ERAP2 (NM_022350) Human Untagged Clone

CAT#: SC112532

ERAP2 (untagged)-Human endoplasmic reticulum aminopeptidase 2 (ERAP2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ERAP2
• Synonyms: L-RAP; LRAP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_022350, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTCCATTCTTCTGCAATGGTTAATTCACACAGAAAACCAATGTTTAACATTCACAGAGGATTTTACT
  GCTTAACAGCCATCTTGCCCCAAATATGCATTTGTTCTCAGTTCTCAGTGCCATCTAGTTATCACTTCAC
  TGAGGATCCTGGGGCTTTCCCAGTAGCCACTAATGGGGAACGATTTCCTTGGCAGGAGCTAAGGCTCCCC
  AGTGTGGTCATTCCTCTCCATTATGACCTCTTTGTCCACCCCAATCTCACCTCTCTGGACTTTGTTGCAT
  CTGAGAAGATCGAAGTCTTGGTCAGCAATGCTACCCAGTTTATCATCTTGCACAGCAAAGATCTTGAAAT
  CACGAATGCCACCCTTCAGTCAGAGGAAGATTCAAGATACATGAAACCAGGAAAAGAACTGAAAGTTTTG
  AGTTACCCTGCTCATGAACAAATTGCACTGCTGGTTCCAGAGAAACTTACGCCTCACCTGAAATACTATG
  TGGCTATGGACTTCCAAGCCAAGTTAGGTGATGGCTTTGAAGGGTTTTATAAAAGCACATACAGAACTCT
  TGGTGGTGAAACAAGAATTCTTGCAGTAACAGATTTTGAGCCAACCCAGGCACGCATGGCTTTCCCTTGC
  TTTGATGAACCGTTGTTCAAAGCCAACTTTTCAATCAAGATACGAAGAGAGAGCAGGCATATTGCACTAT
  CCAACATGCCAAAGGTTAAGACAATTGAACTTGAAGGAGGTCTTTTGGAAGATCACTTTGAAACTACTGT
  AAAAATGAGTACATACCTTGTAGCCTACATAGTTTGTGATTTCCACTCTCTGAGTGGCTTCACTTCATCA
  GGGGTCAAGGTGTCCATCTATGCATCCCCAGACAAACGGAATCAAACACATTATGCTTTGCAGGCATCAC
  TGAAGCTACTTGATTTTTATGAAAAGTACTTTGATATCTACTATCCACTCTCCAAACTGGATTTAATTGC
  TATTCCTGACTTTGCACCTGGAGCCATGGAAAATTGGGGCCTCATTACATATAGGGAGACGTCACTGCTT
  TTTGACCCCAAGACCTCTTCTGCTTCCGATAAACTGTGGGTCACCAGAGTCATAGCCCATGAACTGGCGC
  ACCAGTGGTTTGGCAACCTGGTCACAATGGAATGGTGGAATGATATTTGGCTTAAGGAGGGTTTTGCAAA
  ATACATGGAACTTATCGCTGTTAATGCTACATATCCAGAGCTGCAATTTGATGACTATTTTTTGAATGTG
  TGTTTTGAAGTAATTACAAAAGATTCATTGAATTCATCCCGCCCTATCTCCAAACCAGCGGAAACCCCGA
  CTCAAATACAGGAAATGTTTGATGAAGTTTCCTATAACAAGGGAGCTTGTATTTTGAATATGCTCAAGGA
  TTTTCTGGGTGAGGAGAAATTCCAGAAAGGAATAATTCAGTACTTAAAGAAGTTCAGCTATAGAAATGCT
  AAGAATGATGACTTGTGGAGCAGTCTGTCAAATAGTTGTTTAGAAAGTGATTTTACATCTGGTGGAGTTT
  GTCATTCGGATCCCAAGATGACAAGTAACATGCTCGCCTTTCTGGGGGAAAATGCAGAGGTCAAAGAGAT
  GATGACTACATGGACTCTCCAGAAAGGAATCCCCCTGCTGGTGGTTAAACAAGACGGGTGTTCACTCCGA
  CTGCAACAGGAGCGCTTCCTCCAGGGGGTTTTCCAGGAAGACCCTGAATGGAGGGCCCTGCAGGAGAGGT
  ACCTGTGGCATATCCCATTGACCTACTCCACGAGTTCTTCTAATGTGATCCACAGACACATTCTAAAATC
  AAAGACAGATACTCTGGATCTACCTGAAAAGACCAGTTGGGTGAAATTTAATGTGGACTCAAATGGTTAC
  TACATCGTTCACTATGAGGGTCATGGATGGGACCAACTCATTACACAGCTGAATCAGAACCACACACTTC
  TCAGACCTAAGGACAGAGTAGGTCTGATTCATGATGTGTTTCAGCTAGTTGGTGCAGGGAGACTGACCCT
  AGACAAAGCTCTTGACATGACTTACTACCTCCAACATGAAACAAGCAGCCCCGCACTTCTCGAAGGTCTG
  AGTTACTTGGAATCGTTTTACCACATGATGGACAGAAGGAATATTTCAGATATCTCTGAAAACCTCAAGC
  GTTACCTTCTTCAGTATTTTAAGCCAGTGATTGACAGGCAAAGCTGGAGTGACAAGGGCTCAGTCTGGGA
  CAGGATGCTCCGCTCGGCTCTCTTGAAGCTGGCCTGTGACCTGAACCATGCTCCTTGCATCCAGAAAGCT
  GCTGAACTCTTCTCCCAGTGGATGGAATCCAGTGGAAAATTAAATATACCAACAGATGTTTTAAAGATTG
  TGTATTCTGTGGGTGCTCAGACAACAGCAGGATGGAATTACCTTTTAGAGCAATATGAACTGTCAATGTC
  AAGTGCTGAACAAAACAAAATTCTGTATGCTTTGTCAACGAGCAAGCATCAGGAAAAGTTACTGAAGTTA
  ATTGAACTAGGAATGGAAGGAAAGGTTATCAAGACACAGAACTTGGCAGCTCTCCTTCATGCGATTGCCA
