HBS1L (NM_006620) Human Untagged Clone

CAT#: SC115985

HBS1L (untagged)-Human HBS1-like (S. cerevisiae) (HBS1L), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HBS1L
• Synonyms: EF-1a; eRF3c; ERFS; HBS1; HSPC276
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115985 sequence for NM_006620 edited (data generated by NextGen Sequencing)
  ATGGCCCGGCATCGGAATGTTCGAGGCTATAACTACGATGAAGATTTTGAAGATGATGAT
  CTCTACGGCCAGTCTGTAGAGGATGATTATTGTATTTCGCCGTCAACAGCTGCTCAGTTT
  ATTTATTCACGGCGTGACAAACCTTCCGTTGAGCCTGTGGAAGAATATGATTATGAAGAT
  CTGAAAGAATCTTCCAATTCTGTTTCAAACCATCAGCTCAGTGGATTTGATCAAGCTCGT
  CTTTATTCATGCCTTGATCACATGAGAGAGGTACTTGGAGATGCTGTGCCAGATGAAATA
  TTAATTGAAGCAGTTCTGAAGAACAAGTTTGATGTGCAGAAGGCTTTGTCAGGGGTTCTG
  GAACAAGATAGAGTGCAGAGTTTGAAGGACAAGAATGAGGCAACAGTATCTACAGGAAAG
  ATAGCAAAAGGAAAACCAGTAGATTCCCAGACATCGCGAAGTGAATCTGAAATTGTGCCA
  AAAGTTGCTAAAATGACTGTATCTGGAAAGAAGCAAACTATGGGATTTGAAGTGCCTGGA
  GTATCTTCTGAAGAAAATGGTCATAGTTTCCACACACCTCAAAAAGGACCGCCCATTGAA
  GATGCCATTGCTTCTTCCGATGTTCTTGAGACTGCTTCTAAATCTGCTAATCCACCCCAC
  ACGATTCAAGCATCAGAAGAGCAGAGTTCAACCCCAGCACCGGTGAAAAAGTCTGGCAAG
  CTGAGGCAGCAAATAGATGTGAAGGCGGAACTGGAGAAGCGGCAAGGAGGGAAGCAGCTA
  CTCAACTTAGTGGTCATTGGTCATGTTGATGCTGGGAAAAGTACTCTGATGGGCCATATG
  CTTTATCTTCTGGGTAATATAAACAAAAGAACTATGCATAAGTATGAACAGGAGTCTAAA
  AAGGCTGGCAAAGCTTCGTTTGCATATGCATGGGTCTTGGATGAAACTGGCGAAGAAAGG
  GAAAGGGGAGTAACCATGGATGTTGGTATGACAAAGTTTGAAACCACAACCAAAGTTATT
  ACATTAATGGATGCTCCAGGCCATAAGGACTTCATTCCAAATATGATTACAGGAGCAGCC
  CAGGCGGATGTAGCTGTTTTAGTTGTAGATGCCAGCAGGGGAGAGTTTGAAGCTGGATTT
  GAGACTGGAGGACAAACACGAGAGCATGGACTCTTGGTCCGTTCTCTGGGAGTGACGCAG
  CTTGCAGTTGCAGTTAATAAAATGGATCAGGTTAATTGGCAACAAGAAAGGTTTCAAGAG
  ATTACTGGAAAACTTGGGCACTTTCTTAAGCAAGCAGGTTTTAAGGAGAGTGATGTAGGT
  TTTATTCCTACAAGTGGTCTCAGTGGTGAAAATCTAATCACAAGATCTCAGTCAAGTGAA
  CTCACAAAATGGTATAAAGGACTATGTTTATTAGAACAAATTGATTCCTTTAAGCCTCCC
  CAGCGATCTATTGACAAACCTTTTAGATTATGTGTGTCCGATGTTTTCAAAGATCAAGGA
  TCTGGATTTTGCATAACTGGTAAAATAGAAGCTGGTTATATCCAAACTGGTGACCGACTA
  CTGGCAATGCCTCCTAATGAAACTTGTACCGTGAAAGGAATCACTCTGCATGATGAACCT
  GTCGACTGGGCGGCAGCAGGCGATCATGTTAGTCTTACTTTGGTTGGGATGGATATCATC
  AAAATCAATGTTGGCTGCATATTTTGTGGCCCCAAAGTACCCATTAAAGCTTGCACTCGT
  TTCAGAGCCCGAATCCTCATCTTTAATATTGAAATTCCTATCACTAAAGGATTTCCTGTG
  CTGTTACACTACCAAACTGTCAGTGAACCCGCCGTTATTAAACGATTGATTAGTGTCTTA
  AACAAAAGCACGGGTGAAGTCACAAAGAAAAAGCCTAAGTTTTTGACTAAAGGCCAGAAT
  GCATTGGTAGAGCTACAGACACAAAGACCAATAGCTCTTGAGCTATATAAAGACTTTAAA
  GAGCTGGGGAGGTTCATGCTACGTTACGGTGGTTCTACAATAGCTGCTGGTGTTGTCACT
  GAGATAAAAGAATGA
  
