Galc (NM_008079) Mouse Untagged Clone

CAT#: MC220410

Galc (untagged) - Mouse galactosylceramidase (Galc), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Galc
• Synonyms: 2310068B06Rik; A930008M05Rik; AW212969; AW413532; Gacy; twi; twitcher
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC220410 representing NM_008079
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCTAACAGCCAACCTAAGGCTTCCCAGCAACGCCAAGCAAAAGTCATGACCGCCGCCGCGGGCTCGG
  CGAGCCGTGTTGCGGTGCCCTTATTGTTGTGTGCGCTGCTAGTGCCCGGTGGCGCCTACGTGCTAGACGA
  CTCCGACGGGCTGGGCCGGGAGTTCGATGGCATCGGCGCAGTCAGCGGCGGCGGGGCAACCTCCCGGCTT
  CTAGTAAATTACCCAGAGCCCTATCGTTCTGAAATACTGGATTATCTATTTAAGCCAAACTTTGGTGCCT
  CTTTGCATATTCTAAAAGTGGAGATAGGTGGTGATGGACAAACAACAGATGGCACTGAACCCTCGCACAT
  GCACTATGAGCTAGATGAGAATTATTTCCGAGGCTATGAGTGGTGGCTAATGAAGGAAGCTAAGAAGCGG
  AACCCAGATATTATACTTATGGGGTTGCCATGGTCATTCCCTGGATGGCTGGGCAAAGGCTTCAGCTGGC
  CTTATGTAAATCTTCAGCTCACTGCCTACTATGTTGTAAGATGGATTTTGGGTGCCAAGCATTATCATGA
  CCTGGACATTGATTATATTGGGATTTGGAATGAAAGGCCGTTTGACGCCAACTATATAAAGGAATTAAGA
  AAAATGCTGGATTATCAAGGTCTCCAGCGAGTGAGAATCATAGCGAGCGATAATCTCTGGGAGCCGATTT
  CCTCTTCCTTGCTGCTGGACCAGGAACTCTGGAAGGTGGTTGATGTTATAGGAGCTCACTATCCTGGAAC
  CTACACAGTGTGGAATGCAAAGATGTCAGGGAAGAAGCTGTGGTCATCTGAAGATTTTAGCACTATCAAC
  AGTAATGTTGGCGCAGGCTGTTGGAGTCGCATATTGAACCAGAATTACATCAATGGCAATATGACCTCCA
  CAATTGCTTGGAATTTGGTGGCTAGTTACTATGAAGAGTTGCCTTATGGACGAAGTGGGTTGATGACGGC
  CCAGGAGCCATGGAGTGGACATTATGTCGTAGCATCTCCTATCTGGGTATCAGCTCACACAACCCAGTTT
  ACTCAACCAGGCTGGTATTACCTGAAGACAGTGGGCCATCTAGAGAAAGGAGGAAGTTATGTTGCTCTGA
  CTGATGGCTTGGGAAACCTCACCATCATCATTGAAACTATGAGTCATCAACATTCTATGTGTATACGGCC
  ATATCTGCCATATTATAATGTCTCACATCAGCTGGCTACCTTCACTCTAAAGGGATCTTTGAGAGAAATA
  CAAGAGCTGCAGGTGTGGTATACCAAGCTGGGAACTCCGCAGCAGAGACTTCATTTTAAACAACTGGATA
  CTCTATGGCTCCTTGACGGCAGCGGCAGTTTCACACTGGAACTGGAGGAGGACGAGATATTTACGCTCAC
  CACTCTGACCACAGGTCGCAAAGGCAGCTACCCTCCCCCTCCCAGCTCGAAGCCCTTCCCAACCAACTAC
  AAGGATGATTTCAATGTTGAGTACCCACTTTTTAGTGAAGCTCCGAATTTTGCTGATCAGACTGGCGTGT
  TTGAGTACTACATGAATAATGAAGACCGTGAGCACCGCTTCACGCTGCGCCAAGTTCTCAACCAACGACC
  TATTACCTGGGCTGCAGACGCTTCCAGCACAATCAGTGTTATAGGCGATCACCACTGGACCAACATGACT
  GTGCAGTGCGATGTTTATATAGAGACCCCTCGGAGCGGCGGCGTATTCATTGCTGGAAGAGTGAATAAAG
  GTGGAATCTTGATTAGAAGTGCTACAGGAGTCTTTTTCTGGATTTTTGCAAATGGCTCTTACAGAGTCAC
  AGCTGACCTGGGTGGATGGATAACGTATGCTTCAGGACATGCGGACGTTACAGCTAAACGATGGTACACA
  CTCACCTTAGGCATTAAGGGTTATTTCGCCTTTGGTATGTTGAACGGCACGATCCTATGGAAAAACGTCC
  GTGTGAAATACCCAGGGCATGGCTGGGCTGCGATCGGAACACACACCTTCGAGTTTGCGCAGTTTGACAA
  CTTTCGCGTGGAAGCTGCTCGCTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_008079
• ORF Size: 2055 bp
• Insert Size: 2055
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_008079.4, NP_032105.2
• RefSeq Size: 3826
• RefSeq ORF: 2055
• Locus ID: 14420
• Gene Summary: This gene encodes galactosylceramidase, the lysosomal hydryolase involved in the catabolism of galactosylceramide. Mutations in this gene result in slow growth, tremors and hind leg weakness, collectively termed as the 'twitcher' phenotype. In humans, deficiency of this gene product causes a lysosomal storage disorder known as Krabbe disease. [provided by RefSeq, Dec 2014]