Mrvi1 (NM_001105210) Rat Untagged Clone

CAT#: RN200094

Mrvi1 (untagged ORF) - Rat MRV integration site 1 homolog (mouse) (Mrvi1), transcript variant 2, (10 ug)

Specifications

Product Data

• Type: Rat Untagged Clone
• Tag: Tag Free
• Symbol: Mrvi1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >RN200094 representing NM_001105210
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCCCACATTCCTGAGGATGAGGAGCCCCCCGGAGAGCCACAGGCAGCCCAGACCCAAGACTCTCCCT
  CTGCAGGACCGTTTTGCAGCCCTCCCACAATCATCCTGACGGGGGATGCCAGTTCACCTGGAGGAGAGAC
  TGACACAAATCTGGTCAAGAGGGCTCCCAGCCCCCACCGCAGGCTTTCCCACCGACACCTGAAGGTCTCC
  ACTGCCTCGCTGACTTCTGTGGACCCCTTGGGGCACGTCATTGACCTGGTAAATGACCAGCTGCCGGACA
  TCAGCATCTCAGAAGAGGACAAGAAGAAAAACCTGGCACTTCTAGAAGAAGCCAAGTTGGTTAGCGAGCG
  GTTCCTGACCCGCCGCGGGAGGAGATCAAGGAGCAGCCTCGGAGACGCCCCATCAGCTGTTTCTCCAAAC
  CTCAGCTCTGGAGCTTCTCCTGCATCCTCTAGGAGTTGCTCGTTCACCATCTCCACACCACCAGGTTTTG
  ACACATGCAGTGGCCCACAGTCCCCTCTGCCGGGATCACCAGCACAGCAAAAGGGACATGAGGATGATGT
  CTTCTCGTCTCACCTCGGAGAGCCTAATGCCTCCAAAGGGCTAGCTGACCGGAAGCAGAATGACCAGAGG
  AAAGTGTCTCAAGGCAGACTGGCTCCTCGCTCTCCCACAGTGGAGAAATCCAAAGAACTTTCAGTAGAAC
  AAAAGGAAAACTTCGATCCCCTTCAGCATCTGGAGGCCACACCCATGGCTCAGACCTCTGGAGCAAGCGT
  CAGTGGGAAAATGGCGCTGAACAGTCCCCAGCCTGGCCCTGCGGAGATGGAGCTGGGGAGGCAGCTTCTG
  AAGACAGCCAGGGAAGACAACCCTCTGCCCAGAACCACAGTCCAGGGCTCAGGAGGAACGGCCTCCCCAC
  ATTCTCAGGGACAGGGCTCTGCTGGAGAGCTTATGGGGCCCAAGGCTGGCTCCAAGGCTGAGCCGAGGCC
  TCCTGTGTCCCGGCCCCCTCTGATTCGGGGGGTCTCCTGGGACAGCAGCCCTGAAGAACCTGGTCCCCTG
  CTGCAAAAGGTGCTCGCTAAGCTGCCTCTGGCAGAGGAAGAAAAGCGGTTTCCAGGCAAAGCCAAGCCAG
  CCAAGCCACCGGGGCTCAAAGACTTCCAGATACAAGTACAGCCGGTGCGCATGCAGAAGCTGACCAAGCT
  TCGGGAGGAACACATCCTGATGAGAAACCAGAACCTGGTGGGGTTCAAGCTCCCTGAACTGAGTGAAGCT
  GCAGAGCAAGACAAAGGAGTCTCATCTGAGCTTGCCCCAGCAGCTGAGGAAGAAGAATCAAAGAGTGGTC
  TGGATGTGATGCCCAACATTTCTGACATATTGCTACGTAAACTTAGGGTTCACAAGTCACTCACTGGAAG
  CGCCCCTCCGCTCACAGAAAAGGAAGTCGAGAACGTGTTTGTACAACTGTCCTTGGCCTTTAGAAATGAC
  AGCTACACCTTGGAGTCTAGGATTAACCAGGCTGAAAGGGAACGCAACTTGACGGAAGAGAACACCGAGA
  AGGAACTGGAAAACTTCAAAGCCTCTATTACGTCCTCAGCATCCATCTGGTACCACTGCGAGCACCGGGA
  GACCTACCAGAAGCTTCTGGAAGACATCGCAGTCTTGCATCGTCTGGCTGCACGCCTCTCCAGCCGGGCT
  GAAGTGGTGGGTGCTGTGCGCCAGGAAAAGCGCATGTCAAAGGCCACGGAAGTGATGATGCAGTATGTGG
  AGAATCTGAAGAGAACGTACGAGAAGGACCATGCTGAGCTCATGGAATTTAAGAAACTCGCAAATCAGAA
  TTCTAGTCGCAGCTGTGGGCCCTCTGAAGACGGGGTTCCTCGCACGGCGCGATCTATGTCCCTCACGATG
  GGAAAGAACATGCCCCGTCGGAGGGTCAGCGTTGCTGTGGTTCCCAAGTTTAATGCCCTGAACCTGCCTG
  GCCAAGCCCCCAGCTCATCACCCATGCCCTCTCTCCCAGCTCTGTCTGAATCGACCAACGGGAGAAGCAG
  CATCTCCACCTCTCCAGTGCTGCCTGCACTTTTGGAAAATGGAAAGACAAATGCAGAGGCTAACTGTGAA
  GTGTGCGCCCCTGTGCCACTCCCAAGCTACCCGGAGGAGACGAGCCAAGAGGCCAAGGCCAGAGCAGAGG
  AAGAAGCCTACAACAAAGGATACCAGGAAGGGGTAAAGAAGACCGAAGAACTTCAAGACCTGAAGGAGGA
  GGAAGAGGAACAGAAGGCAGAGAGTCCTCAGGAACCAGAAGAGGTCGAAGAAACCCAGGAAGACGAGAAG
  GACCAGAGAAGCAGCAAACTTGAAGAACTGGTCCACTTCCTACAAGTCATGTATCCCAAATTGTGTCAAC
  ACTGGCAAGTGATCTGGATGATGGCCGCTGTGATGCTGGTCTTGAGTGTTGTGCTTGGGCTCTACAGTTC
  CTATAACTCCTGCACGGAGCAGGCCGACGGGCCCCCTGGGAGATCCACCTGCTCTGCAGCCCAGCGGGAC
  TCCTGGTGGAGCTCGGGACTCCAGCAAGAGCTGCCAGCAGAGCAGTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001105210
• ORF Size: 2568 bp
• Insert Size: 2568
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001105210.1, NP_001098680.1
• RefSeq Size: 6182
• RefSeq ORF: 2568
• Locus ID: 308899
• Gene Summary: This gene is similar to a putative mouse tumor suppressor gene that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. Studies in mouse suggest that MRV integration at the homologous mouse gene induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013]
  Transcript Variant: This variant (2) contains an additional 5' exon, is differently spliced at the initial coding exon, and initiates translation from an in-frame, downstream AUG compared to variant 1. The resulting isoform (b) has a shorter N-terminus compared to isoform a. Sequence Note: This RefSeq transcript and protein were derived from genomic sequence because no rat transcript was available. The extent of this transcript and the encoded protein are supported by orthologous mouse data.