SUCLA2 (NM_003850) Human 3' UTR Clone

CAT#: SC209360

3`UTR clone of succinate-CoA ligase ADP-forming beta subunit (SUCLA2) nuclear gene encoding mitochondrial protein for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: SUCLA2
• Synonyms: A-BETA; A-SCS; MTDPS5; SCS-betaA
• ACCN: NM_003850
• Insert Size: 734
• Sequence Data:
  Insert Sequence

  >SC209360 3'UTR clone of NM_003850
  The sequence shown below is from the reference sequence of NM_003850. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  AGCGAAGCAAGCACATGTGGATGTGAAATTTCAGTTGCCAATATGATCTGAAAACCCAGTGGATGGCTGA
  AGGTGTTAAATGTGCTATAATCATTAAGAATACTGTGTTCTGTGTTATTGTTCTTTTTCTTTTTAGTGTG
  TGGAGATTGTAATTGCCATCTAGGCACACAAACATTTAAAAGGATTTGGACTGCATTTAATTGTACCATT
  CAGAATGGACTGTTTGTACGAAGCATGTATAATGCAGTTATCTTCTTTCTTTTGTCGCAGCCAGTCTTTT
  TTGCTTCTCCTACAAAACGTAACTTGCAATTTGCCAGTTTATTATTGTTGGATACAAAGTTCTTCATTGA
  TAAGAGTCCTATAAATAAGATAAATACGAAGATAAAGCTTTATTCTTTAGTGTTAAAATACAGTATATCT
  AATAACTAGCCTCATTAGTAGAGCAGTATATTAAAACAATGTTTTATGTAAAAAGTGTTTATCTTCAGCA
  CCAAATACATGATAAATGTATCAATCACTATTTATAAACAGAGCTTTCAAACACTCCTCAGAATATTCTT
  CTAAGTATTTTGATGAAGTAACTTTGTAATTATTTGAACATTGTTTTAATCATTAGGAAACACTGATTAA
  CTGCAAGTCTTCATGATTCTGTCATATTAAGAAACACCTGTAGGTTTGCTTCAAATAAAGGCATATATAC
  CAAGGACTTACAGACAAAATTAAGAATGTCAATT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_003850.2
• Summary: Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq, Jul 2008]
• Locus ID: 8803