FKBP2 (M65128) Human Untagged Clone

CAT#: SC105971

(untagged)-Human rapamycin-binding protein (FKBp-13) mRNA, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FKBP2
• Synonyms: FKBP-13|PPIase
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for M65128 edited
  ATGAGGCTGAGCTGGTTCCGGGTCCTGACAGTACTGTCCATCTGCCTGAGCGCCGTGGCC
  ACGGCCACGGGGGCCGAGGGCAAAAGGAAGCTGCAGATCGGGGTCAAGAAGCGGGTGGAC
  CACTGTCCCATCAAATCGCGCAAAGGGGATGTCCTGCACATGCACTACACGGGGAAGCTG
  GAAGATGGGACAGAGTTTGACAGCAGCCTGCCCCAGAACCAGCCCTTTGTCTTCTCCCTT
  GGCACAGGCCAGGTCATCAAGGGCTGGGACCAGGGGCTGCTGGGGATGTGTGAGGGGGAA
  AAGCGCAAGCTGGTGATCCCATCCGAGCTAGGGTATGGAGAGCGGGGAGCTCCCCCAAAG
  ATTCCAGGCGGTGCAACCCTGGTGTTCGAGGTGGAGCTGCTCAAAATAGAGCGACGAACT
  GAGCTGTAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for M65128 unedited
  TCATATTTTGTAATACGACTCACTATAGGGCGGCCGCGAAATTCGCACCAGGCGTGTGGC
  CGCGGGTTTCGCACGGTCCAATAAGGGAGGGCGGCGTGGCCCGGCCTGGTAGCGACGAGG
  TACGCGCCTGCGCAGAGGCGGCAGCACCACCGGGGTTGACTCCGGGGGCGCGGCGAGGAG
  AGACATGAGGCTGAGCTGGTTCCGGGTCCTGACAGTACTGTCCATCTGCCTGAGCGCCGT
  GGCCACGGCCACGGGGGCCGAGGGCAAAAGGAAGCTGCAGATCGGGGTCAAGAAGCGGGT
  GGACCACTGTCCCATCAAATCGCGCAAAGGGGATGTCCTGCACATGCACTACACGGGGAA
  GCTGGAAGATGGGACAGAGTTTGACAGCAGCCTGCCCCAGAACCAGCCCTTTGTCTTCTC
  CCTTGGCACAGGCCAGGTCATCAAGGGCTGGGACCAGGGGCTGCTGGGGATGTGTGAGGG
  GGAAAAGCGCAAGCTGGTGATCCCATCCGAGCTAGGGTATGGAGAGCGGGGAGCTCCCCC
  AAAGATTCCAGGCGGTGCAACCCTGGTGTTCGAGGTGGAGCTGCTCAAAATAGAGCGACG
  AACTGAGCTGTAACCAGACTGGGGAGGGGCAGGGNGGAGAGGCCCCCATCANGGACCAGA
  CTGTTCCAAANAAAAAACAAAAAACAAAAACAAACAAAAAAACACTTAAAAGCCAAAAAA
  AAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAACAG
  ATCCCCGGTGGCATCCCTGTGACCCCTNCCCAGTGCCTCTTCTGGCCCTGGNAAGTTGCA
  CTTCAGTGCCCACAGCCTTGTNCTAAATAATTAAGTTGCATCATTTTGTCTGACTAGGTG
  TCCTCATATATATGGGTGAGGGGGGGGGGTGTTTNNNNAAAAGGGCAANTTTGGAAAAAA
  ACCTTTGGGGCTGGGGGGTATTTGGAAACCACTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for M65128 unedited
  GTACAGCTATGNNACCGCGGCCGCATNCTAGNGATCGGTTTTTTTTTTTTTTTTTTTTTG
  GCTTTTAAGTGTTTTTTTGTTTGTTTTTGTTTTTTGTTTTTTTTTTGGAACAGTCTGGTC
  CCTGATGGGGGCCTCTCCCCCTGCCCCTCCCCAGTCTGGTTACAGCTCAGTTCGTCGCTC
  TATTTTGAGCAGCTCCACCTCGAACACCAGGGTTGCACCGCCTGGAATCTTTGGGGGAGC
  TCCCCGCTCTCCATACCCTAACTCGGATGGGATCACCAGCTTGCGCTTTTCCCCCTCACA
  CATCCCCAGCAGCCCCTGGTCCCAGCCCTTGATGACCTGGCCTGTGCCAAGGGAGAAGAC
  AAAGGGCTGGTTCTGGGGCAGGCTGCTGTCAAACTCTGTCCCATCTTCCAGCTTCCCCGT
  GTAGTGCATGTGCAGGACATCCCCTTTGCGCGATTTGATGGGACAGTGGTCCACCCGCTT
  CTTGACCCCGATCTGCAGCTTCCTTTTGCCCTCGGCCCCCGTGGCCGTGGCCACGGCGCT
  CAAGCAGATGGACAGTACTGTCAGGACCCGGAACCAGCTCAGCCTCATGTCTCTCCTCGC
  CGCGCCCCCGGAGTCAACCCCGGTGGTGCTGCCGCCTCTGCGCAGGCGCGTCCTCGTCGC
  TACCAGGCCGGGCCACGCCGCCCTCCCTTATTGGACCGTGCGAAACCCGCGGCCACACGC
  CCTGGTGCCGAATTCGCGGCCGCCCTATAGTGAGTCGTATTACAAAATTCTGACGGTTCA
  CTAAACGAGCTCTGCTTATATAGACCTNCCACCGTACACGCCTACCGGCCATTTGCGTCA
  ACGGGGGCGGGGTTATTACGACATTTTGGAAAGTCCCGTTGATTTTGGTGCCCAACAAAC
  TCCCATTGACGTCAATGGGGTGGAGACTTGGAAATCCC
  
• Restriction Sites: NotI-NotI
• ACCN: M65128
• Insert Size: 800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: M65128.1, AAA58473.1
• RefSeq Size: 550 bp
• RefSeq ORF: 426 bp
• Locus ID: 2286
• Cytogenetics: 11q13.1
• Domains: FKBP
• Protein Families: Druggable Genome
• Gene Summary: 'The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]'