EED (NM_152991) Human Untagged Clone

CAT#: SC109981

EED (untagged)-Human embryonic ectoderm development (EED), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EED
• Synonyms: COGIS; HEED; WAIT1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_152991, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCCGAGAGGGAAGTGTCGACTGCGCCGGCGGGAACAGACATGCCTGCGGCCAAGAAGCAGAAGCTGA
  GCAGTGACGAGAACAGCAATCCAGACCTCTCTGGAGACGAGAATGATGACGCTGTCAGTATAGAAAGTGG
  TACAAACACTGAACGCCCTGATACACCTACAAACACGCCAAATGCACCTGGAAGGAAAAGTTGGGGAAAG
  GGAAAATGGAAGTCAAAGAAATGCAAATATTCTTTCAAATGTGTAAATAGTCTCAAGGAAGATCATAACC
  AACCATTGTTTGGAGTTCAGTTTAACTGGCACAGTAAAGAAGGAGATCCATTAGTGTTTGCAACTGTAGG
  AAGCAACAGAGTTACCTTGTATGAATGTCATTCACAAGGAGAAATCCGGTTGTTGCAATCTTACGTGGAT
  GCTGATGCTGATGAAAACTTTTACACTTGTGCATGGACCTATGATAGCAATACGAGCCATCCTCTGCTGG
  CTGTAGCTGGATCTAGAGGCATAATTAGGATAATAAATCCTATAACAATGCAGTGTATAAAGCACTATGT
  TGGCCATGGAAATGCTATCAATGAGCTGAAATTCCATCCAAGAGATCCAAATCTTCTCCTGTCAGTAAGT
  AAAGATCATGCTTTACGATTATGGAATATCCAGACGGACACTCTGGTGGCAATATTTGGAGGCGTAGAAG
  GGCACAGAGATGAAGTTCTAAGTGCTGATTATGATCTTTTGGGTGAAAAAATAATGTCCTGTGGTATGGA
  TCATTCTCTTAAACTTTGGAGGATCAATTCAAAGAGAATGATGAATGCAATTAAGGAATCTTATGATTAT
  AATCCAAATAAAACTAACAGGCCATTTATTTCTCAGAAAATCCATTTTCCTGATTTTTCTACCAGAGACA
  TACATAGGAATTATGTTGATTGTGTGCGATGGTTAGGCGATTTGATACTTTCTAAGTCTTGTGAAAATGC
  CATTGTGTGCTGGAAACCTGGCAAGATGGAAGATGATATAGATAAAATTAAACCCAGTGAATCTAATGTG
  ACTATTCTTGGGCGATTTGATTACAGCCAGTGTGACATTTGGTACATGAGGTTTTCTATGGATTTCTGGC
  AAAAGATGCTTGCATTGGGCAATCAAGTTGGCAAACTTTATGTTTGGGATTTAGAAGTAGAAGATCCTCA
  TAAAGCCAAGTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152991 unedited
  GGATTTTGTAATACGACTTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGAAGCCGCG
  CGGGAGGGCGCGCGCGCGCGCCCCTTTTTCAGCAGTGTGGCGGGGTCGCACGCACGCCCG
  CCTCGGCGGCTGGGCGCGATTTGCGACAGTGGGGGGGGCGGTGGAGGTGGCGGCGGCAGC
  GGCAACTTTGCGGCAAGCTCGGGCCGGGCTTGCTTGACGGCGGTGTGGCGGAGGCCCCGC
  CCCAGGCGGCAGGAACCTGGAGGGAGGCGGAGGAATATGTCCGAGAGGGAAGTGTCGACT
  GCGCCGGCGGGAACAGACATGCCTGCGGCCAAGAAGCAGAAGCTGAGCAGTGACGAGAAC
  AGCAATCCAGACCTCTCTGGAGACGAGAATGATGACGCTGTCAGTATAGAAAGTGGTACA
  AACACTGAACGCCCTGATACACCTACAAACACGCCAAATGCACCTGGAAGGAAAAGTTGG
  GGAAAGGGAAAATGGAAGTCAAAGAAATGCAAATATTCTTTCAAATGTGTAAATAGTCTC
  AAGGAAGATCATAACCAACCATTGTTTGGAGTTCAGTTTAACTGGCACAGTAAAGAAGGA
  GATCCATTAGTGTTTGCAACTGTAGGAAGCAACAGAGTTACCTTGTATGAATGTCATTCA
  CAAGGAGAAATCCGGTTGTTGCAATCTTACGTGGATGCTGATGCTGATGAAAACTTTTAC
  ACTTGTGCATGGACCTATGATAGCAATACGAGCCATCCTCTGCTGGCTGTAGCTGGATCT
  AGAGGCATAATTAGGATAATAAATCCTATNACAATGCAGTGTATAAAGCACTATGTTGGC
  CCATGAAATGCTANTCATGAGCTGAAATTCATNNCAGAGATCCAAATCTCTNCTGTCAGT
  AGTAAAAGATCATGCTTACGATNATGGAATATCCAGACGACACTCTGTGGCATATTNGNA
  GCGTANAAGGCACCNAATGAGTNCTAGTGCTGATATGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_152991 unedited
  AGGANAGCACTGGGGNAGGGTCAAGGGATGCCACCCGGGTATCTGTTCAGGAAAACAGCT
  ATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTACAAAAATAAATTT
  TTATTAAAAGCAGTAGAGTCTGAGCAGGAAGACAGTACAAAGAATGTAAACAATGTAAAC
  ATCACTACATTCAGCTCAGCCTGATTGAATGCTGAAAGACAACTCTAAATGCTCTACGTG
  CCCTTACTAGCAAGATACATTAATTCTATTTTACACAGACAACAAACACACTCTAATTTT
  GATTAGGCAAAAGTATTTTATCGAAGTCGATCCCAGCGCCAAATACTGGCATCATCACAA
  ACAGCTATAAGAATGCTGCTATCCCTGCTAAAACTGGTTTGTCGAATAGCAGCACCACAT
  TTATGATGAGTCAGTGTTGTACATTTGGCTTTATGAGGATCTTCTACTTCTAAATCCCAA
  ACATAAAGTTTGCCAACTTGATTGCCCAATGCAAGCATCTTTTGCCAGAAATCCATAGAA
  AACCTCATGTACCAAATGTCACACTGGCTGTAATCAAATCGCCCAAGAATAGTCACATTA
  GATTCACTGGGTTTAATTTTATCTATATCATCTTCCATCTTGCCAGGTTTCCAGCACACA
  ATGGCATTTTCACAAGACTTAGAAAGTATCAAATCGCCTAACCATCGCACACAATCAACA
  TAATTCCTATGTATGTCTCTGGTAGAAAATCAGGAAAAGGATTTTCTGAGAAATAATGGC
  CTGTTAGTTTATTTGGATTATAACAATAGATTCTTAATTGCATTCTCATTCTCTTTGGAT
  TGATCCTNCAAGTTTAAGAGATGAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_152991
• ORF Size: 1203 bp
• Insert Size: 1900
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_152991.1, NP_694536.1
• RefSeq Size: 2413
• RefSeq ORF: 1203
• Locus ID: 8726
• Domains: WD40
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) contains an additional segment within the coding region, which results in immediate translation termination, compared to variant 1. The resulting isoform (b) contains a shorter C-terminus compared to isoform a.