospho-MSK1 (S376) expression in HEK293 cell lysate treated with EGF.

Specifications

Product Data

• Applications: IF, IHC, IP, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
  IP: 1/50
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human Phospho-MSK1 (S376) (Phosphorylated)
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 90kDa
• Gene Name: ribosomal protein S6 kinase A5
• Database Link:
  Entrez Gene 9252 Human
  UniProt ID O75582
• Background: Swiss-Prot Acc.O75582.Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin.
• Synonyms: MGC1911; MSK1; MSPK1; RLPK; RSKL