VDAC1 Rabbit Polyclonal Antibody

CAT#: TA385545

VDAC1 Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded human liver, using VDAC1 Antibody.

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  Western blot analysis of Calreticulin expression in (1) HepG2 cell lysate; (2) Jurkat cell lysate.

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  Western blot analysis of VDAC1 expression in C2C12,THP-1,3T3,Jurakt and Hela cell lysates using VDAC1 antibody at 1/1 dilution.Predicted band size:31KDa.Observed band size:31KDa.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human VDAC1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 31kDa
• Gene Name: voltage dependent anion channel 1
• Database Link:
  Entrez Gene 7416 Human
  UniProt ID P21796
• Background: Swiss-Prot Acc.P21796.Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria. In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics.
• Synonyms: hVDAC1; MGC111064; OTTHUMP00000159381; OTTHUMP00000165946; PORIN; PORIN-31-HL; VDAC; VDAC-1