EDAR (NM_022336) Human Untagged Clone

CAT#: SC112525

EDAR (untagged)-Human ectodysplasin A receptor (EDAR)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EDAR
• Synonyms: DL; ECTD10A; ECTD10B; ED1R; ED3; ED5; EDA-A1R; EDA1R; EDA3; HRM1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112525 sequence for NM_022336 edited (data generated by NextGen Sequencing)
  ATGGCCCATGTGGGGGACTGCACGCAGACGCCCTGGCTCCCCGTCCTGGTGGTGTCTCTG
  ATGTGCTCAGCCCGAGCGGAATACTCAAACTGCGGTGAGAACGAGCACTACAACCAGACT
  ACGGGGCTGTGCCAGGAGTGCCCCCCGTGTGGGCCGGGAGAGGAGCCCTACCTGTCCTGT
  GGCTACGGCACCAAAGACGAGGACTACGGCTGCGTCCCCTGCCCGGCGGAGAAGTTTTCC
  AAAGGAGGCTACCAGATATGCAGGCGTCACAAAGACTGTGAGGGCTTCTTCCGGGCCACC
  GTGCTGACACCAGGGGACATGGAGAATGACGCTGAGTGTGGCCCTTGCCTCCCTGGCTAC
  TACATGCTGGAGAACAGACCGAGGAACATCTATGGCATGGTCTGCTACTCCTGCCTCCTG
  GCACCCCCCAACACCAAGGAATGTGTGGGAGCCACTTCAGGAGCTTCTGCCAACTTCCCT
  GGCACCTCGGGCAGCAGCACCCTGTCTCCCTTCCAGCACGCCCACAAAGAACTCTCAGGC
  CAAGGACACCTGGCCACTGCCCTGATCATTGCAATGTCCACCATCTTCATCATGGCCATC
  GCCATCGTCCTCATCATCATGTTCTACATCCTGAAGACAAAGCCCTCTGCCCCAGCCTGT
  TGCACCAGCCACCCGGGGAAGAGCGTGGAGGCCCAAGTGAGCAAGGACGAGGAGAAGAAA
  GAGGCCCCAGACAACGTGGTGATGTTCTCTGAGAAGGATGAATTTGAGAAGCTGACAGCA
  ACTCCAGCAAAGCCCACCAAGAGCGAGAACGATGCCTCATCCGAGAATGAGCAGCTGCTG
  AGCCGGAGCGTCGACAGTGATGAGGAGCCCGCCCCTGACAAGCAGGGCTCCCCGGAGCTG
  TGCCTGCTGTCGCTGGTTCACCTGGCCAGGGAGAAGTCTGCCACCAGCAACAAGTCAGCC
  GGGATTCAAAGCCGGAGGAAAAAGATCCTCGATGTGTATGCCAACGTGTGTGGAGTCGTG
  GAAGGTCTTAGCCCCACGGAGCTGCCATTTGATTGTCTCGAGAAGACTAGCCGAATGCTC
  AGCTCCACGTACAACTCTGAGAAGGCTGTTGTGAAAACGTGGCGCCACCTCGCCGAGAGC
  TTCGGCCTGAAGAGGGATGAGATTGGGGGCATGACAGACGGCATGCAACTCTTTGACCGC
  ATCAGCACGGCAGGCTACAGCATCCCTGAGCTACTCACAAAACTGGTGCAGATTGAGCGG
  CTGGATGCTGTGGAGTCCTTGTGTGCAGACATACTGGAGTGGGCGGGGGTTGTGCCACCT
  GCCTCCCAGCCACATGCTGCATCCTGA
  
