DPP1 (CTSC) (NM_001814) Human Untagged Clone

CAT#: SC109064

CTSC (untagged)-Human cathepsin C (CTSC), transcript variant 1


  "NM_001814" in other vectors (6)

Reconstitution Protocol

SC109064 is the updated version of SC125405.

USD 780.00

In Stock*

Size
    • 10 ug

Product Images

Other products for "CTSC"

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CTSC
Synonyms CPPI; DPP-I; DPP1; DPPI; HMS; JP; JPD; PALS; PDON1; PLS
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC109064 sequence for NM_001814 edited (data generated by NextGen Sequencing)
ATGGGTGCTGGGCCCTCCTTGCTGCTCGCCGCCCTCCTGCTGCTTCTCTCCGGCGACGGC
GCCGTGCGCTGCGACACACCTGCCAACTGCACCTATCTTGACCTGCTGGGCACCTGGGTC
TTCCAGGTGGGCTCCAGCGGTTCCCAGCGCGATGTCAACTGCTCGGTTATGGGACCACAA
GAAAAAAAAGTAGTGGTGTACCTTCAGAAGCTGGATACAGCATATGATGACCTTGGCAAT
TCTGGCCATTTCACCATCATTTACAACCAAGGCTTTGAGATTGTGTTGAATGACTACAAG
TGGTTTGCCTTTTTTAAGTATAAAGAAGAGGGCAGCAAGGTGACCACTTACTGCAACGAG
ACAATGACTGGGTGGGTGCATGATGTGTTGGGCCGGAACTGGGCTTGTTTCACCGGAAAG
AAGGTGGGAACTGCCTCTGAGAATGTGTATGTCAACACAGCACACCTTAAGAATTCTCAG
GAAAAGTATTCTAATAGGCTCTACAAGTATGATCACAACTTTGTGAAAGCTATCAATGCC
ATTCAGAAGTCTTGGACTGCAACTACATACATGGAATATGAGACTCTTACCCTGGGAGAT
ATGATTAGGAGAAGTGGTGGCCACAGTCGAAAAATCCCAAGGCCCAAACCTGCACCACTG
ACTGCTGAAATACAGCAAAAGATTTTGCATTTGCCAACATCTTGGGACTGGAGAAATGTT
CATGGTATCAATTTTGTCAGTCCTGTTCGAAACCAAGCATCCTGTGGCAGCTGCTACTCA
TTTGCTTCTATGGGTATGCTAGAAGCGAGAATCCGTATACTAACCAACAATTCTCAGACC
CCAATCCTAAGCCCTCAGGAGGTTGTGTCTTGTAGCCAGTATGCTCAAGGCTGTGAAGGC
GGCTTCCCATACCTTATTGCAGGAAAGTACGCCCAAGATTTTGGGCTGGTGGAAGAAGCT
TGCTTCCCCTACACAGGCACTGATTCTCCATGCAAAATGAAGGAAGACTGCTTTCGTTAT
TACTCCTCTGAGTACCACTATGTAGGAGGTTTCTATGGAGGCTGCAATGAAGCCCTGATG
AAGCTTGAGTTGGTCCATCATGGGCCCATGGCAGTTGCTTTTGAAGTATATGATGACTTC
CTCCACTACAAAAAGGGGATCTACCACCACACTGGTCTAAGAGACCCTTTCAACCCCTTT
GAGCTGACTAATCATGCTGTTCTGCTTGTGGGCTATGGCACTGACTCAGCCTCTGGGATG
GATTACTGGATTGTTAAAAACAGCTGGGGCACCGGCTGGGGTGAGAATGGCTACTTCCGG
ATCCGCAGAGGAACTGATGAGTGTGCAATTGAGAGCATAGCAGTGGCAGCCACACCAATT
CCTAAATTGTAG

