PKR (EIF2AK2) (NM_001135652) Human 3' UTR Clone
CAT#: SC209229
3`UTR clone of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) transcript variant 3 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | EIF2AK2 |
Synonyms | EIF2AK1; PKR; PPP1R83; PRKR |
ACCN | NM_001135652 |
Insert Size | 735 bp |
Sequence Data |
>SC209229 3'UTR clone of NM_001135652
The sequence shown below is from the reference sequence of NM_001135652. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC GTGTGGAAGAAAAGCCCAGAGAAAAATGAACGACACACATGTTAGAGCCCTTCTGAAAAAGTATCCTGCT TCTGATATGCAGTTTTCCTTAAATTATCTAAAATCTGCTAGGGAATATCAATAGATATTTACCTTTTATT TTAATGTTTCCTTTAATTTTTTACTATTTTTACTAATCTTTCTGCAGAAACAGAAAGGTTTTCTTCTTTT TGCTTCAAAAACATTCTTACATTTTACTTTTTCCTGGCTCATCTCTTTATTCTTTTTTTTTTTTTAAAGA CAGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGCAATGACACAGTCTTGGCTCACTGCAACTTCTGCCTCT TGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGATTACAGGCATGTGCCACCCACCCAAC TAATTTTTGTGTTTTTAATAAAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTC AAGTAATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGGATGAGCCACCGCGCCCAGCCTCAT CTCTTTGTTCTAAAGATGGAAAAACCACCCCCAAATTTTCTTTTTATACTATTAATGAATCAATCAATTC ATATCTATTTATTAAATTTCTACCGCTTTTAGGCCAAAAAAATGTAAGATCGTTCTCTGCCTCACATAGC TTACAAGCCAGCTGGAGAAATATGGTACTCATTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_001135652.1 |
Summary | 'The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]' |
Locus ID | 5610 |
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