Mapk10 (NM_012806) Rat Untagged Clone

CAT#: RN203224

Mapk10 (untagged ORF) - Rat mitogen activated protein kinase 10 (Mapk10), (10 ug)

Specifications

Product Data

• Type: Rat Untagged Clone
• Tag: Tag Free
• Symbol: Mapk10
• Synonyms: Jnk3; SAPb; SAPKC; Serk2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >RN203224 representing NM_012806
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGCAAAAGCAAGGTAGATAACCAGTTCTACAGTGTGGAAGTGGGAGACTCAACCTTCACAGTTCTAA
  AGCGCTACCAGAACCTGAAGCCGATCGGCTCTGGGGCTCAGGGAATAGTTTGTGCTGCGTATGACGCTGT
  CCTCGACAGAAATGTGGCCATTAAGAAGCTCAGCAGACCCTTCCAGAACCAAACTCATGCCAAGAGGGCT
  TACCGGGAGCTGGTCCTCATGAAGTGTGTGAACCATAAAAACATTATTAGCTTATTAAATGTCTTTACAC
  CCCAGAAAACACTGGAGGAGTTCCAAGATGTTTACTTAGTGATGGAACTGATGGACGCCAACTTGTGTCA
  GGTGATTCAGATGGAGCTGGACCACGAGCGGATGTCGTACTTGCTGTACCAGATGCTGTGCGGCATCAAA
  CACCTCCACTCCGCTGGGATCATCCACAGGGACTTAAAACCCAGTAACATCGTAGTCAAGTCTGATTGCA
  CACTGAAAATCCTGGACTTTGGACTGGCCAGGACAGCGGGCACAAGCTTCATGATGACTCCGTATGTGGT
  GACGAGATATTACAGAGCCCCCGAGGTCATCCTGGGCATGGGCTACAAGGAGAACGTGGACATATGGTCT
  GTGGGCTGCATCATGGGAGAAATGGTTCGTCACAAAATCCTCTTTCCCGGAAGGGACTATATTGACCAGT
  GGAACAAAGTCATAGAGCAGCTAGGAACTCCGTGTCCAGAATTCATGAAGAAATTGCAGCCCACCGTCAG
  AAACTACGTGGAGAACCGGCCCAAGTATGCAGGCCTCACCTTCCCCAAGCTCTTTCCAGATTCCCTCTTC
  CCAGCGGATTCCGAGCACAATAAACTTAAAGCCAGCCAAGCCAGGGACTTGTTGTCAAAGATGTTAGTGA
  TTGACCCAGCGAAGAGGATATCGGTGGATGACGCATTGCAGCATCCGTACATCAACGTTTGGTACGACCC
  TGCTGAAGTGGAGGCGCCTCCGCCTCAGATATATGACAAGCAACTGGATGAAAGGGAGCACACCATCGAA
  GAATGGAAAGAACTCATCTACAAGGAAGTAATGAACTCAGAAGAGAAGACTAAGAACGGCGTAGTCAAAG
  GCCAGCCCTCACCTTCAGGTGCAGCAGTGAACAGCAGTGAGAGTCTCCCTCCATCCTCGTCTGTCAACGA
  CATCTCCTCCATGTCCACCGACCAGACCCTCGCATCCGACACTGACAGCAGCCTGGAAGCCTCGGCGGGA
  CCGCTGGGTTGTTGCAGGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_012806
• ORF Size: 1281 bp
• Insert Size: 1281
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012806.2, NP_036938.2
• RefSeq Size: 2786
• RefSeq ORF: 1281
• Locus ID: 25272
• Gene Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
  Transcript Variant: This variant (2) uses an alternate acceptor splice site in the 5' region, which results in translation initiation from an in-frame, downstream start codon compared to variant 1. The encoded isoform (2, also known as SAPK beta) has a shorter N-terminus compared to isoform 1.