NKG2A (KLRC1) (NM_002259) Human 3' UTR Clone
CAT#: SC207081
3`UTR clone of killer cell lectin-like receptor subfamily C member 1 (KLRC1) transcript variant 1 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | KLRC1 |
Synonyms | CD159A; NKG2; NKG2A |
ACCN | NM_002259 |
Insert Size | 555 bp |
Sequence Data |
>SC207081 3'UTR clone of NM_002259
The sequence shown below is from the reference sequence of NM_002259. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC CCCAGTGTGGATCTTCAATAATATATCATTGTAAGCATAAGCTTTAGAGGTAAAGCGTTTGCATTTGCAG TGCATCAGATAAATTGTATATTTCTTAAAATAGAAATATATTATGATTGCATAAATCTTAAAATGAATTA TGTTATTTGCTCTAATAAGAAAATTCTAAATCAATTATTGAAACAGGATACACACAATTACTAAAGTACA GACATCCTAGCATTTGTGTCGGGCTCATTTTGCTCAACATGGTATTTGTGGTTTTCAGCCTTTCTAAAAG TTGCATGTTATGTGAGTCAGCTTATAGGAAGTACCAAGAACAGTCAAACCCATGGAGACAGAAAGTAGAA TAGTGGTTGCCAATGTCTGAGGGAGGTTGAAATAGGAGATGACCTCTAACTGATAGAACGTTACTTTGTG TCGTGATGAAAACTTTCTAAATTTCAGTAGTGGTGATGGTTGTAACTCTGCGAATATACTAAACATCATT GATTTTTAATCATTTTAAGTGCATGAAATGTATGCTTTGTACACGACACTTCAATAAAGCTATCC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_002259.4 |
Summary | 'Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015]' |
Locus ID | 3821 |
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