IGF2R (NM_000876) Human 3' UTR Clone

CAT#: SC214752

3`UTR clone of insulin-like growth factor 2 receptor (IGF2R) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: IGF2R
• Synonyms: CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R; MPR1; MPR 300; MPR300; MPRI
• ACCN: NM_000876
• Insert Size: 1465 bp
• Sequence Data:
  Insert Sequence

  >SC214752 3'UTR clone of NM_000876
  The sequence shown below is from the reference sequence of NM_000876. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GGACCTCTTACACATCTGACTCCGCAGTGCCTGCAGGGGAGCACGGAGCCGCGGGACAGCCAAGCACCTC
  CAACCAAATAAGACTTCCACTCGATGATGCTTCTATAATTTTGCCTTTAACAGAAACTTTCAAAAGGGAA
  GAGTTTTTGTGATGGGGGAGAGGGTGAAGGAGGTCAGGCCCCACTCCTTCCTGATTGTTTACAGTCATTG
  GAATAAGGCATGGCTCAGATCGGCCACAGGGCGGTACCTTGTGCCCAGGGTTTTGCCCCAAGTCCTCATT
  TAAAAGCATAAGGCCGGACGCATCTCAAAACAGAGGGCTGCATTCGAAGAAACCCTTGCTGCTTTAGTCC
  CGATAGGGTATTTGACCCCGATATATTTTAGCATTTTAATTCTCTCCCCCTATTTATTGACTTTGACAAT
  TACTCAGGTTTGAGAAAAAGGAAAAAAAAACAGCCACCGTTTCTTCCTGCCAGCAGGGGTGTGATGTACC
  AGTTTGTCCATCTTGAGATGGTGAGGCTGTCAGTGTATGGGGCAGCTTCCGGCGGGATGTTGAACTGGTC
  ATTAATGTGTCCCCTGAGTTGGAGCTCATTCTGTCTCTTTTCTCTTTTGCTTTCTGTTTCTTAAGGGCAC
  ACACACGTGCGTGCGAGCACACACACACATACGTGCACAGGGTCCCCGAGTGCCTAGGTTTTGGAGAGTT
  TGCCTGTTCTATGCCTTTAGTCAGGAATGGCTGCACCTTTTTGCATGATATCTTCAAGCCTGGGCGTACA
  GAGCACATTTGTCAGTATTTTTGCCGGCTGGTGAATTCAAACAACCTGCCCAAAGATTGATTTGTGTGTT
  TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGAGTGGAGTTGAGGTGTCAGAGAAAATGAATTTTTTC
  CAGATTTGGGGTATAGGTCTCATCTCTTCAGGTTCTCATGATACCACCTTTACTGTGCTTATTTTTTTAA
  GAAAAAAGTGTTGATCAACCATTCGACCTATAAGAAGCCTTAATTTGCACAGTGTGTGACTTACAGAAAC
  TGCATGAAAAATCATGGGCCAGAGCCTCGGCCCTAGCATTGCACTTGGCCTCATGCTGGAGGGAGGCTGG
  GCGGGTACAGCGCGGAGGAGGAGGGAGGCCAGGCGGGCATGGCGTGGAGGAGGAGGGAGGCCGGGCGGTC
  ACAGCATGGAGGAGGAGGGAGGCGCTGCTGGTGTTCTTATTCTGGCGGCAGCGCCTTTCCTGCCATGTTT
  AGTGAATGACTTTTCTCGCATTGTAGAATTGTATATAGACTCTGGTGTTCTATTGCTGAGAAGCAAACCG
  CCCTGCAGCATCCCTCAGCCTGTACCGGTTTGGCTGGCTTGTTTGATTTCAACATGAGTGTATTTTTTAA
  AATTGATTTTTCTCTTCATTTTTTTTTCAATCAACTTTACTGTAATATAAAGTATTCAACAATTT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_000876.2
• Summary: 'This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]'
• Locus ID: 3482