FUK (NM_145059) Human Untagged Clone

CAT#: SC100065

FUK (untagged)-Human fucokinase (FUK)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FUK
• Synonyms: 1110046B12Rik; CDGF2; FUK
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_145059, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGCAGCCGAAGGGAGTTGATTGGACAGTCATCATCCTGACCTGCCAGTACAAGGACAGTGTCCAGG
  TCTTTCAGAGAGAACTGGAAGTGCGGCAGAAGCGGGAGCAGATCCCTGCTGGGACGCTGTTACTGGCCGT
  GGAGGACCCAGAGAAGCGTGTGGGCAGCGGAGGAGCCACCCTCAACGCCCTGCTGGTGGCTGCTGAACAC
  CTGAGTGCCCGGGCAGGCTTCACTGTGGTCACATCCGATGTCCTGCACTCGGCCTGGATCCTCATTCTGC
  ACATGGGTCGAGACTTCCCCTTTGATGACTGTGGCAGGGCTTTCACCTGCCTCCCCGTGGAGAACCCCGA
  GGCCCCCGTGGAAGCCTTGGTCTGCAACCTGGACTGCCTGCTGGACATCATGACCTATCGGCTGGGCCCG
  GGCTCCCCGCCAGGCGTGTGGGTCTGCAGCACCGACATGCTGCTGTCTGTTCCTGCAAATCCTGGTATCA
  GCTGGGACAGCTTCCGGGGAGCCAGAGTGATCGCCCTCCCAGGGAGCCCGGCCTACGCTCAGAATCATGG
  CGTCTACCTAACTGACCCCCAGGGCCTTGTTTTGGACATTTACTACCAGGGCACTGAGGCAGAGATTCAG
  CGGTGTGTCAGGCCTGATGGGCGGGTGCCACTGGTCTCTGGGGTTGTCTTCTTCTCTGTGGAGACTGCCG
  AGCGCCTCCTAGCCACCCACGTGAGCCCGCCCCTGGATGCCTGCACCTACCTAGGCTTGGACTCCGGAGC
  CCGGCCTGTCCAGCTGTCTCTGTTTTTTGACATTCTCCACTGCATGGCTGAGAACGTGACCAGGGAGGAC
  TTCCTGGTGGGGAGGCCCCCAGAGTTGGGGCAAGGCGATGCAGATGTAGCGGGTTATCTGCAGAGCGCCC
  GGGCCCAGCTGTGGAGGGAGCTTCGCGATCAGCCCCTTACCATGGCCTATGTCTCCAGCGGCAGCTACAG
  CTACATGACCTCCTCAGCCAGTGAGTTCCTGCTCAGCCTCACACTCCCCGGGGCTCCTGGGGCCCAGATT
  GTGCACTCCCAGGTGGAGGAGCAGCAGCTTCTGGCGGCCGGGAGCTCTGTGGTCAGCTGCCTGCTGGAGG
  GCCCTGTCCAGCTGGGTCCTGGGAGCGTCCTGCAGCACTGCCACCTGCAGGGCCCCATTCACATAGGCGC
  TGGCTGCTTGGTGACTGGCCTGGATACAGCCCACTCCAAGGCCCTGCATGGCCGGGAGCTGCGTGACCTT
  GTCCTGCAGGGACACCACACGCGGCTACACGGCTCCCCGGGCCACGCCTTCACCCTCGTTGGCCGTCTGG
  ACAGCTGGGAGAGACAGGGGGCAGGCACATATCTCAACGTGCCCTGGAGTGAATTCTTCAAGAGGACAGG
  TGTTCGAGCCTGGGACCTGTGGGACCCTGAGACGCTGCCCGCAGAGTACTGCCTTCCCAGCGCCCGCCTC
  TTTCCTGTGCTCCACCCCTCGAGGGAGCTGGGACCCCAGGACCTGCTGTGGATGCTGGACCACCAGGAGG
  ATGGGGGCGAGGCCCTGCGAGCCTGGCGGGCCTCCTGGCGCCTGTCCTGGGAGCAGCTGCAGCCGTGCCT
  GGATCGGGCTGCCACGCTGGCCTCTCGCCGGGACCTGTTCTTCCGCCAGGCCCTGCATAAGGCGCGGCAC
  GTGCTGGAGGCCCGGCAGGACCTCAGCCTGCGCCCGCTGATCTGGGCTGCTGTCCGCGAGGGCTGCCCCG
  GGCCCCTGCTGGCCACGCTGGACCAGGTTGCAGCTGGGGCAGGAGACCCTGGTGTGGCGGCACGGGCACT
  GGCCTGTGTGGCGGACGTCCTGGGCTGCATGGCAGAGGGCCGTGGGGGCTTGCGGAGCGGGCCAGCTGCC
  AACCCTGAGTGGATGCGGCCCTTCTCATACCTGGAGTGTGGAGACCTGGCAGCGGGCGTGGAGGCGCTTG
  CCCAGGAGAGGGACAAGTGGCTAAGCAGGCCAGCCTTGCTGGTGCGAGCGGCCCGCCACTATGAGGGGGC
  TGGTCAGATCCTGATCCGCCAGGCTGTGATGTCAGCCCAGCACTTTGTCTCCACAGAGCAGGTGGAACTG
  CCGGGACCTGGGCAGTGGGTGGTGGCTGAGTGCCCGGCCCGTGTGGATTTCTCTGGGGGCTGGAGTGACA
  CGCCACCCCTTGCCTATGAGCTTGGCGGGGCTGTGCTGGGCCTGGCTGTGCGAGTGGACGGCCGCCGGCC
