NAB2 (NM_005967) Human Untagged Clone

CAT#: SC112690

NAB2 (untagged)-Human NGFI-A binding protein 2 (EGR1 binding protein 2) (NAB2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NAB2
• Synonyms: MADER
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112690 sequence for NM_005967 edited (data generated by NextGen Sequencing)
  ATGCACAGAGCGCCTTCCCCCACAGCCGAGCAGCCGCCGGGCGGAGGGGACAGCGCCCGC
  CGGACCCTGCAGCCCAGACTCAAGCCCAGTGCCCGAGCCATGGCACTGCCTCGGACGCTG
  GGGGAGCTGCAGCTGTACCGGGTCCTGCAGCGCGCCAACCTCCTTTCCTACTATGAGACC
  TTCATCCAGCAGGGAGGGGACGACGTGCAGCAGCTGTGTGAGGCGGGTGAGGAGGAGTTT
  CTGGAGATCATGGCACTTGTGGGCATGGCCACCAAGCCCCTCCATGTCCGGCGCCTGCAG
  AAGGCACTGAGAGAGTGGGCCACCAATCCAGGGCTCTTCAGTCAACCAGTGCCTGCTGTT
  CCCGTCTCCAGCATCCCGCTCTTCAAGATCTCTGAGACTGCGGGTACCCGGAAAGGGAGC
  ATGAGCAATGGGCATGGCAGCCCAGGGGAAAAGGCAGGCAGTGCCCGCAGTTTTAGCCCC
  AAGAGCCCCCTTGAACTTGGAGAGAAGCTATCACCACTGCCTGGGGGACCTGGGGCAGGG
  GACCCCCGGATCTGGCCAGGCCGGAGCACTCCAGAGTCGGACGTTGGGGCAGGAGGAGAA
  GAGGAGGCTGGCTCGCCCCCCTTCTCCCCCCCTGCAGGGGGAGGAGTCCCTGAGGGGACT
  GGGGCTGGGGGGCTGGCAGCAGGTGGGACTGGGGGTGGTCCAGACCGACTGGAGCCAGAG
  ATGGTACGCATGGTGGTGGAAAGTGTGGAGAGGATCTTCCGGAGCTTCCCAAGGGGGGAT
  GCTGGGGAGGTCACATCCCTGCTAAAGCTGAATAAGAAGCTGGCACGGAGCGTTGGGCAC
  ATCTTTGAGATGGATGATAATGACAGCCAGAAGGAAGAGGAGATCCGCAAATACAGCATC
  ATCTATGGCCGTTTCGACTCTAAGCGGCGGGAGGGCAAGCAGCTCAGCCTGCACGAGCTC
  ACCATCAACGAGGCTGCTGCCCAGTTCTGCATGAGGGACAACACACTCTTATTACGGAGA
  GTGGAGCTCTTCTCTTTGTCCCGCCAAGTAGCCCGAGAGAGCACCTACTTGTCCTCCTTG
  AAGGGCTCCAGGCTTCACCCTGAAGAACTGGGAGGCCCTCCACTGAAGAAGCTGAAACAA
  GAGGTTGGAGAACAGAGTCACCCTGAAATCCAGCAGCCTCCCCCAGGCCCTGAGTCCTAT
  GTACCCCCATACCGCCCCAGCCTGGAGGAGGACAGCGCCAGCCTGTCTGGGGAGAGTCTG
  GATGGACATTTGCAGGCTGTGGGGTCATGTCCAAGGCTGACGCCGCCCCCTGCTGACCTG
  CCTCTGGCATTGCCAGCCCATGGGCTATGGAGCCGACACATCCTGCAGCAGACACTGATG
  GACGAGGGGCTGCGGCTCGCCCGCCTCGTCTCCCACGACCGCGTGGGCCGCCTCAGCCCC
  TGTGTGCCTGCGAAGCCACCTCTCGCAGAGTTCGAGGAAGGGCTGCTGGACAGATGTCCT
  GCCCCAGGACCCCATCCCGCGCTGGTGGAGGGTCGCAGGAGCAGCGTGAAAGTGGAGGCT
  GAGGCCAGCCGGCAGTGA
  
