Cntnap1 (NM_016782) Mouse Untagged Clone

CAT#: MC224371

Cntnap1 (untagged) - Mouse contactin associated protein-like 1 (Cntnap1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cntnap1
• Synonyms: AI841080; Caspr; NCP1; Nrxn4; p190; shm
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224371 representing NM_016782
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGATGAGTCTCCGGCTCTTCAGCATCCTGCTCGCCACGGTGGTCTCTGGAGCTTGGGGCTGGGGCTACT
  ACGGTTGCAATGAGGAGCTGGTGGGGCCTCTGTATGCACGGTCTCTGGGCGCTTCTTCCTACTATGGACT
  CTTTACCACAGCCCGCTTTGCCCGGCTACATGGCATCAGTGGATGGTCGCCCCGGATTGGGGACCCGAAT
  CCCTGGCTGCAGATCGACTTAATGAAGAAGCATCGGATCCGGGCTGTGGCCACACAGGGAGCTTTTAATT
  CTTGGGATTGGGTCACACGTTACATGCTGCTCTACGGGGACCGTGTGGACAGCTGGACACCATTCTACCA
  AAAAGGGCACAATGCGACCTTCTTCGGGAATGTCAATGACTCGGCAGTGGTCCGCCATGACCTTCACTAC
  CACTTTACGGCTCGCTACATCCGCATCGTGCCACTGGCCTGGAACCCACGCGGCAAGATTGGCCTGAGGC
  TGGGCATCTATGGTTGTCCCTACACATCCAGCATCCTGTATTTTGACGGCGACGATGCCATCTCATACCG
  CTTCCAGCGAGGCGCCAGCCAAAGTCTTTGGGACGTGTTCGCTTTTAGTTTCAAGACAGAGGAGAAGGAT
  GGGCTGTTGCTGCACACCGAGGGCTCCCAGGGGGATTATGTGACGCTTGAACTGCAAGGGGCGCACCTGC
  TGCTGCACATGAGCCTGGGCAGCAGTCCCATCCAGCCAAGACCTGGTCACACCACGGTGAGCCTTGGTGG
  CGTTCTTAACGACCTAAGCTGGCACTATGTGCGGGTGGATCGATATGGCCGAGATGCAAATTTCACCCTG
  GATGGTTACGCCCATCACTTTGTGCTCAACGGCGACTTTGAAAGGCTGAATCTTGAAAATGAGATATTCA
  TCGGGGGTCTAGTGGGCGCAGCCCGTAAGAACCTGGCCTACCGCCATAACTTCCGTGGCTGCATAGAAAA
  CGTGATCTACAACCGGATCAACATTGCAGAAATGGCAGTGATGCGCCATTCGCGGATCACCTTTGAGGGT
  AATGTGGCTTTCCGTTGCTTGGATCCCGTTCCACACCCCATCAACTTCGGAGGCCCTCACAACTTCGTCC
  AAGTGCCTGGCTTTCCACGCCGAGGACGCTTAGCCGTCTCTTTTCGTTTCCGCACCTGGGACCTCACAGG
  GCTGCTCCTTTTCTCCCACTTGGGGGACGGGCTGGGTCATGTGGAGCTGATGCTTAGCGAAGGGCAAGTG
  AATGTATCCATCGCGCAGACTGGCCGCAAGAAGCTTCAGTTTGCTGCTGGGTACCGCCTGAATGATGGCT
  TCTGGCACGAGGTGAACTTTGTGGCACAGGAAAACCATGCAGTCATCAGTATTGATGATGTGGAAGGGGC
  AGAGGTCAGGGTTTCATACCCACTGCTGATCCGCACAGGGACTTCATACTTCTTTGGTGGTTGTCCCAAA
  CCAGCCAGTCGATGGGGCTGCCACTCCAACCAGACAGCATTCCATGGCTGCATGGAGCTGCTCAAGGTGG
  ACGGTCAACTGGTCAACCTCACTCTGGTAGAGTTTCGGAAGCTCGGTTATTTTGCTGAGGTCCTCTTTGA
  CACATGTGGCATCACAGACAGATGCAGCCCTAACATGTGTGAGCATGACGGACGATGCTACCAGTCTTGG
  GATGACTTCATCTGCTACTGCGAACTTACCGGCTACAAGGGAGTTACCTGCCACGAACCATTGTACAAGG
  AGTCCTGTGAGGCCTATCGGCTCAGTGGGAAATATTCTGGAAACTACACCATTGATCCTGATGGCAGTGG
  ACCCCTGAAGCCGTTTGTGGTGTATTGTGACATCCGAGAGAACCGAGCGTGGACAGTTGTGCGGCATGAC
  AGGCTGTGGACCACTCGAGTGACTGGTTCCAGCATGGACCGGCCCTTTCTGGGGGCCATCCAATACTGGA
  ATGCCTCCTGGGAGGAAGTCAGCGCTCTGGCCAATGCTTCCCAACACTGTGAGCAGTGGATCGAGTTTTC
  CTGCTACAATTCCCGGCTGCTCAACACTGCAGGAGGCTACCCCTACAGCTTTTGGATTGGCCGCAATGAG
  GAACAGCATTTCTACTGGGGAGGCTCCCAGCCTGGGATCCAGCGCTGTGCCTGTGGGCTGGACCAGAGCT
  GTGTGGACCCTGCACTGCACTGCAATTGTGATGCCGACCAGCCACAGTGGAGAACAGACAAGGGGCTCCT
  GACCTTTGTAGACCATCTGCCTGTCACTCAGGTAGTGGTAGGTGATACAAACCGCTCAAATTCTGAAGCT
