PMVK (NM_006556) Human Tagged ORF Clone
CAT#: RC202867L3
- LentiORF®
Lenti ORF clone of Human phosphomevalonate kinase (PMVK), Myc-DDK-tagged
"NM_006556" in other vectors (4)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | PMVK |
Synonyms | HUMPMKI; PMK; PMKA; PMKASE; POROK1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC202867).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_006556 |
ORF Size | 576 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_006556.3, NP_006547.1 |
RefSeq Size | 1307 |
RefSeq ORF | 579 |
Locus ID | 10654 |
Domains | P-mevalo_kinase |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Terpenoid backbone biosynthesis |
MW | 22 kDa |
Gene Summary | This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC319138 | PMVK (untagged)-Human phosphomevalonate kinase (PMVK) |
USD 310.00 |
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RC202867 | PMVK (Myc-DDK-tagged)-Human phosphomevalonate kinase (PMVK) |
USD 98.00 |
|
RG202867 | PMVK (GFP-tagged) - Human phosphomevalonate kinase (PMVK) |
USD 460.00 |
|
RC202867L4 | Lenti ORF clone of Human phosphomevalonate kinase (PMVK), mGFP tagged |
USD 620.00 |
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