  Clone variation with respect to NM_005967.3
  1005 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005967 unedited
  GTAATACGACTCACTATAGGGCGGCCGCCGATTCGGCACGAGGCAGACAGAGGCGCGGAG
  GCTCGGAGAGAGAAGACGTGGAGGGAGGGACAGAGCCTGGACAGCGGTGGACACGGCATC
  GTGCGCGGGGAAGAGGGCAGCACGCAGCAGGCGCCGAGCGCCGGGCACCGAGAAGGGCAG
  CCCGGGTGATCTCCGGCCGTCCATGCACAGAGCGCCTTCCCCCACAGCCGAGCAGCCGCC
  GGGCGGAGGGGACAGCGCCCGCCGGACCCTGCAGCCCAGACTCAAGCCCAGTGCCCGAGC
  CATGGCACTGCCTCGGACGCTGGGGGAGCTGCAGCTGTACCGGGTCCTGCAGCGCGCCAA
  CCTCCTTTCCTACTATGAGACCTTCATCCAGCAGGGAGGGGACGACGTGCAGCAGCTGTG
  TGAGGCGGGTGAGGAGGAGTTTCTGGAGATCATGGCACTTGTGGGCATGGCCACCAAGCC
  CCTCCATGTCCGGCGCCTGCAGAAGGCACTGAGAGAGTGGGCCACCAATCCAGGGCTCTT
  CAGTCAACCAGTGCCTGCTGTTCCCGTCTCCAGCATCCCGCTCTTCAAGATCTCTGAGAC
  TGCGGGTACCCGGAAAGGGAGCATGAGCAATGGGCATGGCAGCCCAGGGGAAAAGGCAGG
  CAGTGCCCGCAGTTTTAGCCCCAAGAGCCTCCTGGAACTTGGAGAGAAGCTATCACCCCT
  GCCTGGGGGACCTGGGGCAGGGGACCCCCCGATCTGGCCAGGCCCGAACACCTCCANAAT
  CCGAACGTTGGCGCATGAGGAATAAAAGGAGGCTGGGCTTGCCCCCCTTCCTCCCCCCTG
  GAGGGGGAGGAGTCCCTGAAGGGACCGGGGCTGCGGGCCTGCACCAGGTGGCACTGGGGC
  GGGTCAAACCGCATTCGCCAAAACGGACACATGTGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005967 unedited
  CCCCCGCTACTAGNATCGAGTTTTTTTTTTTTTTTTTTCCTAAGCCATAAAATAAATTTT
  ATTCCAAAATAACAAAATAAATAATCTACTGTACACAATCTGAAAAGAAAGACGCTCTAA
  CTGCTCAAATAGGTGCTGCGGTCCAGCCCCCAGCTGGAGGAGACCCTGAGTCCAACCCAG
  GCCTCCCGAGGGGGCCAGTGAAGGGATCCCACACCCACCGCCCCTATGTAGGGCAGGGAA
  GAAATTGCAAAGGACTTGGGGGATAGATGGGAATGGGAGGGCAAACTGCAGCACTTGTTA
  AATTAATTAAAGAAACAAACCAGAAGCACAAAAACGGGGAAGGAGAGGGGAGAAGGAGCA
  GGTCCAGTGTTCCCAGGCCCCCAATTCTGGGGGCAAATGTTGCCACTTTTAGCTGGACCT
  TCCCAGGGAAGTCCCCCTTTCCCCCTTGTCCAAACTGAGTCCAACTGCTCACACCACTGG
  TGCAAACCTAAAGAGAATGGGAGTGTGTTGTGTGAGGGAGGGGAAAACCCCAGATGCCCT
  GGAGGCAGAGTCCTTGCCCCCTCGCTCTGGGCAGGGGTGAGGGCACCACGCACCCTCCTT
  GTGTCCTCTCTCCAGGCCTTTGCTTGTTATTTGCTTGAAGCCCCACAGTCTTATGCCCAT
  GGAGCAGGCTGGGAGGCACGAGAAGGGCACACGAAGGATCCAGGGTTGTGACCACATCTC
  CGGCGATGGAAAGCGTGGCGCGTCTGCGCGACCCACAAGTCTGACTCCCTGGGTCTGAAA
  ACCCATTGCAACCCTAACTGCCGGCTGGGCTCAGCCCCCATTTGACGCTTGTCCTTGGGA
  CCCTCCCCATCGCGGAATGGGGATCTTGGGCCGGACCATTTGTTCAGCACCCTTTCTTNT
  CACTTTGCCAGAGGTGGCCTTTAGCCCCCCGTGCTGAGCGGACCCGCGTTCTGGGAAACA
  GGCGGACATCCACCCCCCCCTCCCGTCTGCGAG
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_005967
• Insert Size: 2540 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005967.2, NP_005958.1
• RefSeq Size: 2512 bp
• RefSeq ORF: 1578 bp
• Locus ID: 4665
• Cytogenetics: 12q13.3
• Domains: NCD1, NCD2
• Protein Families: Transcription Factors
• Gene Summary: 'This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).