LRRK2 (NM_198578) Human 3' UTR Clone

CAT#: SC215135

3`UTR clone of leucine-rich repeat kinase 2 (LRRK2) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: LRRK2
• Synonyms: AURA17; DARDARIN; PARK8; RIPK7; ROCO2
• ACCN: NM_198578
• Insert Size: 1528
• Sequence Data:
  Insert Sequence

  >SC215135 3'UTR clone of NM_198578
  The sequence shown below is from the reference sequence of NM_198578. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GACGAACATCTGTTGAGTAAGAGAGAAATAGGAATTGTCTTTGGATAGGAAAATTATTCTCTCCTCTTGT
  AAATATTTATTTTAAAAATGTTCACATGGAAAGGGTACTCACATTTTTTGAAATAGCTCGTGTGTATGAA
  GGAATGTTATTATTTTTAATTTAAATATATGTAAAAATACTTACCAGTAAATGTGTATTTTAAAGAACTA
  TTTAAAACACAATGTTATATTTCTTATAAATACCAGTTACTTTCGTTCATTAATTAATGAAAATAAATCT
  GTGAAGTACCTAATTTAAGTACTCATACTAAAATTTATAAGGCCGATAATTTTTTGTTTTCTTGTCTGTA
  ATGGAGGTAAACTTTATTTTAAATTCTGTGCTTAAGACAGGACTATTGCTTGTCGATTTTTCTAGAAATC
  TGCACGGTATAATGAAAATATTAAGACAGTTTCCCATGTAATGTATTCCTTCTTAGATTGCATCGAAATG
  CACTATCATATATGCTTGTAAATATTCAAATGAATTTGCACTAATAAAGTCCTTTGTTGGTATGTGAATT
  CTCTTTGTTGCTGTTGCAAACAGTGCATCTTACACAACTTCACTCAATTCAAAAGAAAACTCCATTAAAA
  GTACTAATGAAAAAACATGACATACTGTCAAAGTCCTCATATCTAGGAAAGACACAGAAACTCTCTTTGT
  CACAGAAACTCTCTGTGTCTTTCCTAGACATAATAGAGTTGTTTTTCAACTCTATGTTTGAATGTGGATA
  CCCTGAATTTTGTATAATTAGTGTAAATACAGTGTTCAGTCCTTCAAGTGATATTTTTATTTTTTTATTC
  ATACCACTAGCTACTTGTTTTCTAATCTGCTTCATTCTAATGCTTATATTCATCTTTTCCCTAAATTTGT
  GATGCTGCAGATCCTACATCATTCAGATAGAAACCTTTTTTTTTTTCAGAATTATAGAATTCCACAGCTC
  CTACCAAGACCATGAGGATAAATATCTAACACTTTTCAGTTGCTGAAGGAGAAAGGAGCTTTAGTTATGA
  TGGATAAAAATATCTGCCACCCTAGGCTTCCAAATTATACTTAAATTGTTTACATAGCTTACCACAATAG
  GAGTATCAGGGCCAAATACCTATGTAATAATTTGAGGTCATTTCTGCTTTAGGAAAAGTACTTTCGGTAA
  ATTCTTTGGCCCTGACCAGTATTCATTATTTCAGATAATTCCCTGTGATAGGACAACTAGTACATTTAAT
  ATTCTCAGAACTTATGGCATTTTACTATGTGAAAACTTTAAATTTATTTATATTAAGGGTAATCAAATTC
  TTAAAGATGAAAGATTTTCTGTATTTTAAAGGAAGCTATGCTTTAACTTGTTATGTAATTAACAAAAAAA
  TCATATATAATAGAGCTCTTTGTTCCAGTGTTATCTCTTTCATTGTTACTTTGTATTTGCAATTTTTTTT
  ACCAAAGACAAATTAAAAAAATGAATACCATATTTAAATGGAATAATAAAGGTTTTTT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_198578.3
• Summary: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]
• Locus ID: 120892