BACE1 (NM_012104) Human 3' UTR Clone

CAT#: SC221357

3`UTR clone of beta-site APP-cleaving enzyme 1 (BACE1) transcript variant a for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: BACE1
• Synonyms: ASP2; BACE; HSPC104
• ACCN: NM_012104
• Insert Size: 3866
• Sequence Data:
  Insert Sequence

  >SC221357 3'UTR clone of NM_012104
  The sequence shown below is from the reference sequence of NM_012104. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  TGCTGATGACATCTCCCTGCTGAAGTGAGGAGGCCCATGGGCAGAAGATAGAGATTCCCCTGGACCACAC
  CTCCGTGGTTCACTTTGGTCACAAGTAGGAGACACAGATGGCACCTGTGGCCAGAGCACCTCAGGACCCT
  CCCCACCCACCAAATGCCTCTGCCTTGATGGAGAAGGAAAAGGCTGGCAAGGTGGGTTCCAGGGACTGTA
  CCTGTAGGAAACAGAAAAGAGAAGAAAGAAGCACTCTGCTGGCGGGAATACTCTTGGTCACCTCAAATTT
  AAGTCGGGAAATTCTGCTGCTTGAAACTTCAGCCCTGAACCTTTGTCCACCATTCCTTTAAATTCTCCAA
  CCCAAAGTATTCTTCTTTTCTTAGTTTCAGAAGTACTGGCATCACACGCAGGTTACCTTGGCGTGTGTCC
  CTGTGGTACCCTGGCAGAGAAGAGACCAAGCTTGTTTCCCTGCTGGCCAAAGTCAGTAGGAGAGGATGCA
  CAGTTTGCTATTTGCTTTAGAGACAGGGACTGTATAAACAAGCCTAACATTGGTGCAAAGATTGCCTCTT
  GAATTAAAAAAAAAAACTAGATTGACTATTTATACAAATGGGGGCGGCTGGAAAGAGGAGAAGGAGAGGG
  AGTACAAAGACAGGGAATAGTGGGATCAAAGCTAGGAAAGGCAGAAACACAACCACTCACCAGTCCTAGT
  TTTAGACCTCATCTCCAAGATAGCATCCCATCTCAGAAGATGGGTGTTGTTTTCAATGTTTTCTTTTCTG
  TGGTTGCAGCCTGACCAAAAGTGAGATGGGAAGGGCTTATCTAGCCAAAGAGCTCTTTTTTAGCTCTCTT
  AAATGAAGTGCCCACTAAGAAGTTCCACTTAACACATGAATTTCTGCCATATTAATTTCATTGTCTCTAT
  CTGAACCACCCTTTATTCTACATATGATAGGCAGCACTGAAATATCCTAACCCCCTAAGCTCCAGGTGCC
  CTGTGGGAGAGCAACTGGACTATAGCAGGGCTGGGCTCTGTCTTCCTGGTCATAGGCTCACTCTTTCCCC
  CAAATCTTCCTCTGGAGCTTTGCAGCCAAGGTGCTAAAAGGAATAGGTAGGAGACCTCTTCTATCTAATC
  CTTAAAAGCATAATGTTGAACATTCATTCAACAGCTGATGCCCTATAACCCCTGCCTGGATTTCTTCCTA
  TTAGGCTATAAGAAGTAGCAAGATCTTTACATAATTCAGAGTGGTTTCATTGCCTTCCTACCCTCTCTAA
  TGGCCCCTCCATTTATTTGACTAAAGCATCACACAGTGGCACTAGCATTATACCAAGAGTATGAGAAATA
  CAGTGCTTTATGGCTCTAACATTACTGCCTTCAGTATCAAGGCTGCCTGGAGAAAGGATGGCAGCCTCAG
  GGCTTCCTTATGTCCTCCACCACAAGAGCTCCTTGATGAAGGTCATCTTTTTCCCCTATCCTGTTCTTCC
  CCTCCCCGCTCCTAATGGTACGTGGGTACCCAGGCTGGTTCTTGGGCTAGGTAGTGGGGACCAAGTTCAT
  TACCTCCCTATCAGTTCTAGCATAGTAAACTACGGTACCAGTGTTAGTGGGAAGAGCTGGGTTTTCCTAG
  TATACCCACTGCATCCTACTCCTACCTGGTCAACCCGCTGCTTCCAGGTATGGGACCTGCTAAGTGTGGA
  ATTACCTGATAAGGGAGAGGGAAATACAAGGAGGGCCTCTGGTGTTCCTGGCCTCAGCCAGCTGCCCACA
  AGCCATAAACCAATAAAACAAGAATACTGAGTCAGTTTTTTATCTGGGTTCTCTTCATTCCCACTGCACT
