PNPO (NM_018129) Human Untagged Clone

CAT#: SC108655

PNPO (untagged)-Human pyridoxamine 5'-phosphate oxidase (PNPO)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PNPO
• Synonyms: HEL-S-302; PDXPO
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108655 sequence for NM_018129 edited (data generated by NextGen Sequencing)
  ATGACGTGCTGGCTGCGGGGCGTCACGGCGACGTTCGGGCGACCTGCCGAGTGGCCAGGC
  TACCTCAGTCACCTGTGTGGTCGCAGTGCTGCCATGGACCTGGGACCCATGCGCAAGAGT
  TACCGCGGGGACCGAGAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAA
  CAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCC
  ATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAG
  GGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCAAAAAGGAAAAGAG
  CTGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCACTTAACCGTCAGGTG
  CGTGTGGAAGGCCCTGTGAAGAAACTGCCTGAGGAGGAGGCTGAGTGCTACTTCCACTCC
  CGCCCCAAGAGCAGCCAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGAT
  CGGGAGTATCTAAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTG
  CCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAA
  GGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGAT
  TCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCA
  CCTTAA
  
  Clone variation with respect to NM_018129.3
  347 g=>a;552 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018129 unedited
  GGTCACCATTTTGTAATACGACTCACTTATAGGGCGGCCGCGATTCGGCACGAGGCTCAA
  AGGAACCCAGTGCCGGGCCACAGCCGGGTCACGTGGCCGGCGGCCCCCCATGACGTGCTG
  GCTGCGGGGCGTCACGGCGACGTTCGGGCGACCTGCCGAGTGGCCAGGCTACCTCAATCA
  CCTGTGTGGTCGCAGTGCTGCCATGGACCTGGGACCCATGCGCAAGAGTTACCGCGGGGA
  CCGAGAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCACTGAAACAGTTTGCTGC
  CTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGC
  TACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAA
  AGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCAAAAAGGAAAAGAGCTGGACTCTAA
  TCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCACTTAACCGTCAGGTGCGTGTGGAAGG
  CCCTGTGAAGAAACTGCCTGAGGAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAGAG
  CANCCAAATCGGGGCTGTGGTCAGCCACCAAAGTTCTGTGATCCCTGATCGGGAGTATCT
  AATAAAGAAACATGAGGAACTGGAACAGCTCTACCACGATCACAGAGTGCCCAAGCCAAA
  ATCCTGTGGTGGCTATGTCCTGTCCCCTCACGTGATGGAGTTCTGGCCAGTTCAAACCTC
  CCGCCTGCATGACCGGATAATCTTTCCGCGGTGCCTACCCCAGGAAATTCCTCTTTGGGG
  CCCATTGACCACCCTGGGGAGAACACTGGCTCTTAGAGAGACTTGCCCCTAACTTTGGGC
  ACTGCTTGCCCCAATGGAGCTTGGCTCGGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_018129 unedited
  GGGGGGCGGGGTCCGCACAACCACACTAAACAAAAGGANGTTGGTGAAACTATAAACCCT
  TTTTTGTTGGAAATGTCTGCCTCACATACACAGCAGTTTCCATCTTAAAACATACATAGT
  AAAGCTCGATTAAAATCTTCCTGTCCTATTGGTACCAGCACATGAAGCCCTTCTACAAAA
  TTCCTGACGGACTGGGAATAAAAATTCCTAGTGACAGCCCACTCCTTCTCAGGCAGGTGC
  GATTGCCTGAAATCTCTCCCAATATCGACATGAAACCTGCTTCCCTGTAACTCCCCTGTA
  ATTATGTGGGTCCCTTGTAGCCACAGAAAAGGCAGTAATCAGTATGGGAAGTGCTTTAAA
  AACTTTCTATCCCGGTCAAGCGTGGTGGCTCATGTCTGTAATCCCAGCACTTTGGGAGGT
  CCAGGTGGGCATTATCACTTTATGTCATGAGTTGGAGACCACACTGGTCACCATAATGAA
  ACCCTCGTCTCCTGGGTGCGGTGGCTAATGCCTGTAATTCCAACCCTTTCGGTAGGCTGA
  GGTGGGCGGATCACATGGTCAAAAGATGGATACATCCTGGCCTACATGGTGAAACCTCTT
  TTCTACTAAACATACAACATTTAACTGGTTCTCGTGGCTTTTGTCCTTTATTTCTATCTA
  CTTGGTGATGTCTTGGCCGCGCATAATTGCTTTGAACACTGGCGAGGCATACGTTGCCAT
  CGATCTCCCCTACACCCCTTTGTACTCTCCCTCTGGGAGGACAGACAGTAAACTTCTTCT
  TTTTAAATAATAAGAATTTGTACACACTATTATTTATAACTTTCCTTTCTTCCCCTCATT
  CCTTTTTCTTACCTTTGCTCCCCCCTCACTAAATTTCTTTCTTCCCTTTCTCTATTATAC
  TTACCCCCACATTGCCACCTCCTCTCCTGTTATATTTGACCTCTTCTAAGCGCGTGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_018129
• ORF Size: 786 bp
• Insert Size: 2380
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_018129.1, NP_060599.1
• RefSeq Size: 2396
• RefSeq ORF: 786
• Locus ID: 55163
• Domains: Pyridox_oxidase
• Protein Pathways: Metabolic pathways, Vitamin B6 metabolism
• Gene Summary: The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq, Oct 2008]