Timeless (NM_001136082) Mouse Untagged Clone

CAT#: MC223917

Timeless (untagged) - Mouse timeless homolog (Drosophila) (Timeless), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Timeless
• Synonyms: C77407; Debt69; tim
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC223917 representing NM_001136082
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACTTGTACATGATGAACTGTGAACTTCTAGCCACGTGTAGCGCCCTTGGGTACTTGGAAGGAGGGA
  CTTACCACAAGGAGCCGGATTGCCTGGAGAGTGTGAAGGATTTGATCCGATACCTGAGGCACGAGGATGA
  GACCCGAGATGTGCGGCAGCAGCTGGGAGCTGCACAGATCCTGCAGAGCGACCTCCTGCCAATCCTCACG
  CAGCATCGCCAGGACAAGCCTCTCTTCGATGCCGTGATCAGGCTGATGGTAAATTTGACACAGCCAGCCT
  TGCTCTGTTTTGGCAGCGTGCCTAAGGACTCCAGTGTACGGCACCATTTTCTGCAGGTTCTAACGTACCT
  GCAAGCCTACAAAGAGGCCTTTGCCAGTGAGAAGGCATTTGGAGTCCTCAGCGAGACCTTGTATGAATTG
  CTACAGCTGGGCTGGGAGGATCGGCAAGAAGAAGACAACTTGCTGATCGAGCGGATCCTTCTGCTGGTCA
  GAAATATTCTCCATGTCCCGGCCAACCTTGAGCAGGAGAAGAGTATCGATGATGATGCCAGCATCCACGA
  CCGTCTCCTTTGGGCAATTCACCTCAGTGGCATGGACGACTTGCTCCTCTTCCTGTCCAGCTCATCCGCC
  GAGCAGCAGTGGAGCCTCCATGTGCTGGAGATCATCTCCCTCATGTTCCGAGACCAGACCCCTGAGCAGC
  TAGCGGGAGTAGGGCAGGGACGCTTGGCTCAGGAGCGAAGCACGGATGTGGCAGAATTGGAGGTGCTGCG
  CCAACGGGAGATGGCGGAGAAGAGAGCTCGGGCCCTCCAGCGAGGAAACAGGCACTCTCGATTTGGGGGC
  TCCTACATTGTCCAGGGGTTGAAATCTATTGGGGAGAAGGATGTCGTCTTTCACAAAGGCCTTCACAATC
  TCCAGAACTACAGCTCAGATCTGGGAAAGCAGCCCAGGAGGGTGCCCAAGCGTCGTCAGGCTGCCCAGGA
  GCTGTCTGTCCATCGCCGCTCTGTCCTGAATGTGAGACTCTTCCTCAGAGACTTCTGCTCTGAGTTCCTG
  GAGAACTGCTACAACCCGCTCATGGGCGCGGTCAAGGATCATCTGCTTCGGGAGAGAGCGCAGCAGCATG
  ACGAGACTTACTACATGTGGGCAATGGCTTTCTTCATGGCCTTCAACCGAGCTGCCACCTTCCGCCCCGG
  CCTTGTTTCTGAGACCCTCAGTATCCGTACCTTTCACTTTGTGGAGCAGAACCTCACCAACTACTACGAG
  ATGATGCTGACAGACCGCAAGGAGGCCGCCTCCTGGGCGCGCAGGATGCACCTGGCCCTGAAGGCCTACC
  AGGAGCTGCTGGCCACGGTGAACGAGATGGACATGTGCCCAGATGAGGCTGTTAGGGAGAGCAGTCGTAT
  CATCAAAAACAACATTTTCTATATGATGGAGTACCGAGAACTATTCCTGGCGCTCTTTCGAAAGTTTGAT
  GAGAGATACCATCCACGCTCATTCCTTCGAGACCTGGTGGAAACCACCCACCTCTTCCTCAAAATGTTGG
  AGCGCTTTTGCCGGAGCCGCGGGAACCTGATGGTGCAGAACAAAAGAAAAAAGAGGAAAAAGAAAAAGAA
  GGTTCAGGACCAGGGTGTTGCTTTCTCACAAAGCCCCGGGGAGCTGGAGGCCATGTGGCCAGCCCTGGCA
  GAGCAGCTGCTGCAGTGTGCCCAGGACCCTGAGCTCAGTGTGGACCCCGTCGTTCCCTTTGATGCGGCCT
  CAGAGGTGCCAGTGGAGGAGCAGCGGGTAGAAGCCATGGTGAGGATCCAAGACTGCCTTACGGCTGGCCA
  GGCCCCGCAAGCCCTGGCCCTCCTGCGGTCTGCCCGGGAAGTGTGGCCTGAAGGAAATGCGTTTGGCTCT