Clone variation with respect to NM_001814.4
>OriGene 5' read for NM_001814 unedited
AACCTCGGGATTTGTAAACGACTCCTGAGGGCGGAAAACCCTTCGCACGAGGGCTCGGCT
TCCTGGTAATTCTTCACCTCTTTTCTCAGCTCCCTGCAGCATGGGTGCTGGGCCCTCCTT
GCTGCTCGCCGCCCTCCTGCTGCTTCTCTCCGGCGACGGCGCCGTGCGCTGCGACACACC
TGCCAACTGCACCTATCTTGACCTGCTGGGCACTTGTGTCTTCCAGGTGGGCTCCAGCGG
TTCCCAGCGCGATGTCAACTGCTCGGTTATGGGACCACAAGAAAAAAAAGTAGTGGTGTA
CCTTCAGAAGCTGGATACAGCATATGATGACCTTGGCAATTCTGGCCATTTCACCATCAT
TTACAACCAAGGCTTTGAGATTGTGTTGAATGACTACAAGTGGTTTGCCTTTTTTAAGTA
TAAAGAAGAGGGCAGCAAGGTGACCACTTACTGCAACGAGACAATGACTGGGTGGGTGCA
TGATGTGTTGGGCCGGAACTGGGCTTGTTTCACCGGAAAGAAGGTGGGAACTGCCTCTGA
GAATGTGTATGTCAACACAGCACACCTTAAGAATTCTCAGGAAAAGTATTCTAATAGGCT
CTACAAGTATGATCACAACTTTGTGAAAGCTATCAATGCCATTCAGAAGTCTTGGACTGC
AACTACATACATGGAATATGAGACTCTTACCCTGNGAGATATGATTAGGAGAAGTGGTGG
CCACAGTCGAAAAATCCCAAGGCCCAAACCTGCACCACTGACTGCTGAAATACAGCAAAA
GATTTTGCATTTGCCAACATCTTGNGACTGGAGAAATGTTCATGGTATCAATTTTGTCAG
TCCTGTTCGAAACCAAGCATCCTGTGGCAGCTGCTACTCATTTGCTTCTATGGGTATGCT
AGAAGCGAGC
>OriGene 3' read for NM_001814 unedited
CGCGGCACGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGCAGTTATTTTTAAAACT
TTATTTTAAAAATATGAGCATCTATTTTAAAAGTTTTGATAATTATTGCCATTATTTTCT
TGTGATTGGTACAATTTAAAAATAAGTCTATGTTTTCACATTGATTTTAAAAAATATAGC
ATGTTTGAATTACAAATGATTAAGCAAACTCTATTACTTCATAGCTGACCATCTTCCAGA
AAATTCCCACTTAATTGAATACTTAGAAAAAAATGGCCAGTGGCCGATTGAAAGGTATAT
TAAAATTAAGGGCAGTTTTAATTCTGAAGACAAATATCTTCATGGAAATCTATTTGTAAG
CTTCTGAGATTGCTGCTGAAAGTCTACAGTCTGTGAATATACCAATTCCCCTTTACAACT
GATGCAGATCATTATGAAATACTGGAAGGCATACCCTACAATTTAAGAATTGGTGTGGCT
GCCACTGCTATGCTCTCAATTGCACACTCATCAGTTCCTCTGCGGATCCGGAAGTAGCCA
TTCTCACCCCAGCCGGTGCCCCAGCTGTTTTTAACAATCCAGTAATCCATCCCAGAGGCT
GAGTCAGTGCCATAGCCCACAAGCAGAACAGCATGATTAGTCAGCTCAAAGGGGTTGAAA
GGGTCTCTTAGACCAGTGTGGTGGTAGATCCCCTTTCTGTAGTGGAGGAAGTCATCATAT
ACTTCAAAAGCAACTGCCATGGGCCCATGATGGACCAACTCAAGCTTCATCAGGGCTTCA
TTGCAGCCTCCATAGAAACCTCCTACATAGTGGTACTCAGAGGGAGTATAACGAAAGCAG
TCTTNCTTTCATTTTGCATGGAGAATCANTGCCTGTGTANGGGAAAGCAGCTTCTTCACC
AGCCCAAATCTGGNCGTACTTNCTGCATAAGGTATGGAAGCCGCCTCACAGCCTGAGCTA
CTG
Restriction Sites NotI-NotI     
ACCN NM_001814
Insert Size 1960 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001814.2, NP_001805.1
RefSeq Size 1904 bp
RefSeq ORF 1392 bp
Locus ID 1075
Cytogenetics 11q14.2
Domains Pept_C1
Protein Families Druggable Genome, Protease
Protein Pathways Lysosome
Gene Summary 'This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. [provided by RefSeq, Nov 2015]'
Transcript Variant: This variant (1) represents the shortest transcript and encodes the longest isoform (a).

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.