RBM15 Rabbit Polyclonal Antibody

CAT#: TA590462

Rabbit Polyclonal RBM15 Antibody

Product Images

Western Blot: RBM15 Antibody - Samples: Lane 1: Marker: 250, 130, 95, 72, 55, 36, 28, 17, 11 / Lane 2: RT-4 / Lane 3: U-251MG sp / Lane 4: Human Plasma / Lane 5: Liver / Lane 6: Tonsil; Target weight: 107, 106, 3 (splice variants)

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  ELISA: RBM15 Antibody - Affinity Purified

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  Immunohistochemistry: RBM15 Antibody - A majority of normal and malignant tissues showed moderate to strong nuclear and moderate cytoplasmic staining. In normal tissues, strongest positivity was found in gastro-intestinal glandular cells and in neuronal cells of the CNS. Prostate, bile duct cells and ovarian stromal cells were negative. Malignant tissues stained similarly, with strongest immunoreactivity found in colo-rectal cancers and malignant gliomas. Other tumors generally displayed moderate nuclear and cytoplasmic staining. Most prostate cancers were negative. Image and statement courtesy of the Human Protein Atlas (HPA).

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 1:5000-1:20000; ELISA: 1:100-1:2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DNA immunization. This antibody is specific for the Middle Region of the target protein.
• Formulation: 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
• Concentration: 1.1mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: RNA binding motif protein 15
• Database Link:
  NP_073605
  Entrez Gene 64783 Human
  UniProt ID Q96T37
• Background: Members of the SPEN (Split-end) family of proteins, including RBM15, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]). [supplied by OMIM]
• Synonyms: OTT; OTT1; SPEN
• Note: This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

• Protein Families: Transcription Factors