  CCAGTCATTTCCCCAGGGGAAGAAATGCAGTTGCTGAAACAAATCCTCTCCACGCCCCTTCCCCGGCAGC
  AGGAGCCAGAAGAAGGAGATGCAGAGGAGGAAGAGGAAGAGGAGGAGGAAGAGGAGTTACAGGTGGTCCA
  GGTGTCAGAGAAGGAGTTTAACTTTCTGGAATACCTGAAACGCTTCGCATCCTCAACCATCGTGCGGGCC
  TACGTGCTTCTCCTGCGGAGCTACAGGCAGAACAGTGCTCACACCAACCACTGCATCGCCAAGATGCTGC
  ACCGGCTGGCCCATGGCCTGGGGATGGAAGCCCTGCTTTTCCAGCTGTCCCTGTTCTGCCTCTTCAATCG
  GCTGCTTAGTGACCCAGCTGCTGCGGCCTACAAAGAGCTAGTGACTTTTGCCAAATACATCATTGGCAAG
  TTCTTTGCGTTGGCTGCCGTGAACCAGAAAGCGTTTGTGGAGCTGCTGTTCTGGAAGAACACCGCAGTGG
  TTCGGGAAATGACCCAGGGATATGGCTCCCTCGACAGTGGGTCTTCCAGCCACAGAGCTCCTCTGTGGAG
  CCCTGAGGAAGAGGCCCAGCTTCAGGAACTATACCTCGCCCACAAGGATGTGGAAGGTCAAGATGTAGTG
  GAAACCATATTGGCGCACCTGAAAGTCGTTCCTCGAACACGCAAGCAGGTCATCCACCACCTGGTCCGGA
  TGGGCCTGGCCGACAGCGTCAAGGAGTTCCAGAAGAGGAAAGGGACCCAGATTGTCTTGTGGACGGAGGA
  CCAGGAGCTGGAGTTACAGCGGCTCTTTGAGGAGTTCCGGGACTCTGATGATGTTCTTGGTCAAATCATG
  AAGAATATCACAGCCAAACGTTCACGGGCTCGAGTAGTGGACAAACTGTTGGCCCTGGGGTTGGTGTCTG
  AGCGGAGGCAGCTATACAAGAAACGGAGAAAGAAGCTGGCGCCTTCTTGCATGAATGGAGAAAAGTCCCC
  GAGAGACCCCTGGCAGGAAGATCCGGAAGAGGAAGACGAACACTTGCCAGAGGACGAAAGTGAAGATGAG
  GAGAGTGAGGAAGGCTTGCCATCAGGACAGGGTCAGGGCAGCTCATCTCTCTCTGCTGAAAACCTCGGTG
  AGAGCCTTCGTCAGGAAGGCCTCTCTGCTCCCCTCCTGTGGCTCCAGAGCTCCCTGATCCGAGCAGCAAA
  TGACCGAGAAGAGGATGGCTGCTCCCAGGCAATCCCTCTGGTGCCTCTGACAGAGGAAAATGAGGAAGCA
  ATGGAGAACGAACAGTTTCAGCATCTGCTACGCAAGCTAGGGATCCGGCCGCCCAGCTCAGGGCAGGAAA
  CCTTCTGGAGAATTCCAGCCAAACTGAGCTCCACCCAGCTTCGGAGGGTGGCTGCTTCTTTGAGTCAGCA
  AGAAAACGAGGAGGAAAGGGAAGAGGAGCCAGAGCCAGGAGTCCCCGGAGAGCAGGGTCCCAGTGAGGAG
  CACCGGACAGAAGCCCTGAGAGCCCTTCTGTCAGCCCGTAAGAGGAAAGCAGGCCTGGGGCCTACAGAAG
  AGGAGGCCACTGGGGAGGAAGAATGGAACTCAGCGCCCAAGAAGCGGCAACTGCTGGACAGCGACGAAGA
  GGAAGATGATGAGGGGAGGAGGCAAGCAGTGTCGGGAACGCCAAGAGTCCACAGGAAGAAACGGTTTCAG
  ATTGAGGATGAGGATGACTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001136082
• ORF Size: 3591 bp
• Insert Size: 3591
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001136082.2, NP_001129554.1
• RefSeq Size: 4476
• RefSeq ORF: 3591
• Locus ID: 21853
• Gene Summary: The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
  Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 3' coding region, compared to variant 4. This variant is distinct from but the same length as variant 3. The resulting isoform (1) lacks one aa near the C-terminus, compared to isoform 2, and is distinct from isoform 3.