MAPRE1 (NM_012325) Human Untagged Clone

CAT#: SC115455

MAPRE1 (untagged)-Human microtubule-associated protein, RP/EB family, member 1 (MAPRE1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MAPRE1
• Synonyms: EB1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115455 sequence for NM_012325 edited (data generated by NextGen Sequencing)
  ATGGCAGTGAACGTATACTCAACGTCAGTGACCAGTGATAACCTAAGTCGACATGACATG
  CTGGCCTGGATCAATGAGTCTCTGCAGTTGAATCTGACAAAGATCGAACAGTTGTGCTCA
  GGGGCTGCGTATTGTCAGTTTATGGACATGCTGTTCCCTGGCTCCATTGCCTTGAAGAAA
  GTGAAATTCCAAGCTAAGCTAGAACACGAGTACATCCAGAACTTCAAAATACTACAAGCA
  GGTTTTAAGAGAATGGGTGTTGACAAAATAATTCCTGTGGACAAATTAGTAAAAGGAAAG
  TTTCAGGACAATTTTGAATTCGTTCAGTGGTTCAAGAAGTTTTTCGATGCAAACTATGAT
  GGAAAAGACTATGACCCTGTGGCTGCCAGACAAGGTCAAGAAACTGCAGTGGCTCCTTCC
  CTTGTTGCTCCAGCTCTGAATAAACCGAAGAAACCTCTCACTTCTAGCAGTGCAGCTCCC
  CAGAGGCCCATCTCAACACAGAGAACCGCTGCGGCTCCTAAGGCTGGCCCTGGTGTGGTG
  CGAAAGAACCCTGGTGTGGGCAACGGAGACGACGAGGCAGCTGAGTTGATGCAGCAGGTC
  AACGTATTGAAACTTACTGTTGAAGACTTGGAGAAAGAGAGGGATTTCTACTTCGGAAAG
  CTACGGAACATTGAATTGATTTGCCAGGAGAACGAGGGGGAAAACGACCCTGTATTGCAG
  AGGATTGTAGACATTCTGTATGCCACAGATGAAGGCTTTGTGATACCTGATGAAGGGGGC
  CCACAGGAGGAGCAAGAAGAGTATTAA
  
  Clone variation with respect to NM_012325.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012325 unedited
  CGCCGTTCGGATTTTGTATACGACTCATATAGGCGGCCGCGCAATTCGCACGAGGCCGAG
  CTCCGCCCCCGGCGCGCGGCTGAGTCCCTCTCTATAAAAGGAGCCGGCGGAGGATGACGA
  GCCTTTACGTCGGCGCGTAACGAGGGGAAGATGGCAGTGAACGTATACTCAACGTCAGTG
  ACCAGTGATAACCTAAGTCGACATGACATGCTGGCCTGGATCAATGAGTCTCTGCAGTTG
  AATCTGACAAAGATCGAACAGTTGTGCTCAGGGGCTGCGTATTGTCAGTTTATGGACATG
  CTGTTCCCTGGCTCCATTGCCTTGAAGAAAGTGAAATTCCAAGCTAAGCTAGAACACGAG
  TACATCCAGAACTTCAAAATACTACAAGCAGGTTTTAAGAGAATGGGTGTTGACAAAATA
  ATTCCTGTGGACAAATTAGTAAAAGGAAAGTTTCAGGACAATTTTGAATTCGTTCAGTGG
  TTCAAGAAGTTTTTCGATGCAAACTATGATGGAAAAGACTATGACCCTGTGGCTGCCAGA
  CAAGGTCAAGAAACTGCAGTGGCTCCTTCCCTTGTTGCTCCAGCTCTGAATAAACCGAAG
  AAACCTCTCACTTCTAGCAGTGCAGCTCCCCAGAGGCCCATCTCAACACAGAGAACCGCT
  GCGGCTCCTAAGGCTGGCCCTGGTGTGGTGCGAAAGAACCCTGGTGTGGGCAACGGAGAC
  GACGAGGCAGCTGAGTTGATGCAGCAGGTCAACGTATTGAAACCTACTGTTGAAGACTTG
  GAGAAAGAGAGGGATTTCTACTTCGGGAAGCTACGGGACATTGAATTGATTTGCCACGAG
  ACGCAGGGGAAAACGACCCTGTATTGCAGAAGATTGTANACATCTGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012325 unedited
  CGCGGCCGCAATCTAGAATCGAGTTTTTTTTTTTTTTTTTTTTTACTCTTGAAAACAGAA
  TTTTATTTAGAAACTGTTTAAAGTAGAAAAAAACCCTGTCAAGAAAGACCAGGTGGAAAA
  TGGGTTCCCAATAAAATGGAATTTTAGGGCAACAAAAGTCTAAAAGGCCACAAAAGAGAA
  ATAGCACCACTGTCATTTGAACAATGGCTAGTTACTTGCATTTTTTGGCATTGTTAATCA
  CTGAATCTGGGTTTTCCTCTGAATTCCACACAGAGCATGCACTACACAACATTTTTATCA
  TAAAATACTTGCTTTCTACACACATTTCAGGACAAGCTACCACCAGAAACAAATCAATAC
  AAATACATCAGGGGCTGAACAATCTCAGTAGTGGGTGAGACACATTTTGCAGAATCCTGC
  CAAACAAAGGAACTGAATAGGCTGTGGGCAAAGCAAATGAGGGAGAGTTAAGGAATGAAG
  TATTTTAAATATTAATAATTAATTCAGACACGGTACTGTATTTTCCGCAAAAGAAAATTA
  ACATTTAGTAACACACTAATGAATTTTATCTCCAAAGAGATTAGTGCACTGGCAAAGTAT
  TCGGATTACAGTGGAGAGCTGTGAACAGCAGATACCGAAAACACCCCAGCCTGGCAGATC
  CCAAGGTAACGATGGCCTTCACTGACCACTCCCTTTGCCAGAGGTCCAGAAAGAACTTGC
  AGCATGATCACCTGCCTGCTGCACTTNCAACTCTAGCAGNCAACTTCAAGGAGCCAAAGA
  GGAGTCCCCAGTGGGCAAGGNGAGCAGAGAGNAAAACGTGNTAANNTGTAACCTANAGAC
  AGTAAATGGGNATACATCCCATCCAATCCCAGAGATGTGGCAGTCCCCAAAGTAGTGTAG
  ATAAAAACTGGGCACACTCACTCCCCAAAATATATACTAAATTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012325
• ORF Size: 807 bp
• Insert Size: 2700
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_012325.1, NP_036457.1
• RefSeq Size: 2540
• RefSeq ORF: 807
• Locus ID: 22919
• Domains: CH, EB1
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]