PLAUR (NM_001005376) Human 3' UTR Clone
CAT#: SC204851
3`UTR clone of plasminogen activator urokinase receptor (PLAUR) transcript variant 2 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | PLAUR |
Synonyms | CD87; U-PAR; UPAR; URKR |
ACCN | NM_001005376 |
Insert Size | 366 bp |
Sequence Data |
>SC204851 3'UTR clone of NM_001005376
The sequence shown below is from the reference sequence of NM_001005376. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC ATGCTGTGAGGAAGCCCAAGCTACTCATGTATAAATGCCATGTGGAGATAGAGCCCCAGATGTTTCAGCC ATCTCAGCCCAGGCACCAGACAAGTGGGTGAAGAAGCCACCTTGGACATGTAGCCCCAGCAGATGTGATA TAGAGAAGAAACAGGAAACTTGGCTATATTAGTTTCCTAGGGCTGCCTGTGATAAATTATTACAAACTTT ATAAACTAACACATTGTGTGCCTATATCAAAACATCATGGAAGGACAGGCACAGTGGCTCATGCCTGTAG TCCTAGCACTTTGGGAGGGTGAGAAAGGAAGATCTCTTGAGCTCAGGAGTTCAAGATCAGCCTGGGCAAC ACAGTGAGACCTCATC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_001005376.1 |
Summary | 'This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]' |
Locus ID | 5329 |
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