  CAGTTCTTCCTGAGGCCTCTGCGCTGCTATGGTGACCGCAATTCCTGGAACACCATCTCCTTCCACACTG
  GAGCTGCACTGCGTTTCCCTCCGATCCGAGCCAACCACAGCCTCGATGTCTCATTCTACTTCAGGACCTC
  GGCTCCCTCGGGTGTCTTCCTAGAGAACATGGGGGGTCCTTTCTGCCGGTGGCGCCGACCTTACGTGAGA
  GTGGAGCTCAACACATCCCGGGATGTGGTCTTTGCCTTTGATATTGGCAATGGGGATGAGAACCTGACAG
  TGCACTCGGATGACTTTGAGTTTAACGATGATGAGTGGCATTTGGTCCGAGCTGAAATCAACGTGAAGCA
  GGCCCGGCTGCGAGTGGATCACCGGCCCTGGGTGCTAAGGCCCATGCCCCTGCAGACCTACATCTGGCTG
  GTGTATGACCAACCCCTCTATGTGGGATCTGCAGAGCTTAAGAGGCGCCCTTTTGTGGGCTGCTTGAGGG
  CCATGCGTTTGAATGGAGTGACTCTGAACTTGGAGGGCCGTGCCAATGCCTCTGAGGGCACCTTCCCCAA
  CTGCACCGGCCACTGCACCCACCCCCGGTTCCCCTGTTTCCACGGAGGACGCTGTGTGGAGCGATACAGC
  TACTACACATGTGACTGTGACCTCACAGCTTTTGATGGGCCATACTGCAATCACGATATTGGTGGATTCT
  TTGAGACCGGCACATGGATGCGCTATAACCTCCAGTCAGCACTGCGCTCTGCAGCCCGGGAGTTCTCACA
  CATGCTGAGCCGGCCAGTGCCGGGCTATGAGCCTGGCTATGTTCCAGGCTACGACACTCCTGGTTACGTG
  CCTGGATACCACGGCCCTGGGTACCGACTGCCCGAGTACCCGAGGCCCGGCCGGCCAGTGCCCGGGTATA
  GGGGGCCTGTCTACAATGTTACTGGAGAGGAGGTCTCCTTCAGCTTCAGCACCAACTCTGCTCCTGCCGT
  CCTGCTCTATGTCAGCTCCTTTGTACGTGACTACATGGCTGTGCTCATCAAGGAAGACGGGACCCTACAG
  CTTCGGTATCAGTTGGGCACCAGTCCCTATGTGTACCAGCTAACCACCCGGCCAGTGACTGATGGTCAGC
  CCCATAGTGTCAACATCACCCGGGTCTACCGAAACCTCTTTATCCAGGTGGACTACTTCCCGCTGACAGA
  ACAGAAGTTCTCTCTCCTGGTGGACAGCCAGCTGGACTCACCCAAGGCCTTGTATCTAGGGCGTGTGATG
  GAGACAGGAGTCATTGACCCAGAGATTCAGCGGTACAACACCCCAGGTTTCTCAGGCTGCCTGTCTGGTG
  TCCGGTTCAACAATGTGGCTCCTCTCAAGACCCATTTCCGAACCCCTCGGCCCATGACTGCTGAGCTGGC
  GGAGGCCATGCGGGTTCAAGGAGAACTGTCAGAATCTAACTGTGGAGCTATGCCACGCCTTGTCTCTGAG
  GTGCCACCAGAACTTGATCCCTGGTACCTGCCTCCAGATTTCCCATACTACCATGACGACGGATGGATTG
  CCATACTCTTAGGTTTTTTGGTGGCCTTCCTGCTGCTGGGGCTTGTGGGAATGCTGGTGCTGTTCTATCT
  GCAAAATCATCGATACAAGGGCTCCTACCACACCAACGAGCCCAAGGCCACCCACGATTCCCATCCTGGC
  GGCAAAGCTCCCCTCCCTCCCTCAGGCCCTGCCCAGGCCCCTGCCCCTACTCCAGCTCCCACACAGCTTC
  CAACCCCAGCCCCAGCCCCAGCCCCAGCCCCAGCCTCTGGCCCAGGCCCCAGAGACCAGAACCTCCCCCA
  GATCTTGGAGGAGTCCAGGTCTGAATGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_016782
• ORF Size: 4158 bp
• Insert Size: 4158
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_016782.2, NP_058062.2
• RefSeq Size: 5360
• RefSeq ORF: 4158
• Locus ID: 53321
• Gene Summary: Seems to play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the paranodal region of the axo-glial junction. In association with contactin may have a role in the signaling between axons and myelinating glial cells. Mice that lack CNTAP1 exhibit tremor, ataxia, and significant motor paresis. Normal paranodal junctions fail to form, and the organization of the paranodal loops is disrupted. Contactin is undetectable in the paranodes, and potassium channels are displaced from the juxtaparanodal into the paranodal domains. Also results in a severe decrease in peripheral nerve conduction velocity. [UniProtKB/Swiss-Prot Function]