Bnip3 (NM_053420) Rat Tagged ORF Clone

CAT#: RR213871

Bnip3 (Myc-DDK-tagged ORF) - Rat BCL2/adenovirus E1B 19 kDa-interacting protein 3 (Bnip3), nuclear gene encoding mitochondrial protein, (10 ug)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Bnip3
• Synonyms: MGC93043
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR213871 representing NM_053420
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCGCAGAGCGGGGAGGAGAACCTGCAGGGCTCCTGGGTAGAACTGCACTTCAGCAATGGGAATGGGA
  GCAGCGTTCCAGCTTCCGTCTCTATTTATAATGGTGACATGGAAAAAATACTGCTGGATGCGCAGCATGA
  ATCTGGACGAAGCAGCTCCAAGAGCTCTCACTGTGACAGCCCACCTCGCTCCCAGACACCACAAGATACC
  AACAGAGCTGAAATAGACACCCACAGCTTTGGTGAGAAAAACAGCACTCTGTCTGAGGAAGATTATATTG
  AGAGAAGAAGAGAAGTTGAAAGTATCCTGAAGAAAAACTCAGATTGGATATGGGATTGGTCAAGTCGGCC
  AGAAAATGTTCCCCCCAAGGAGTTCCTTTTTAAACACCCGAAGCGCACAGCTACTCTCAGCATGAGAAAC
  ACAAGCGTTATGAAGAAAGGGGGTATTTTCTCAGCAGACTTTCTGAAGGTTTTCCTTCCATCTCTGTTAC
  TGTCTCATCTGTTAGCCATTGGATTGGGGATCTACATTGGAAGGCGTCTGACAACTTCCACTAGTACCTT
  T
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR213871 representing NM_053420
  Red=Cloning site Green=Tags(s)
  
  MSQSGEENLQGSWVELHFSNGNGSSVPASVSIYNGDMEKILLDAQHESGRSSSKSSHCDSPPRSQTPQDT
  NRAEIDTHSFGEKNSTLSEEDYIERRREVESILKKNSDWIWDWSSRPENVPPKEFLFKHPKRTATLSMRN
  TSVMKKGGIFSADFLKVFLPSLLLSHLLAIGLGIYIGRRLTTSTSTF
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_053420
• ORF Size: 561 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_053420.1, NM_053420.2, NM_053420.3, NP_445872.1
• RefSeq Size: 1641
• RefSeq ORF: 564
• Locus ID: 84480
• MW: 21 kDa
• Gene Summary: heterodimerizes and antagonizes the activity of prosurvival proteins (Bcl-2, Bcl-XL) and promotes apoptosis; provokes mitochondrial defects and cell death of ventricular myocytes during hypoxia [RGD, Feb 2006]