  CATCGGAGCCAGGGCACGCCGCATCCCGGAGCCTGAGCTGTGGCTGGCGGTGGGGCCTCGGCAGGATGAG
  ATGACTGTGAAGATAGTGTGCCGGTGCCTGGCTGACCTGCGGGACTACTGCCAGCCTCATGCCCCAGGGG
  CCCTGCTGAAGGCGGCCTTCATCTGTGCAGGGATCGTGCATGTCCACTCGGAACTCCAGCTGAGTGAGCA
  GCTGCTCCGCACCTTCGGGGGCGGCTTTGAGCTGCACACCTGGTCTGAGCTGCCCCACGGCTCTGGCCTG
  GGCACCAGCAGCATCCTGGCAGGCACTGCCCTGGCTGCCTTGCAGCGAGCCGCAGGCCGGGTGGTGGGCA
  CGGAAGCCCTGATCCACGCAGTGCTGCACCTGGAGCAGGTGCTCACCACTGGAGGTGGCTGGCAGGACCA
  AGTAGGTGGCCTAATGCCTGGCATCAAGGTGGGGCGCTCCCGGGCTCAGCTGCCACTGAAGGTGGAGGTA
  GAAGAGGTCACGGTGCCTGAGGGCTTTGTCCAGAAGCTCAATGACCACCTGCTCTTGGTGTACACTGGCA
  AGACCCGCCTGGCTCGGAACCTGCTGCAGGATGTGCTGAGGAGCTGGTATGCCCGACTTCCTGCTGTGGT
  GCAGAATGCCCACAGCCTGGTACGGCAAACTGAGGAGTGTGCTGAAGGCTTCCGCCAAGGAAGCCTGCCT
  CTGCTGGGCCAGTGCCTGACCTCGTACTGGGAGCAGAAGAAGCTCATGGCTCCAGGCTGTGAGCCCCTGA
  CTGTGCGGCGTATGATGGATGTCCTGGCCCCCCACGTGCATGGCCAGAGCCTGGCTGGGGCAGGCGGTGG
  AGGCTTTCTCTATCTGTTGACCAAGGAGCCACAGCAAAAGGAGGCCTTGGAGGCGGTGCTGGCCAAGACC
  GAGGGCCTTGGGAATTACAGCATCCACCTGGTTGAAGTGGACACTCAGGGCCTGAGCCTGAAGCTGCTGG
  GGACCGAGGCCTCAACCTGTTGCCCTTTCCCATGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_145059 unedited
  CATTTCCCCGCCCGTTGACGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG
  CAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGC
  GAATTCGGCACGAGGGAGCGCCGGGCGACGGCAGGAAGCCCCTCCGCTTGGCCAGAATGG
  AGCAGCCGAAGGGAGTTGATTGGACAGTCATCATCCTGACCTGCCAGTACAAGGACAGTG
  TCCAGGTCTTTCAGAGAGAACTGGAAGTGCGGCAGAAGCGGGAGCAGATCCCTGCTGGGA
  CGCTGTTACTGGCCGTGGAGGACCCAGAGAAGCGTGTGGGCAGCGGAGGAGCCACCCTCA
  ACGCCCTGCTGGTGGCTGCTGAACACCTGAGTGCCCGGGCAGGCTTCACTGTGGTCACAT
  CCGATGTCCTGCACTCGGCCTGGATCCTCATTCTGCACATGGGTCGAGACTTCCCCTTTG
  ATGACTGTGGCAGGGCTTTCACCTGCCTCCCCGTGGAGAACCCCGAGGCCCCCGTGGAAG
  CCTTGGTCTGCAACCTGGACTGCCTGCTGGACATCATGACCTATCGGCTGGGCCCGGGCT
  CCCCGCCAGGCGTGTGGGTCTGCAGCACCGACATGCTGCTGTCTGTTCCTGCAAATCCTG
  GTATCAGCTGNGACAGCTTCCGGNGAGCCAGAGTGATCGCCCTCCCAGGGAGCCTGGCCT
  ACGCTCAGAATCATGGCGTCTACCTAACTGACCTCCAGGGCCTTGTTTATGGACATTTAC
  TACCAGNGCACTGAGGCAGAGTTCAGCGGTGTGTCCGGCCTGAGGGGCGGATGCCCTGGC
  TCTTGGGGGTGACTTCTCTCTGTGGAGATGCCGAGCGCCTCTACCACCCCGTGAGCCCGC
  CCTGGATGCTGCACTACCTAGCATGNACTCGGAGCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_145059
• ORF Size: 3255 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_145059.2, NP_659496.2
• RefSeq Size: 3923
• RefSeq ORF: 3255
• Locus ID: 197258
• Domains: GHMP_kinases
• Protein Families: Druggable Genome
• Protein Pathways: Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Metabolic pathways
• Gene Summary: The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008]