Matk (NM_001285855) Mouse Untagged Clone

CAT#: MC227840

Matk (untagged) - Mouse megakaryocyte-associated tyrosine kinase (Matk), transcript variant 4

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Matk
• Synonyms: CHK; HYL; Ntk; p56ntk
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC227840 representing NM_001285855
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCAACGCGCTGGGCCCCTGGGACTCAATGCATGACCAAGTGTGAGAACTCTCGCCCCAAGCCCGGTG
  AGCTAGCCTTTCGAAAGGGTGACATGGTGACCATCTTGGAGGCCTGTGAGGACAAGAGCTGGTACCGAGC
  CAAGCACCATGGCAGTGGGCAGGAAGGGCTGCTGGCGGCCGCTGCTCTGCGACAGCGGGAGGCCCTCTCC
  ACAGACCCCAAGCTCAGCCTCATGCCATGGTTTCATGGCAAGATCTCCGGCCAGGAAGCCATACAGCAGC
  TGCAGCCACCCGAGGACGGGCTGTTCCTTGTGAGGGAATCAGCTCGTCACCCTGGAGACTATGTCTTGTG
  TGTCAGTTTCGGCCGTGACGTCATCCACTACCGTGTTTTGCATCGAGATGGGCACCTCACCATCGATGAG
  GCCGTGTGTTTCTGTAACCTGATGGACATGGTGGAGCACTACACCAAGGACAAGGGGGCCATCTGCACCA
  AGCTGGTGAAGCCAAGGAGGAAACAGGGCGCAAAGTCTGCAGAGGAGGAGCTCGCCAAGGCTGGCTGGCT
  ACTCGACCTGCAGCATCTGACTCTGGGAGCACAGATTGGAGAGGGGGAGTTTGGAGCCGTCCTACAGGGT
  GAGTACCTGGGACAGAAGGTGGCTGTGAAGAATATCAAGTGTGATGTGACAGCCCAGGCCTTCCTGGATG
  AGACGGCTGTGATGACGAAGCTGCAGCACAGGAACCTAGTGCGACTCCTGGGTGTGATCCTGCACCACGG
  CTTGTACATTGTCATGGAGCACGTGAGCAAGGGCAACCTGGTGAACTTCCTGCGCACGCGGGGCCGTGCT
  CTTGTGAGCACCTCTCAGCTTCTGCAGTTTGCTCTTCATGTTGCTGAAGGCATGGAATACCTGGAGAGCA
  AGAAGCTGGTGCACCGGGACCTGGCTGCTCGGAACATCCTGGTCTCTGAGGACTTGGTGGCCAAGGTCAG
  TGACTTTGGCTTAGCCAAGGCAGAGCGCAAGGGGCTGGACTCAAGCCGGCTGCCAGTCAAGTGGACGGCA
  CCTGAGGCTCTCAAAAACGGGCGGTTCTCCAGCAAGTCGGATGTCTGGAGTTTTGGGGTGCTGTTGTGGG
  AAGTCTTCTCTTATGGAAGAGCCCCATACCCCAAGATGTCGCTAAAGGAGGTTTCAGAGGCTGTGGAGAA
  GGGTTACCGCATGGAGCCCCCCGATGGCTGCCCAGGCTCTGTGCACACCCTCATGGGTAGCTGCTGGGAG
  GCAGAGCCTGCGCGCCGACCACCCTTCCGCAAAATAGTGGAGAAGCTGGGCCGTGAGCTCCGCAGTGTGG
  GTGTCTCGGCCCCCGCTGGGGGACAGGAGGCTGAGGGCTCAGCTCCCACACGGAGCCAGGACCCCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001285855
• ORF Size: 1398 bp
• Insert Size: 1398
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001285855.1, NP_001272784.1
• RefSeq Size: 1912
• RefSeq ORF: 1398
• Locus ID: 17179
• Gene Summary: Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (4) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform 1. Both variants 3 and 4 encode the same isoform (3). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.