PCDHA4 (NM_031500) Human Untagged Clone

CAT#: SC110571

PCDHA4 (untagged)-Human protocadherin alpha 4 (PCDHA4), transcript variant 2


  "NM_031500" in other vectors (4)

Reconstitution Protocol

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    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PCDHA4
Synonyms CNR1; CNRN1; CRNR1; PCDH-ALPHA4
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_031500, the custom clone sequence may differ by one or more nucleotides


ATGGAGTTTTCCTGGGGAAGCGGCCAGGAATCCCGGCGTCTGCTGCTCTTACTTCTTCTCCTCGCAGCCT
GGGAGGCAGGGAACGGTCAGCTCCACTACTCGGTCTCCGAGGAGGCCAAACACGGCACCTTCGTGGGCCG
CATCGCGCAGGACCTGGGACTGGAGCTGGCGGAGCTGGTGCCGCGCCTGTTCCGGGTGGCGTCCAAGGGC
CGCGGAGGCCTTCTGGAGGTAAATCTGCAGAATGGCATTTTGTTTGTGAATTCTCGGATCGACCGGGAGG
AGCTGTGCCGGCGGAGCGCGGAGTGCAGCATCCACCTGGAGGTGATCGTAGACAGGCCGCTGCAGGTTTT
CCATGTGGACGTGGAGGTGAGGGACATTAACGATAACCCGCCGGTGTTCCCAGCAACACAAAAGAACCTG
TCCATCGCGGAATCCAGGCCGCTTGACTCTCGGTTTCCACTAGAGGGCGCCTCGGATGCAGATATCGGGG
AGAACGCCCTGCTCACTTACAGACTGAGCCCAAATGAATACTTTTCTCTGGAAAAACCACCTGATGACGA
GCTGGTAAAAGGTCTTGGGCTTATATTACGGAAATCTTTAGACAGAGAAGAAGCTCCGGAGATTTTTTTA
GTGCTCACAGCCACTGATGGAGGCAAACCCGAGTTGACTGGCACCGTTCAGTTACTCATCACAGTACTGG
ATGCCAATGACAATGCCCCAGCTTTTGACAGAACCATTTATAAGGTGAGATTACTAGAAAATGTTCCTAA
TGGAACATTGGTAATTAAACTTAACGCCTCAGATTTAGACGAAGGATTGAATGGGGACATTGTTTATTCA
TTCTCAAATGATATTTCGCCAAATGTGAAATCCAAGTTTCACATAGATCCAATTACTGGACAAATTATTG
TAAAGGGATATATTGACTTTGAAGAAAGCAAATCCTATGAAATTATTGTAGAGGGCATTGATAAGGGACA
GCTCCCACTTTCTGGCCATTGTAGAGTTATTGTGGAAGTAGAAGACAACAACGATAATGTCCCAGATTTG
GAATTCAAGTCTTTATCACTTCCAATTAGAGAGGACGCTCCACTGGGTACAGTCATCGCCCTGATCAGCG
TGTCCGACAAAGACATGGGTGTCAATGGGCTGGTCACCTGCTCCTTGACGTCCCACGTCCCCTTCAAGCT
GGTGTCCACCTTCAAGAATTACTACTCGTTGGTGCTGGACAGTGCCCTGGACCGCGAGAGCGTGTCAGCC
TATGAGCTGGTGGTGACCGCGCGAGACGGGGGCTCGCCTTCGCTGTGGGCCACGGCCAGTGTTTCTGTGG
AGGTGGCTGATGTGAACGACAACGCTCCGGCGTTCGCGCAGCCCGAGTACACAGTGTTCGTGAAGGAGAA
CAACCCGCCGGGCTGCCACATCTTCACTGTGTCTGCGTGGGACGCGGACGCGCAGGAGAACGCGCTGGTG
TCCTACTCGCTGGTAGAGCGGCGGGTAGGGGAGCGCGCGCTGTCGAGCTACGTTTCGGTGCATGCGGAGA
GCGGCAAGGTGTACGCGCTGCAGCCGCTGGACCACGAGGAGCTAGAGCTGCTGCAGTTTCAGGTGACCGC
TCGCGATGCCGGCGTGCCACCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAAAACGAC
AACGCGCCAGCACTGCTAGCGCCTCGGGCGGGTGGCACTGGTGGCGCAGTGAGCGAGCTGGTGCCATGGT
CGGTGGGTGTGGGCCACGTGGTGGCAAAGGTGCGCGCGGTGGATGCTGACTCGGGCTACAACGCGTGGCT
TTCGTACGAGCTGCAGCCGGGGACTGGTGGCGCGCGCATCCCGTTCCGCGTGGGGCTGTACACTGGCGAG
ATCAGCACAACGCGTGCCCTGGACGAAACGGACGCTCCGCGCCACCGCCTACTGGTACTGGTGAAGGACC
ACGGCGAGCCCGCGCTGACGGCCACGGCCACTGTGCTGGTGTCACTTGTGGAGAGTGGACAGGCGCCAAA
GGCCTCCTCACGGGCGTTGGTGGGCGCTGTGGGTCCCGATGCTGCGCTGGTGGATGTCAACGTATACCTG
ATCATTGCCATCTGCGCGGTGTCCAGCCTTTTGGTGCTCACGCTGCTGCTGTACACCGCGCTGCGGTGCT
CTGCGCTGCCCACCGAGGGCGCGTGCGCTCCGGGCAAGCCCACGCTGGTGTGCTCCAGTGCGGTGGGGAG
CTGGTCATACTCGCAGCAGAGGAGGCCGAGGGTGTGCTCTGGTGAGGGCCCACCCAAGACCGACCTCATG
GCCTTCAGCCCCAGTTTACCTGACTCTAGGGACAGAGAAGATCAGCTGCAGACAACTGAGGAATCCTTTG
CAAAGGTTAGTGTATAA


