PCDHGA2 (NM_032009) Human Untagged Clone

CAT#: SC106781

PCDHGA2 (untagged)-Human protocadherin gamma subfamily A, 2 (PCDHGA2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHGA2
• Synonyms: PCDH-GAMMA-A2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC106781 sequence for NM_032009 edited (data generated by NextGen Sequencing)
  ATGGCGGCTCTGCAAAAGTTGCCACACTGCAGAAAGCTGGTCCTGCTGTGCTTCCTTTTG
  GCGACCCTGTGGGAGGCCAGGGCCGGGCAGATTCGCTATTCTGTGCGGGAAGAGATCGAC
  AGAGGCTCCTTCGTAGGCAACATCGCCAAGGACTTGGGTTTGGAGCCCCTGGCACTGGCA
  GAGCAGGGAGTCCGCATCGTCTCCAGAGGTAGGTCCCAGCTCTTTGCTCTGAACCCGCGA
  AGCGGCAGCTTGGTCACTGCGAACAGGATAGACCGGGAGGAGCTCTGCGCTCAGAGCGCA
  CCCTGTCTGTTGAATTTTAACATTCTGCTGGAGGATAAATTGACTATTTATTCAGTAGAG
  GTGGAAATAACAGATATTAACGATAATGCCCCTCGCTTTGGAGTAGAGGAACTGGAGCTA
  AAAATCAGTGAAACCACTACGCCAGGATTCCGGATTCCTCTTAAGAATGCGCATGATGCA
  GACGTAGGTGAGAACGCCCTTCAGAAGTACGCACTCAACCCAAATGACCACTTCTCCCTG
  GACGTGCGAAGGGGAGCTGATGGGAACAAGTACCCAGAACTGGTGCTGGAGCGCTCTCTG
  GACCGCGAGGAAGAGGCTGTTCACCACCTCGTTCTCGTGGCTTCTGATGGGGGTGACCCA
  GTGCTATCTGGCACCTCCCGCATCTGCGTGAAGGTCCTGGATGCGAACGACAATGCGCCT
  GTTTTTACACAGCCCGAGTACCGCATAAGCATTCCGGAGAATACGCTCGTGGGCACCCGG
  ATACTCACGGTGACCGCCACTGACGCAGATGAGGGCTACTACGCTCWAGTGGTATATTTT
  CTAGAGAAAAGCCCTGGAGAAACCTCAGAGGTATTTGAGCTTAAGTCAACATCTGGAGAA
  CTGACAATCATAAAAGATCTAGATTATGAGGATGCTACATTCCATGAAATTGATATTGAA
  GCTCAGGATGGTCCGGGCCTTCTAACCAGAGCGAAGGTTATCGTCACGGTTCTGGATGTG
  AATGACAATGCCCCAGAATTTTACATGACATCTGCTACTAGCTCAGTTTCTGAAGACTCT
  CTTCCAGGAACCATAATTGGGCTTTTTAATGTACATGATAGAGACTCTGGGCAGAACGCA
  TTCACCACCTGTTCACTCCCCGAGGATCTTCCTTTTAAGTTAGAAAAGTCAGTAGACAAT
  TACTACCGACTGGTTACAACCAGAGCCCTTGACAGGGAACAGTTTTCCTTTTACAACATC
  ACTCTAACCGCTAAAGATGGAGGGAACCCCTCCCTGTCCACGGATGCTCACATTTTGCTC
  CAGGTGGCAGACATCAACGACAACGCACCCGCCTTCTCCCGCACATCCTACTCCACCTAC
  ATTCCCGAAAACAACCCCAGAGGAGCCTCTGTCTTCTCAGTGACGGCCCATGACCCCGAC
  AGCAACGACAATGCTCATGTAACTTACTCTTTCGCGGAGGACACTGTTCAGGGGGCACCC
  TTATCCTCTTACATCTCTATCAACTCCGACACTGGAGTACTCTATGCACTGCGCTCCTTT
  GATTATGAGCAGTTGCGAGACTTGCAAGTGTGGGTGATAGCGCGGGACAGCGGGAACCCT
  CCACTCAGTAGCAATGTATCATTAAGCCTGTTCGTGCTGGACCAGAACGACAACGCGCCC
  GAGATCCTGTACCCTGCCTTCCCCACAGACGGTTCCACTGGCGTGGAGCTGGCGCCCCGC
  TCCGCAGAGCCCGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACAGAGACTCGGGCCAG
  AACGCCTGGCTGTCTTACCACCTGCTCAAGGCCAGCGAGCCGGGACTCTTCTCGGTGGGT
  CTGCACACGGGCGAGGTGCGCACGGCGCGAGCCCTGCTGGACAGAGACGCGCTCAAGCAG
  AGCCTCGTGGTGGCCATCCAGGACCACGGCCAGCCCCCTCTCTCCGCCACTGTCACGCTC
  ACCGTGGCCGTGGCCGACAGGATCCCCGACATCCTGGCCGACCTGGGCAGCCTCGAGCCC
  TCCGCCATACCCAACGATTCGGACCTCACTCTGTACCTGGTGGTGGCGGTGGCCGCGGTC
  TCCTGCGTCTTCCTGGCCTTCGTCATCGTGTTGCTGGCGCACAGGCTGCGGCGCTGGCAC
  AAGTCACGCCTGCTGCAGGCTTCAGGAGGCAGCTTGACAGGCATGCAGAGCTCGCACTTT
  GTGGGCGTGGACGGGGTTCGGGCTTTCCTGCAGACCTATTCCCACGAGGTCTCCCTCACT
  GCGGACTCGCGGAAGAGCCACCTGATTTTCCCCCAGCCCAACTATGCGGACACGCTCATC
  AGCCAGGAGAGCTGTGAGAAAAAGGATTTTTTATCAGCGCCTCAATCTCTACTCGAAGAA
  GAAAGAGAAGAAACGTTTTCTCAGGTAATCTATCTTTTCACAACATACGTACTAGCTAGT
  TTGCTGAAGTAA
  
