Human PEDF (SERPINF1) ELISA KIT (1 x 96 wells)
CAT#: EA102235
For quantitative detection of human PEDF in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
USD 470.00
3 Weeks*
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Specifications
Product Data | |
Format | 8x12 divisible strips |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Human PEDF |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 0.78ng/ml-50ng/ml |
Specificity | This kit is used for quantitative detection of Human PEDF |
Sensitivity | <20pg/ml |
Reactivities | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Components |
|
Background | Pigment epithelium-derived factor (PEDF) is also known as serpin F1 (SERPINF1). In humans, it is encoded by the SERPINF1 gene. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. It suppresses retinal neovascularization and endothelial cell proliferation. And Antiangiogenic function is also conferred by PEDF through inhibition of both VEGFR-1 and VEGFR-2. In addition, the antitumorigenic effects of PEDF are not only due to inhibition of supporting vasculature, but also due to effects on the cancer cells themselves. PEDF is shown to inhibit cancer cell proliferation and increase apoptosis via the FAS/FASL pathway. Expression of PEDF in the human retina is found at 7.4 weeks of gestation, suggesting it may play a role in retinal neuron differentiation. |
Gene Symbol | SERPINF1 |
Standard Curve |
Human PEDF/SerpinF1 ELISA Kit standard curve
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.