>OriGene 5' read for NM_031500 unedited
GTTGTTCAAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGAGACT
GAATATGGAGGATGCAGCTGCACTTGACTGACCGATTAAAAGATTTCCCTTGACTTTGAG
AAACGATATTTAATCAGAACAAAATACTGTGCACTAAAGATGGAGTTTTCCTGGGGAAGC
GGCCAGGAATCCCGGCGTCTGCTGCTCTTACTTCTTCTCCTCGCAGCCTGGGAGGCAGGG
AACGGTCAGCTCCACTACTCGGTCTCCGAGGAGGCCAAACACGGCACCTTCGTGGGCCGC
ATCGCGCAGGACCTGGGACTGGATCTGGCGGAGCTGGTGCCGCGCCTGTTCCGGGTGGCG
TCCAAAAGACACCGGGACCTTCTGGAGGTAAATCTGCAGAATGGCATTTTGTTTGTGAAT
TCTCGGATCGACCGCGAGGAGCTGTGCCGGCGGAGCGCGGAGTGCAGCATCCACCTGGAG
GTGATCGTGGACAGGCCGCTGCAGGTTTTCCATGTGGACGTGGAGGTGAGGGACATTAAC
GATAACCCGCCGGTGTTCCCAGCAACACAAAAGAACCTGTCCATCGCGGAATCCAGGCCG
CTTGACTCTCGGTTTCCACTAGAGGGCGCCTCGGATGCAGATATCGGNGAGAACGCCCTG
CTCACTTACAGACTGAGCCCAAATGAATACTTTTCTCTGGGAAAACCATCTGATGACGAG
CTGGTAAAAGGTCTTGGGCTTATATTACGGAAATCTTTAGACAGAGAAGAAGCTCCGGAG
ATTTTTTTAGTGCTCACAGCCACTGATGGAGGCAAACCCGAGTTGACTGGCCCCGTTCAG
TTACTCATCACAGAACTGGATGCCAATGACAATGCCCCACTTTTGACAGAACATTTTTA
>OriGene 3' read for NM_031500 unedited
CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTTGGTCTCCTCCTTTTT
GCCGAAGGTTATGAAGTCACTTTTGTCAATTTGGCTGTTAGTAGGCTCCTGCCGGATGGA
GATGATTGCAGGAGATCCTGGGATAATGAATTTGTCGGGCAACTCACCGGGACCGGATTG
TTTGGGGTTGCCTGGTCCGTATTTAAAGGTCCAGCTGTTGCTGTTGACACCCGCACCGAC
TGGAGGGGACACTTCTCCTGCCTCTGGTTCTGGTGTTGCACTGGATACTGTTGGCCACTG
CTGATCAGGCCCTCCTGGACCAGCCCGTAGAATGCCAGCCTCCTCTAGGTGCACAGAGCT
GTGCATGCCTGCTCTCAGGGAGGCAGAGTAACGCCAGTCAGGGTTGGGCTGTCGTGGCTT
TGCAAAGGATTCCTCAGTTGTCTGCAGCTGATCTTCTCTGTCCCTAGAGTCAGGTAAACT
GGGGCTGAAGGCCATGAGGTCGGTCTTGGGTGGGCCCTCACCAGAGCACACCCTCGGCCT
CCTCTGCTGCGAGTATGACCAGCTCCCCACCGCACTGGAGCACACCAGCGTGGGCTTGCC
CGGAGCGCACGCGCCCTCGGTGGGCAGCGCAGAGCACCGCAGCGCGGTGTACAGCAGCAG
CGTGAGCACCAAAAGGCTGGACACCGCGCAGATGGCAATGATCAGGTATACGTTGACATC
CACCAGCGCAGCATCGGGACCCACAGCGCCCACCAACGCCCGTGAGGAGGCCTTTGGCGC
CTGTCCACTCTTCACAGTGACACCAGCACAGTGGCCGTGCCCGTCATCGCGGCCTCGCCG
TGGTCCTTCACAGTACCATTAGCCGTGGCGCCGAACGTCCGTTTCGTCCAGGCAGCGTTG
TGCTGATCTCGCAGTGTACACCCCAGCGTACGGGTG
Restriction Sites NotI-NotI     
ACCN NM_031500
ORF Size 2397 bp
Insert Size 2870
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_031500.1, NP_113688.1
RefSeq Size 2498
RefSeq ORF 2397
Locus ID 56144
Domains CA
Protein Families Transmembrane
Gene Summary This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes a shorter isoform (2), compared to isoform 1. This short variant is represented based on data in PMID:10380929.

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