  Clone variation with respect to NM_032009.1
  827 a=>w
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_032009 unedited
  GTCAAATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACCAGCCCAGCACAAG
  GGGGTGGAGGTTTGGCCCTAAAGCTTCAGGACACCAAAGAAATTCAGTCGAACAGCCCAC
  CAGTTCTCTCCATAGGGACCTGGGTCCCGTGAATGCTGGTTATCTCACACCCTGAGGAAT
  AAAGATTGGAATCCGCACTGGATGCTGGAAGTTGACTCGGAGAAAATTGCGACAGGAGGG
  AAATGGCGGCTCTGCAAAAGTTGCCACACTGCAGAAAGCTGGTCCTGCTGTGCTTCCTTT
  TGGCGACCCTGTGGGAGGCCAGGGCCGGGCAGATTCGCTATTCTGTGCGGGAAGAGATCG
  ACAGAGGCTCCTTCGTAGGCAACATCGCCAAGGACTTGGGTTTGGAGCCCCTGGCACTGG
  CAGAGCAGGGAGTCCGCATCGTCTCCAGAGGTAGGTCCCAGCTCTTTGCTCTGAACCCGC
  GAAGCGGCAGCTTGGTCACTGCGAACAGGATAGACCGGGAGGAGCTCTGCGCTCAGAGCG
  CACCCTGTCTGTTGAATTTTAACATTCTGCTGGAGGATAAATTGACTATTTATTCAGTAG
  AGGTGGAAATAACAGATATTAACGATAATGCCCCTCGCTTTGGAGTAGAGGAACTGGAGC
  TAAAAATCAGTGAAACCACTACGCCAGGATTNCGGATTCCTCTTAAGATGCGCATGATGC
  AGACGTANGTGAGAACGCCCTTCAGAAGTACGCACTCAACCCAAATGAACCACTTCTCCT
  GGACGTGCGAAGGGGAGCTGATGGGAACAGTACCAGAACTGGGTGCTGACGCTCTCTGGA
  CCCGAGAAGNAGCTGNTACCACCTGNTCTCGTGCTCTGATGGGGGTGACCATGCTTCTGC
  ACTCCGCACTGCNTGAAGTNNCTGATCGACACATGCGCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_032009 unedited
  NNNTTCCTCGGTGNACCCGGCCGCATTCTANGATCGGTTTTTTTTTTTTTTTTTTTTTTT
  TGAAAACAGCCATATTTATACATTATATTTCTTTAAGTTTGTTCTTGGTGACCTGATAAC
  TTAGTTTCGATATTTGTTGTTATTTAATATTCATTAAACAAACACATAATTAGGCATCAG
  ACAATATGTTTGGGGATTTAAGGTGAACAATATAGACACAGTAGCTTCCTTCACAGAGAT
  TATAAGGATATAAAAGCAAACAGGGAATTGCAGTGTACTGAGATAATTACCATAATGGGA
  GAAGCCAAGGGGGTTAGGGGGGCCTTCAATTGGGCCTTTAATGTTAGCAAACGCTTTCCC
  AGGAAACATGAAAGGAGCGGATCAGTGAAAAGGCCTGGATGTGGGAGAGAACACTCTGAC
  AATGCCTAGGTGCGACAGAGAAATCACACACCTTCAGGGTACTGAAAGAAGGTATCTTCG
  TTTACCCTATACCGCTCCGACGTCACTCTCCACCCACCTGTGTTATTCCCCCCCGCCTCT
  CCTTCTCCACCCCCCCTACTCTTACCTTTTAACCTCTTCCACCAGTCACCTATTCGCCTC
  CATATCCCCCTCTCCCCCCGCCTCCTCATCCCCCTCTCACACTCTCCGCCCCTCTCTCAC
  AGCCCAGACCTCACCGTATCTCCTACCTCTGTCCCAAGTCTCTGTATCGCTTAGTGCACT
  AGTTATCTATTACTCGCGCGCGCCTTCCTACCCGCTCCCTTCGTTCTCCTTCTCATTCAC
  TCCCGCGCCACGGACGCACCCCTATACCCTGCCCAATTACGAAAACATATTCCATATCGC
  CGCTCTCTCTTTTTTCCCTTCACTCTTCTTGCCTCCCACTACCCTTTCTTGCTCATTTCC
  TCTCCACCACTTACCCACTTCCCCATTN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_032009
• ORF Size: 2472 bp
• Insert Size: 3920
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_032009.1, NP_114398.1
• RefSeq Size: 2657
• RefSeq ORF: 2472
• Locus ID: 56113
• Domains: CA
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes the shorter isoform (2). This short variant is represented based on data in PMID:10380929.