RPTP mu (PTPRM) (NM_002845) Human 3' UTR Clone

CAT#: SC209279

3`UTR clone of protein tyrosine phosphatase receptor type M (PTPRM) transcript variant 2 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: PTPRM
• Synonyms: hR-PTPu; PTPRL1; R-PTP-MU; RPTPM; RPTPU
• ACCN: NM_002845
• Insert Size: 727 bp
• Sequence Data:
  Insert Sequence

  >SC209279 3'UTR clone of NM_002845
  The sequence shown below is from the reference sequence of NM_002845. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CAAGTTCTGCTACGAGGTGGCCCTGGAATACTTGAATTCTGGCTGATGGTGTAAACAGCTCTGCAAACAA
  TCCCTTTCATACCACAAAGCCAAGACGTTCCATGGTATTTGTGCAAAAGAGATGAAGACTTCTCAATATG
  CTTATTTTGCTTTGCATAATTGGCTCTTTTTAAGAGCCCAAGAAAGTGTTTCTAAAATTGCTTGCACTGC
  CCAATCCCAGTAATGCTGCTGCCTGACAGAAACACACACACAGCCACAGTTGCCAAATCCCGTACTCCTT
  GCCACCGGCTTCCTAGAGCAGCGTAGACAGCTGGTAAACTGAAGAGCACAACTATATTCTTATGAAGGAA
  TTTGTACCTTTGGGGTATTATTTTGTGGCCCGTGACCCTCGTTATTGTTACAGCTGAGTGTATGTTTTTG
  TTCTGTGGAGAATGCTATCTGGCATTATGGTAATATATTATTTTAGGTAATATTTGTACTTTAACATGTT
  GCATAATATATGCTTATGTAGCTTTCCAGGACTAACAGATAAATGTGTAATGAACAAAGATATGTTGTAT
  GAGTCGTCGTTTCTGTCAGATTTGTATTGTTTCCAAGGGAAAAGCTTGGGGGAGGACTCAGTTCACAAAA
  TGCAAAACTCAACGATCAGATTCACGGACCCAGAGCTTTTCCATGTGTTTATATTGTAAATATTTTTGAT
  TTCATCAAATTATTTATTCATTAAAAG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_002845.3
• Summary: 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008]'
• Locus ID: 5797