Azurocidin (AZU1) (NM_001700) Human Untagged Clone

CAT#: SC112711

AZU1 (untagged)-Human azurocidin 1 (AZU1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AZU1
• Synonyms: AZAMP; AZU; CAP37; HBP; hHBP; HUMAZUR; NAZC
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112711 sequence for NM_001700 edited (data generated by NextGen Sequencing)
  ATGACCCGGCTGACAGTCCTGGCCCTGCTGGCTGGTCTGCTGGCGTCCTCGAGGGCCGGC
  TCCAGCCCCCTTTTGGACATCGTTGGCGGCCGGAAGGCGAGGCCCCGCCAGTTCCCGTTC
  CTGGCCTCCATTCAGAATCAAGGCAGGCACTTCTGCGGGGGTGCCCTGATCCATGCCCGC
  TTCGTGATGACCGCGGCCAGCTGCTTCCAAAGCCAGAACCCTGGGGTTAGCACCGTGGTG
  CTGGGTGCCTATGACCTGAGGCGGCGGGAGAGGCAGTCCCGCCAGACGTTTTCCATCAGC
  AGCATGAGCGAGAATGGCTACGACCCCCAGCAGAACCTGAACGACCTGATGCTGCTTCAG
  CTGGACCGTGAGGCCAACCTCACCAGCAGCGTGACGATACTGCCACTGCCTCTGCAGAAC
  GCCACGGTGGAAGCCGGCACCAGATGCCAGGTGGCCGGCTGGGGGAGCCAGCGCAGTGGG
  GGGCGTCTCTCCCGTTTTCCCAGGTTCGTCAACGTGACTGTGACCCCCGAGGACCAGTGT
  CGCCCCAACAACGTGTGCACCGGTGTGCTCACCCGCCGCGGTGGCATCTGCAATGGGGAC
  GGGGGCACCCCCCTCGTCTGCGAGGGCCTGGCCCACGGCGTGGCCTCCTTTTCCCTGGGG
  CCCTGTGGCCGAGGCCCTGACTTCTTCACCCGAGTGGCGCTCTTCCGAGACTGGATCGAT
  GGTGTTCTCAACAACCCGGGACCGGGGCCAGCCTAG
  
  Clone variation with respect to NM_001700.3
  222 c=>t;507 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001700 unedited
  TCATATTTGTATACTATACTATAGGCGGCACGCGATTCGGCACGAGCCGCCATGACCCGG
  CTGACAGTCCTGGCCCTGCTGGCTGGTCTGCTGGCGTCCTCGAGGGCCGGCTCCAGCCCC
  CTTTTGGACATCGTTGGCGGCCGGAAGGCGAGGCCCCGCCAGTTCCCGTTCCTGGCCTCC
  ATTCATAATCAAGGCAGGCACTTCTGCGGGGGTGCCCTGATCCATGCCCGCTTCGTGATG
  ACCGCGGCCAGCTGCTTCCAAAGCCAGAACCCTGGGGTTAGCACCGTGGTGCTGGGTGCC
  TATGACCTGAGGCGGCGGGAGATGCAGTCCCGCCAGACGTTTTCCATCAGCAGCATGAGC
  GAGAATGGCTACGACCCCCATCAGAACCTGAACGACCTGATGCTGCTTCAGCTGGACCGT
  GAGGCCAACCTCACCAGCAGCGTGACGATACTGCCACTGCCTCTGCAGAACGCCACGGTG
  GAAGCCGGCACCATATGCCATGTGGCCGGCTGGGGGATCCAGCGCAGTGGGGGGCGTCTC
  TCCCGTTTTCCCAGGTTCGTCAACGTGACTGTGACCCCCGATGACCAGTGTCGCCCCAAC
  AACGTGTGCACCGGTGTGCTCACCCGCCGCGGTGGCANTCTGCATGGGGACGGAGGCACC
  CCCCTCGTCTGCGATGGCCTGGCCCACAGCGTGCCCTNCTTTTCCCTGGGGCCCTGTGGC
  CGATGCCCTGACTTCTTCACCCGAGTGGCGCTCTTNCGAGACTGGATCGATGGGTGTCTC
  AACATCCCGGNACCCGGGCCAGCCTATGGGGGCCTGTGACCTCCATGGGAGCCCAGTCCC
  GCCTTCACACTNCGGNGCTTCGNACCCACTCCCAGGNCCCGCCCTGNCCCGCTCAGNCAA
  ATGGGCCTGNCTGTATAANAACCCGACCTCCCTGAAAAAAAAAAAAAAAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001700
• Insert Size: 1000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001700.3, NP_001691.1
• RefSeq Size: 912 bp
• RefSeq ORF: 756 bp
• Locus ID: 566
• Cytogenetics: 19p13.3
• Domains: Tryp_SPc
• Protein Families: Druggable Genome, Protease
• Gene Summary: 'Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Nov 2015]'