Crbn (NM_021449) Mouse Untagged Clone

CAT#: MC215825

Crbn (untagged) - Mouse cereblon (Crbn), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Crbn
• Synonyms: 2610203G15Rik; 2900045O07Rik; AF229032; AW108261; piL
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC215825 representing NM_021449
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCGGCGAGGGAGATCAGCAGGACGCTGCGCACAACATGGGAAACCACCTGCCGCTTCTGCCTGACA
  GTGAAGATGAAGATGATGAAATTGAAATGGAAGTTGAAGACCAAGATAGTAAAGAAGCCAGAAAACCGAA
  TATCATAAACTTTGACACCAGTCTGCCAACCTCACATACATACCTGGGAGCTGATATGGAGGAGTTCCAC
  GGGAGAACTTTGCATGACGACGACAGCTGCCAGGTGATCCCAGTCCTTCCTGAGGTGCTGATGATCCTGA
  TTCCTGGGCAGACACTCCCACTGCAGCTCTCTCACCCACAGGAAGTCAGCATGGTGCGGAACTTAATCCA
  GAAAGACAGGACCTTTGCAGTCCTTGCATACAGTAATGTGCAAGAAAGGGAAGCACAGTTTGGGACAACA
  GCAGAGATCTATGCCTATCGAGAAGAGCAGGAGTTTGGAATTGAAGTAGTGAAAGTGAAAGCAATTGGAA
  GGCAGCGGTTCAAGGTCCTCGAACTTCGAACACAGTCAGATGGAATCCAGCAAGCTAAAGTGCAGATTTT
  GCCAGAGTGTGTGTTGCCGTCAACCATGTCTGCAGTGCAGTTAGAATCACTCAATAAGTGCCAGGTATTT
  CCTTCAAAACCCATCTCCTGGGAAGACCAGTATTCATGTAAATGGTGGCAGAAATACCAGAAGAGAAAGT
  TTCACTGTGCAAATCTAACATCATGGCCTCGCTGGCTGTATTCATTATATGATGCTGAAACATTAATGGA
  TAGAATTAAGAAACAGCTACGTGAATGGGATGAAAATCTCAAAGATGATTCTCTTCCTGAAAATCCAATA
  GACTTTTCTTACAGAGTAGCTGCTTGTCTTCCTATTGATGATGTATTGAGAATTCAGCTCCTTAAAATCG
  GCAGTGCTATTCAACGGCTTCGCTGTGAATTGGACATCATGAACAAATGTACTTCCCTTTGCTGTAAACA
  ATGTCAAGAAACAGAAATAACGACAAAGAATGAAATATTTAGTTTATCCTTATGTGGTCCAATGGCAGCA
  TATGTGAATCCTCATGGATATGTACATGAGACACTGACTGTGTATAAAGCGTCCAACCTGAATCTGATAG
  GCCGGCCTTCTACAGTGCACAGCTGGTTTCCCGGGTATGCATGGACCATTGCCCAGTGCAAGATCTGTGC
  AAGCCATATTGGATGGAAATTTACAGCCACAAAAAAAGACATGTCACCTCAAAAATTTTGGGGCTTAACT
  CGCTCTGCTCTGTTACCCACAATTCCAGAGACTGAAGATGAAATAAGTCCAGACAAAGTAATACTTTGTT
  TATAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_021449
• ORF Size: 1335 bp
• Insert Size: 1335
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_021449.3, NP_067424.2
• RefSeq Size: 4064
• RefSeq ORF: 1335
• Locus ID: 58799
• Gene Summary: This gene encodes a protein with a Lon protease domain, a "regulators of G protein-signaling" (RGS)-like domain and a leucine zipper. It has been proposed to regulate the assembly and surface expression of large-conductance calcium-activated potassium channels in brain and to bind thalidomide. In humans mutation in this gene causes autosomal recessive nonsyndromic cognitive disability. In mouse deficiency of this gene serves as a model to study the molecular mechanisms governing learning and memory as they relate to intellectual disability. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 2013]
  Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1).