Acmsd (NM_134372) Rat Untagged Clone

CAT#: RN212337

Acmsd (untagged ORF) - Rat aminocarboxymuconate semialdehyde decarboxylase (Acmsd), (10 ug)

Specifications

Product Data

• Type: Rat Untagged Clone
• Tag: Tag Free
• Symbol: Acmsd
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >RN212337 representing NM_134372
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAAATTGACATCCACACTCACATTCTACCAAAGGAATGGCCTGATCTAGAAAAGAGGTTTGGCTATG
  GAGGCTGGGTGCAGCTCCAACAGCAAGGCAAGGGAGAAGCAAAGATGATGAAAGACGGGAAGGTCTTCAG
  AGTGATCCAACAGAACTGCTGGGACCCAGAAGTCCGCATCAGAGAAATGAACCAGAAAGGAGTGACAGTG
  CAAGCTCTTTCCACAGTTCCCGTCATGTTTAGTTACTGGGCCAAACCTAAGGACACTTTGGAACTGTGCC
  AGTTTTTAAACAATGACCTCGCTGCCACGGTGGCCAGATACCCTCGAAGGTTTGTGGGTTTGGGGACATT
  GCCTATGCAAGCCCCGGGGCTGGCTGTCGAGGAGATGGAGCGTTGTGTAAAGGAGCTAGGATTTCCAGGA
  ATCCAGATTGGATCCCACATCAACATGTGGGACCTGAATGACCCGGAACTCTTCCCCATCTACACGGCGG
  CTGAGAGGCTGAATTGTTCTCTGTTCGTGCATCCCTGGGATATGCAGATGGATGGACGGATGGCCAAATA
  CTGGCTGCCTTGGCTCGTAGGAATGCCATCGGAGACCACCACGGCCATTTGCTCCATGATCATGGGTGGG
  GTGTTCGAGAAGTTTCCCAAACTCAAAGTGTGTTTTGCACATGGAGGTGGTGCTTTCCCCTTCACCATAG
  GAAGAATTGCTCATGGATTTAACATGCGCCCAGATCTCTGTGCCCGGGACAATTCATCTGACCCCAGAAA
  ATACCTTGGCTCCTTCTACACGGACTCCCTGGTTCATGATCCTCTGTCTCTCAAGCTATTGACAGATGTT
  ATAGGGAAGGATAGAGTTATTCTGGGAACTGATTACCCCTTTCCACTAGGTGAGCAGGAGCCTGGGAAGT
  TGATAGAGTCTATGGCAGACTTTGATGAAGAAACAAAGGATAAACTTACAGCTGGCAATGCCTTGACTTT
  TTTGGGTCTTGAGAGAAAACTATTTGAATGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_134372
• ORF Size: 1011 bp
• Insert Size: 1011
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_134372.1, NP_599199.1
• RefSeq Size: 1011
• RefSeq ORF: 1011
• Locus ID: 171385
• Gene Summary: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway. [UniProtKB/Swiss-Prot Function]