  TGGTGCTGCTTTGGCTGACTGGGAACACCCCATAACTACAGAGTCTGACAGGAAGACTGGAGACTGTCCA
  CTTCTAGCTCGGAACTTACTGTGTAAATAAACTTTCAGAACTGCTACCATGAAGTGAAAATGCCACATTT
  TGCTTTATAATTTCTACCCATGTTGGGAAAAACTGGCTTTTTCCCAGCCCTTTCCAGGGCATAAAACTCA
  ACCCCTTCGATAGCAAGTCCCATCAGCCTATTATTTTTTTAAAGAAAACTTGCACTTGTTTTTCTTTTTA
  CAGTTACTTCCTTCCTGCCCCAAAATTATAAACTCTAAGTGTAAAAAAAAGTCTTAACAACAGCTTCTTG
  CTTGTAAAAATATGTATTATACATCTGTATTTTTAAATTCTGCTCCTGAAAAATGACTGTCCCATTCTCC
  ACTCACTGCATTTGGGGCCTTTCCCATTGGTCTGCATGTCTTTTATCATTGCAGGCCAGTGGACAGAGGG
  AGAAGGGAGAACAGGGGTCGCCAACACTTGTGTTGCTTTCTGACTGATCCTGAACAAGAAAGAGTAACAC
  TGAGGCGCTCGCTCCCATGCACAACTCTCCAAAACACTTATCCTCCTGCAAGAGTGGGCTTTCCAGGGTC
  TTTACTGGGAAGCAGTTAAGCCCCCTCCTCACCCCTTCCTTTTTTCTTTCTTTACTCCTTTGGCTTCAAA
  GGATTTTGGAAAAGAAACAATATGCTTTACACTCATTTTCAATTTCTAAATTTGCAGGGGATACTGAAAA
  ATACGGCAGGTGGCCTAAGGCTGCTGTAAAGTTGAGGGGAGAGGAAATCTTAAGATTACAAGATAAAAAA
  CGAATCCCCTAAACAAAAAGAACAATAGAACTGGTCTTCCATTTTGCCACCTTTCCTGTTCATGACAGCT
  ACTAACCTGGAGACAGTAACATTTCATTAACCAAAGAAAGTGGGTCACCTGACCTCTGAAGAGCTGAGTA
  CTCAGGCCACTCCAATCACCCTACAAGATGCCAAGGAGGTCCCAGGAAGTCCAGCTCCTTAAACTGACGC
  TAGTCAATAAACCTGGGCAAGTGAGGCAAGAGAAATGAGGAAGAATCCATCTGTGAGGTGACAGGCAAGG
  ATGAAAGACAAAGAAGGAAAAGAGTATCAAAGGCAGAAAGGAGATCATTTAGTTGGGTCTGAAAGGAAAA
  GTCTTTGCTATCCGACATGTACTGCTAGTACCTGTAAGCATTTTAGGTCCCAGAATGGAAAAAAAAATCA
  GCTATTGGTAATATAATAATGTCCTTTCCCTGGAGTCAGTTTTTTTAAAAAGTTAACTCTTAGTTTTTAC
  TTGTTTAATTCTAAAAGAGAAGGGAGCTGAGGCCATTCCCTGTAGGAGTAAAGATAAAAGGATAGGAAAA
  GATTCAAAGCTCTAATAGAGTCACAGCTTTCCCAGGTATAAAACCTAAAATTAAGAAGTACAATAAGCAG
  AGGTGGAAAATGATCTAGTTCCTGATAGCTACCCACAGAGCAAGTGATTTATAAATTTGAAATCCAAACT
  ACTTTCTTAATATCACTTTGGTCTCCATTTTTCCCAGGACAGGAAATATGTCCCCCCCTAACTTTCTTGC
  TTCAAAAATTAAAATCCAGCATCCCAAGATCATTCTACAAGTAATTTTGCACAGACATCTCCTCACCCCA
  GTGCCTGTCTGGAGCTCACCCAAGGTCACCAAACAACTTGGTTGTGAACCAACTGCCTTAACCTTCTGGG
  GGAGGGGGATTAGCTAGACTAGGAGACCAGAAGTGAATGGGAAAGGGTGAGGACTTCACAATGTTGGCCT
  GTCAGAGCTTGATTAGAAGCCAAGACAGTGGCAGCAAAGGAAGACTTGGCCCAGGAAAAACCTGTGGGTT
  GTGCTAATTTCTGTCCAGAAAATAGGGTGGACAGAAGCTTGTGGGGTACATGGAGGAATTGGGACCTGGT
  TATGTTGTTATTCTCGGACTGTGAATTTTGGTGATGTAAAACAGAATATTCTGTAAACCTAATGTCTGTA
  TAAATAATGAGCGTTA
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_012104.3
• Summary: This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015]
• Locus ID: 23621