5 HT 2A (HTR2A) (NM_001165947) Human 3' UTR Clone

CAT#: SC214692

3`UTR clone of 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) transcript variant 2 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: HTR2A
• Synonyms: 5-HT2A; HTR2
• ACCN: NM_001165947
• Insert Size: 1474 bp
• Sequence Data:
  Insert Sequence

  >SC214692 3'UTR clone of NM_001165947
  The sequence shown below is from the reference sequence of NM_001165947. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GACAATAGCGACGGAGTGAATGAAAAGGTGAGCTGTGTGTGATAGGCTAGTTGCCGTGGCAACTGTGGAA
  GGCACACTGAGCAAGTTTTCACCTATCTGGAAAAAAAAAAATATGAGATTGGAAAAAATTAGACAAGTCT
  AGTGGAACCAACGATCATATCTGTATGCCTCATTTTATTCTGTCAATGAAAAGCGGGGTTCAATGCTACA
  AAATGTGTGCTTGGAAAATGTTCTGACAGCATTTCAGCTGTGAGCTTTCTGATACTTATTTATAACATTG
  TAAATGATATGTCTTTAAAATGATTCACTTTTATTGTATAATTATGAAGCCCTAAGTAAATCTAAATTAA
  CTTCTATTTTCAAGTGGAAACCTTGCTGCTATGCTGTTCATTGATGACATGGGATTGAGTTGGTTACCTA
  TTGCTGTAAATAAAAATAGCTATAAATAGTGAAAATTTTATTGAATATAATGGCCTCTTAAAAATTATCT
  TTAAAACTTACTATGGTATATATTTTGAAAGGAGAAAAAAAAAGCCACTAAGGTCAGTGTTATAAAATCT
  GTATTGCTAAGATAATTAAATGAAATACTTGACAACATTTTTCATTCCTGCTTTTTCATAGATACCATTT
  TGAAATATTCACAAGGTTGCTGGCATTTGCTGCATTTCAAGTTAATTCTCAGAAGTGAAAAAGACTTCAA
  ATGTTATTCAATAACTATTGCTGCTTTCTCTTCTACTTCTTGTGCTTTACTCTGAATTTCCAGTGTGGTC
  TTGTTTAATATTTGTTCCTCTAGGTAAACTAGCAAAAGGATGATTTAACATTACCAAATGCCTTTCTAGC
  AATTGCTTCTCTAAAACAGCACTATCGAGGTATTTGGTAACTTGCTGTGAAATGACTGCATCATGCATGC
  ACTCTTTTGAGCAGTAAATGTATATTGATGTAACTGTGTCAGGATTGAGGATGAACTCAGGTTTCCGGCT
  ACTGACAGTGGTAGAGTCCTAGGACATCTCTGTAAAAAGCAGGTGACTTTCCTATGACACTCATCAGGTA
  AACTGATGCTTTCAGATCCATCGGTTTATACTATTTATTAAAACCATTCTGCTTGGTTCCACAATCATCT
  ATTGAGTGTACATTTATGTGTGAAGCAAATTTCTAGATATGAGAAATATAAAAATAATTAAAACAAAATC
  CTTGCCTTCAAACGAAATGGCTCGGCCAGGCACGGAGGCTCGTGCATGTAATCCTAGCACTTTGGGAGGC
  TGAGATGGGAGGATCACTTGAGGCCAAGAGTTTGAGACCAACCTGGGTAACAAAGTGAGACCTCCCTGTC
  TCTACAAAAAAAATCAAAAAATTATCTGATCCTTGTGGCACACAACTGTGGTCCCAGCTACAGGGGAGGC
  TGAGACGCAAGGATCACTTGAGCCCAGAAGCTCAAGGCTGCAGTGAGCCAAGTTCACACCACTGCCATTT
  CCTC
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_001165947.1
• Summary: 'This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]'
• Locus ID: 3356