Adam23 (NM_001177600) Mouse Tagged ORF Clone

CAT#: MR223654

Adam23 (Myc-DDK-tagged) - Mouse a disintegrin and metallopeptidase domain 23 (Adam23), transcript variant 1

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Adam23
• Synonyms: AW046396; MDC3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR223654 representing NM_001177600
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAGCCGCCCGGCAGCATCTCCCGGCGGCCGACCCTGACGGGTTGCAGCCTTCCCGGCGCCTCCTGCG
  GCCCCGGCCGCTGCCCCGCCGGCCCGGTGCCGGCCCGCGCGCCGCCCTGCCGCCTGCTCCTCGTCCTTCT
  CCTGCTACCTGCGCTCGCCACCTCATCCCGGCCCCGTGCCCGGGGGGCCGCTGCGCCCAGCGCTCCGCAC
  TGGAATGAAACTGCAGAAAAAACCCTGGGAGTCCTGGCAGATGAAGACAACACATTGCAACAAAATAGCA
  GCAGCAGAAATACCAGCTACAGCAGTGCAGTGCAAAAAGAAATCACACTGCCTTCAAGACTGGTGTATTA
  CATCAACCAGGACTCAGAAAGCCCCTATCATGTTCTTGACACAAAGGCCAGACACCAACAGAAACACAAT
  AAGGCTGTGCATCTGGCCCAGGCAAGCTTCCAGATCGAAGCTTTCGGCTCCAAGTTCATTCTTGACCTCA
  CACTGAACAATGGTTTGCTATCTTCTGACTACGTGGAGATCCACTATGAAGACGGGAAGCAGATGTACTC
  TAAGGGTGGAGAGCACTGTTACTACCACGGAAGCATCAGAGGCGTCAAGGATTCCAGGGTGGCTCTATCG
  ACCTGCAATGGACTCCATGGCATGTTTGAGGATGACACCTTTGTGTATATGATAGAGCCGCTGGAACTGA
  CTGATGATGAGAAAAGCACAGGCCGACCACACATAATCCAGAAAACCTTGGCAGGACAGTATTCTAAGCA
  GATGAAGAATCTCAGCACAGATGGCAGTGACCAGTGGCCTTTGCTACCTGAATTACAATGGCTGAGAAGA
  AGGAAAAGAGCGGTCAATCCATCTCGTGGTGTGTTTGAAGAAATGAAGTATTTGGAGCTTATGATTGTTA
  ATGATCACAAGACGTATAAGAAGCACCGCTCTTCTCACGCGCATACCAACAACTTCGCAAAGTCTGTGGT
  CAACCTTGTAGATTCTATTTACAAGGAACAGCTCAACACCAGGGTTGTCCTGGTGGCTGTCGAGACCTGG
  ACCGAGAAGGATCACATTGACATCACCATCAACCCCGTGCAGATGCTACATGACTTCTCCAAGTACCGGC
  AGCGAATCAAACAGCACGCTGACGCGGTCCACCTCATCTCGCGCGTGACATTCCATTATAAGAGAAGCAG
  TCTGAGTTACTTTGGAGGCGTGTGTTCTCGAATAAGAGGGGTTGGTGTGAATGAGTATGGTCTTCCAATG
  GCGGTGGCACAAGTATTATCACAGAGCCTGGCTCAAAACCTTGGAATCCAGTGGGAACCTTCGAGCAGGA
  AGCCAAAATGTGAATGCATAGAGTCCTGGGGCGGCTGCATCATGGAAGAAACAGGGGTGTCCCACTCTCG
  AAAGTTCTCAAAGTGCAGCATTTTGGAGTACAGAGACTTTTTACAGAGAGGTGGCGGAGCATGTCTTTTC
  AATAGGCCAACTAAGCTGTTTGAGCCCACGGAATGTGGAAATGGATATGTGGAGGCCGGGGAGGAATGCG
  ACTGTGGTTTCCATGTGGAATGCTATGGAGTTTGCTGTAAGAAGTGTTCGCTCTCCAATGGGGCCCACTG
  CAGTGACGGCCCCTGCTGTAACAACACCTCATGTCTTTTTCAGTCACGAGGGTATGAATGTCGGGATGCC
  GTAAACAGCTGTGATATCACCGAGTACTGCACTGGAGACTCTGGCCAGTGCCCACCGAACCTCCATAAAC
  AAGATGGCTATAGCTGCAATCAAAATCAGGGTCGCTGCTACAATGGCGAGTGCAAGACAAGGGACAATCA
  ATGCCAGTACATCTGGGGGACAAAGGCTGCGGGGTCAGACAAGTTCTGCTATGAAAAGCTGAACACGGAA
  GGCACCGAGAAGGGCAATTGTGGAAAGGATGGAGACCGGTGGATCCCGTGCAGCAAGCATGATGTGTTCT
  GTGGATTTCTGCTTTGCACCAATCTTACCCGAGCTCCACGTATCGGTCAACTTCAAGGAGAGATCATCCC
  GACTTCCTTCTATCATCAAGGCCGAGTGATTGACTGCAGTGGTGCTCATGTAGTTTTAGACGATGATACA
  GACGTGGGTTACGTTGAAGATGGGACTCCGTGTGGCCCCTCCATGATGTGCTTAGATCGGAAGTGCCTAC
  AGATTCAAGCCCTGAATATGAGCAGCTGCCCACTTGACTCAAGGGGTAAAGTCTGCTCCGGCCACGGGGT
  GTGTAGCAACGAAGCCACCTGCATCTGTGATTTCACTTGGGCAGGCACAGACTGCAGCATCCGGGATCCA
  GTTCGGAACCCCAACCCCCCTAAGGATGAAGGCCCTAAGGGTTTGTATGATTCCGGTTTTAGATCACTGC
  AGATTATTCATCTCCCCTCTCCCACTGCAGCAGTAATCCACTTCCACAGCTTCAGAAGGAGGCACACAGG
  AATATATCCTTTTGCCACAGAGATGCGCCATCCTGTGTGTACCACACTTTCAGAAGCATAT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR223654 representing NM_001177600
  Red=Cloning site Green=Tags(s)
  