  GACGTCCAAAGGGGCAGCAACTAGCATGGGATTTTGTAAGAGAAAATTGGACCCATCTTCTGAAAAAATT
  TGACTTGGGCTCATATGACATAAGGATGATCATCTCTGGCACAACAGCTCACTTTTCTTCCAAGGATAAG
  TTGCAAGAGGTGAAACTATTTTTTGAATCTCTTGAGGCTCAAGGATCACATCTGGATATTTTTCAAACTG
  TTCTGGAAACGATAACCAAAAATATAAAATGGCTGGAGAAGAATCTTCCGACTCTGAGGACTTGGCTAAT
  GGTTAATACTTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022350 unedited
  CTGTCAGGATTTTGTAACACGACTCACTATGGNNGGCGGCCGCGCAATTCGGCACGAGGG
  TCAAATCTGCAGCAGCATGATTTAAGATTAAATTCATGTATTGAAAATATTGTTCAGACC
  CCATGTGACATAACTGGAGCCAGTGCAGTGCCATGAAGAACTACGAGATTAGCCTGGATA
  TTAACTTGTCTTCTAGAGAATAGATTTCATGTTCCATTCTTCTGCAATGGTTAATTCACA
  CAGAAAACCAATGTTTAACATTCACAGAGGATTTTACTGCTTAACAGCCATCTTGCCCCA
  AATATGCATTTGTTCTCAGTTCTCAGTGCCATCTAGTTATCACTTCACTGAGGATCCTGG
  GGCTTTCCCAGTAGCCACTAATGGGGAACGATTTCCTTGGCAGGAGCTAAGGCTCCCCAG
  TGTGGTCATTCCTCTCCATTATGACCTCTTTGTCCACCCCAATCTCACCTCTCTGGACTT
  TGTTGCATCTGAGAAGAGCGAAGTCTTGGTCAGCAATGCTACCCAGTTTATCATCTTGCA
  CAGCAAAGATCTTGAAATCACGAATGCCACCCTTCAGTCAGAGGAAGATTCAAGATACAT
  GAAACCAGGAAAAGAACTGAAAGTTTTGAGTTACCCTGCTCATGAACAAATTGCACTGCT
  GGTTCCAGAGAAACTTACGCCTCACCTGAGATACTATGTGGCTATGGACTTCCAAGCCAA
  GTTAGGTGATGGCTATGAAGGGTTNTATAAAAGCACATACAGAACTCTTGGTGGTGAAAC
  AAGAAGTCTTGCAGTAACAGATTTTGAGCCAACCCAGNCACGCATGGCTATCCCTTGCTT
  TGATGAACGTGTGTTCAAGCCTACTTTTCATCAAGAACTAAGAGAGAGCAGGCATATGCA
  CTATCCACATGCCTAAGGTCAGACGATGAAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_022350 unedited
  CGCAATCTAGAATCGAGTTTTTTTTTTTTTTTTTTCTTTTTCTTTTTTTTTTTTTTTTTT
  TTTTTTTTTGAAACAAAGTCTCGCTCAGTCACCCAAGCTGGAATGCAGTGGGGCAATCTC
  GGCTCACTGGAAGCTCCACCTCCCGGGTTTATGCCATTTTCCTGCTGCAGCCTGCCGAGT
  AGCTGGGACTACAGGCACCTGCCACCATGCCCGGGTAATTTTTTGTATTTCTAACGGAGA
  CGGGGTCTCACCGTGTTAACCAAGAAGGGCTCCATCTCCTGACCTCGGGATCCGCCCTTC
  TCAACCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTACTTTTTCT
  ATTGACCATTTAAGTATTAACCATTAGCCAAGTCCTCAAAGTCGGAAGATTCTTCTCCAG
  CCATTTTATATTTTTGGGTATCGTTTCCAGAACAGTTTGAAAAATATCCAGATGTGATCC
  TTGAGCCTCAAGAGATTCAAAAAATAGTTTCACCTCTTGCAACTTATCCTTGGAAGAAAA
  GTGAGCTGTTGTGCCAGAGATGATCATCCTTATGTCATATGAGCCCAAGTCAAATTTTTT
  CAGAAGATGGGTCCAATTTTCTCTTAAAAATCCCATGCTAGTTGCTGCCCCCTTGGACGT
  CTGGCCATCGCATGAAAGAGAGCTGCCAAGCTCTGTGCCTTGAAACCCTTCCCTCCATCC
  CTAGTCATTAACTTCATAACCTTTCCCTGAGCTAGCTCGTTGAAAAGATACAGAATTTGT
  TTTGTCACCACTGAACATGACAGTCAATAGCTCTAAAAGGNATTCCTCCTGCTGTGTCTG
  AGCCCCAAGATAACAATCTTAAAAATCCGTGGTATATAAATTTCCCTGATCCATCCCTGG
  AAAAAGTTCACACTTCTGGATGCAGAGCATGTTCAGTCACAGCACCTTAGAACCGACGGA
  ATCTGTCCAATGAACCTGGACTCACCTTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_022350
• ORF Size: 2883 bp
• Insert Size: 3510
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_022350.1, NP_071745.1
• RefSeq Size: 3356
• RefSeq ORF: 2883
• Locus ID: 64167
• Domains: Peptidase_M1
• Protein Families: Druggable Genome, Protease
• Gene Summary: This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. [provided by RefSeq, Jul 2016]
  Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1 and 2 both encode the same protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.