Matk (NM_001285853) Mouse Untagged Clone

CAT#: MC227843

Matk (untagged) - Mouse megakaryocyte-associated tyrosine kinase (Matk), transcript variant 2

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Matk
• Synonyms: CHK; HYL; Ntk; p56ntk
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC227843 representing NM_001285853
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCAACGCAGCGCTGGGCCCCTGGGACTCAATGCATGACCAAGTGTGAGAACTCTCGCCCCAAGCCCG
  GTGAGCTAGCCTTTCGAAAGGGTGACATGGTGACCATCTTGGAGGCCTGTGAGGACAAGAGCTGGTACCG
  AGCCAAGCACCATGGCAGTGGGCAGGAAGGGCTGCTGGCGGCCGCTGCTCTGCGACAGCGGGAGGCCCTC
  TCCACAGACCCCAAGCTCAGCCTCATGCCATGGTTTCATGGCAAGATCTCCGGCCAGGAAGCCATACAGC
  AGCTGCAGCCACCCGAGGACGGGCTGTTCCTTGTGAGGGAATCAGCTCGTCACCCTGGAGACTATGTCTT
  GTGTGTCAGTTTCGGCCGTGACGTCATCCACTACCGTGTTTTGCATCGAGATGGGCACCTCACCATCGAT
  GAGGCCGTGTGTTTCTGTAACCTGATGGACATGGTGGAGCACTACACCAAGGACAAGGGGGCCATCTGCA
  CCAAGCTGGTGAAGCCAAGGAGGAAACAGGGCGCAAAGTCTGCAGAGGAGGAGCTCGCCAAGGCTGGCTG
  GCTACTCGACCTGCAGCATCTGACTCTGGGAGCACAGATTGGAGAGGGGGAGTTTGGAGCCGTCCTACAG
  GGTGAGTACCTGGGACAGAAGGTGGCTGTGAAGAATATCAAGTGTGATGTGACAGCCCAGGCCTTCCTGG
  ATGAGACGGCTGTGATGACGAAGCTGCAGCACAGGAACCTAGTGCGACTCCTGGGTGTGATCCTGCACCA
  CGGCTTGTACATTGTCATGGAGCACGTGAGCAAGGGCAACCTGGTGAACTTCCTGCGCACGCGGGGCCGT
  GCTCTTGTGAGCACCTCTCAGCTTCTGCAGTTTGCTCTTCATGTTGCTGAAGGCATGGAATACCTGGAGA
  GCAAGAAGCTGGTGCACCGGGACCTGGCTGCTCGGAACATCCTGGTCTCTGAGGACTTGGTGGCCAAGGT
  CAGTGACTTTGGCTTAGCCAAGGCAGAGCGCAAGGGGCTGGACTCAAGCCGGCTGCCAGTCAAGTGGACG
  GCACCTGAGGCTCTCAAAAACGGGCGGTTCTCCAGCAAGTCGGATGTCTGGAGTTTTGGGGTGCTGTTGT
  GGGAAGTCTTCTCTTATGGAAGAGCCCCATACCCCAAGATGTCGCTAAAGGAGGTTTCAGAGGCTGTGGA
  GAAGGGTTACCGCATGGAGCCCCCCGATGGCTGCCCAGGCTCTGTGCACACCCTCATGGGTAGCTGCTGG
  GAGGCAGAGCCTGCGCGCCGACCACCCTTCCGCAAAATAGTGGAGAAGCTGGGCCGTGAGCTCCGCAGTG
  TGGGTGTCTCGGCCCCCGCTGGGGGACAGGAGGCTGAGGGCTCAGCTCCCACACGGAGCCAGGACCCCTG
  A
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001285853
• ORF Size: 1401 bp
• Insert Size: 1401
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001285853.1, NP_001272782.1
• RefSeq Size: 1847
• RefSeq ORF: 1401
• Locus ID: 17179
• Gene Summary: Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) contains a distinct 5' UTR, lacks an in-frame portion of the 5' coding region and uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.