  Clone variation with respect to NM_022336.3
  106 t=>c;750 c=>t;1056 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022336 unedited
  CAAATTTGTATACGACTACTATAGGCGGCCGACGATTCGGCACGAGCCCGGGAAGCCCTT
  TAAACGGAAAGGAAGCGGGGCTAGTGTCAGAGAGGTGTGCCAGGTCCCAGGCAGCCCTGC
  TGGCCCCTAAGGACATAGAGTACCTGCTTCTGAGAGGGCTGCCACGGTGGCCACCTGTGA
  AGCCTGTCACCCAGAACTGGATGGTACCTGACTTTCTTCATAGACCCATCTTCTGCTGGG
  ACTGAAGCTGACCTCCAACAGAAGCCAGGTGAGCCCTTGGGAGAGGATGGCCCATGTGGG
  GGACTGCACGCAGACGCCCTGGCTCCCCGTCCTGGTGGTGTCTCTGATGTGCTCAGCCCG
  AGCGGAATACTCAAACTGCGGTGAGAACGAGCACTACAACCAGACTACGGGGCTGTGCCA
  GGAGTGCCCCCCGTGTGGGCCGGGAGAGGAGCCCTACCTGTCCTGTGGCTACGGCACCAA
  AGACGAGGACTACGGCTGCGTCCCCTGCCCGGCGGAGAAGTTTTCCAAAGGAGGCTACCA
  GATATGCAGGCGTCACAAAGACTGTGAGGGCTTCTTCCGGGCCACCGTGCTGACACCAGG
  GGACATGGAGAATGACGCTGAGTGTGGCCCTTGCCTCCCTGGCTACTACATGCTGGAGAA
  CAGACCGAGGAACATCTATGGCATGGTCTGCTACTCCTGCCTCCTGGCACCCCCCAACAC
  CAAGGAATGTGTGGGAGCCACTTCAGGAGCTTCTGCCAACTTCCCTGGCACCTCGGGCAG
  CAGCACCCTGTCTCCCTTCCAGCACGCCCACAAAGAACTCTCAGGCCAAGGACACCTGGG
  CCACTGCCCCTGATCATTGCATGTCCACCATCTTCATCATGGCCATCGNCATCGNCCTCA
  TCATCATGTTCTACATCCTGAAGACAAAGCCTCTGCCCAGCCTGTTGCACAGNCCCCCGN
  GNAGAGCGTGGAGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_022336 unedited
  CCCCCACCTATTAGTTTGNACCGTCGGCCGCATNCTACGATGCGGTTTTTTTTTTTTTTT
  TTTTTAAATCTTATTAATATGTTTATTGACGATATAAAATATAATAAGTTATATATATAC
  AGAATTAGACAAAAATAATATTGACAAGACTTCACTGTCTAAGGGCCACAGACCTACCCT
  GGGGTGTTTTCTAAATGTTTTAAAGTATTGCAGAATTATGAATATCTCCACACAAAAATG
  GCAGGATGGAGTCCCAGCTTTGGTCAGTGAGAATTATTATGATCTCATTGTTCTGAATCC
  CATAACATAGGCTAAAGCTTGTCAGAGTAAATCCCATGTTTCCAAATAAGTAAATGACAA
  GGGAATTTGTAACTATATAAGGAATAGCTCCCTAAAAATGGCAGGTGGAGAGCCAATGGA
  ACATGAGCTGACACTGGCTGGCCTTACAGCCCCAGAATTCTAATAGTGTGAAATGAGGCC
  AAAGCACCAGGAGCAGAGAACAGCCACCCCACTCTTTCGCTGAAAACATTCTGAGGAGGG
  TGCAAGCTGTTATCCTGGAATGGCACACTCATCACAAGTGACAGTTTGCAGTCTAATTAA
  GGGGAGACTCACTCATCATCATCACAAGGCAGGGGGAAAAGGGGGCACCACAGGATTTCA
  AAGAGGAAATAAAAGGATAATTAAGCTCTGCCTGTGGAGTATTTACCTGGCAGGGTAAAC
  CAAATAGGTTTTGAAAACAGCAGCAAACAGACACAGTAAATGATGATATTAAATATTCAG
  GACCTCATTATGATCCTCTCACAGTATGACTACATTTCNTGGNGGGAAATGCTTTTTTTG
  GGTTTAAAGAAAAACCTGATTTTTCCCTTAAGATTTTTTTCATCATGCACTTGTAATTTT
  TACACCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_022336
• ORF Size: 1347 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_022336.1, NP_071731.1
• RefSeq Size: 4235
• RefSeq ORF: 1347
• Locus ID: 10913
• Domains: DEATH
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction
• Gene Summary: This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]