  MKPPGSISRRPTLTGCSLPGASCGPGRCPAGPVPARAPPCRLLLVLLLLPALATSSRPRARGAAAPSAPH
  WNETAEKTLGVLADEDNTLQQNSSSRNTSYSSAVQKEITLPSRLVYYINQDSESPYHVLDTKARHQQKHN
  KAVHLAQASFQIEAFGSKFILDLTLNNGLLSSDYVEIHYEDGKQMYSKGGEHCYYHGSIRGVKDSRVALS
  TCNGLHGMFEDDTFVYMIEPLELTDDEKSTGRPHIIQKTLAGQYSKQMKNLSTDGSDQWPLLPELQWLRR
  RKRAVNPSRGVFEEMKYLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKEQLNTRVVLVAVETW
  TEKDHIDITINPVQMLHDFSKYRQRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRIRGVGVNEYGLPM
  AVAQVLSQSLAQNLGIQWEPSSRKPKCECIESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGGGACLF
  NRPTKLFEPTECGNGYVEAGEECDCGFHVECYGVCCKKCSLSNGAHCSDGPCCNNTSCLFQSRGYECRDA
  VNSCDITEYCTGDSGQCPPNLHKQDGYSCNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTE
  GTEKGNCGKDGDRWIPCSKHDVFCGFLLCTNLTRAPRIGQLQGEIIPTSFYHQGRVIDCSGAHVVLDDDT
  DVGYVEDGTPCGPSMMCLDRKCLQIQALNMSSCPLDSRGKVCSGHGVCSNEATCICDFTWAGTDCSIRDP
  VRNPNPPKDEGPKGLYDSGFRSLQIIHLPSPTAAVIHFHSFRRRHTGIYPFATEMRHPVCTTLSEAY
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001177600
• ORF Size: 2511 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001177600.1, NP_001171071.1
• RefSeq Size: 2880
• RefSeq ORF: 2514
• Locus ID: 23792
• MW: 93.5 kDa
• Gene Summary: This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an inactive metalloprotease and disintegrin domains. Transgenic disruption of this gene in mice results in postnatal neurological defects including tremor and ataxia resulting in death by 2 weeks of age. [provided by RefSeq, Sep 2015]