  Clone variation with respect to NM_006620.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006620 unedited
  TATACGACTCATATAGGCGGCCGCGAATTCGGCACGAGGCGCCTTATCAGTATCTAAGCG
  GAGTGTTTTGGAAGGAGTTAAGGGGCTGTGGCAAACGCCCTCTCCGCCGTCATGGCCCGG
  CATCGGAATGTTCGAGGCTATAACTACGATGAAGATTTTGAAGATGATGATCTCTACGGC
  CAGTCTGTAGAGGATGATTATTGTATTTCGCCGTCAACAGCTGCTCAGTTTATTTATTCA
  CGGCGTGACAAACCTTCCGTTGAGCCTGTGGAAGAATATGATTATGAAGATCTGAAAGAA
  TCTTCCAATTCTGTTTCAAACCATCAGCTCAGTGGATTTGATCAAGCTCGTCTTTATTCA
  TGCCTTGATCACATGAGAGAGGTACTTGGAGATGCTGTGCCAGATGAAATATTAATTGAA
  GCAGTTCTGAAGAACAAGTTTGATGTGCAGAAGGCTTTNGTCAGGGGTTCTGGAACAAGA
  TAGAGTGCAGAGTTTGAAGGACAAGAATGAGGCAACAGTATCTACAGGAAAGATAGCAAA
  AGGAAAACCAGTAGATTCCCAGACATCGCGAAGTGAATCTGAAATTGTGCCAAAAGTTGC
  TAAATGACTGTATCTGGAAAGAAGCAACTATGGGATTTTGAAGTGCCTGGAGTATCTTCT
  GAAGAAATGGTCATAGTTTCCACACCCTCANAAAGACCGCCATTNGAGATGCCATGCTCT
  TTCCGATGTTCTGGAGACTGCTCCTAATCTGCTAATCCACCCACACGATCAGCATAGAGA
  AANCGAGTTCACCCACCACGNGGAAAAAGTCTGCAGCTGAGACAAAAAAATTTTAAGGCG
  ACTGGAAACGCAGGAGGGACACACCCCCCTAGGGCTTTGGCCTTGGAGGGGGAAAAACTC
  TGGGGGCCTGCTTTTTTTTGGGAATAAAAAACTCCTATTTAAAGGGTTAAAGTGCGATTT
  TTTGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006620 unedited
  AGCTTTGGACCGGCGGCCGCAATCTAGGATCGAGNNNTTTTTTTTTTTTTTTTTTTATTA
  TGCTCAAACTAAGGCATTTTATTAGCTGGCTTTACAACTTAAATAATATCTTGGCTTTCA
  AAGGAACAGCTTCCACTAATTCCAAATTAAACTTTCACAAGTTTACTTGTTTGGGGAGGG
  ACATTCTTATGGTCACCACAAAATACTTTTATTATAACCTTCCCCAAATCTTTTCTTAGC
  ATTAACTGGAAAAAAAAAAAAAAAAAAGCTTAGGTCAAATATCAACTGCCTGAAAAACCC
  AATTAAGTTACTTTTCCTTAAAACATGTGCAGTATAATTGAATCAAAAGAGAAAACTGCA
  AATACATTGTGCTTTGGCCAGAAGTAGAGTTCATTTCATGATGATTCAGTATCTTCAGAT
  ACTATTTTTGACACTTGCCATAAATCTTAGCAAAGTAAATCCATTTATTAACGTTTCAAA
  GGCAAAGTTGTTTTTAACATTAAACTTTCTTTGCCAGTTGGCAACTTAAAATTTTTGCAG
  AGGTGATTATTAATACTTCTTTGCAGCTAATTTTAGCTTTAATTTTTCTCTCTCATCTAA
  AAACATATCAATTGCACATTGTTCCTTTGACTTAATAACTGCATTCTTGAAACAGAGGTT
  AGCTATTTCACTGTATCCAGAAACGTGGTAGAAATTCTGACCCATCATTCTTTTATCTCA
  GTGACAACACCAGCAGCTATTGTAGAACCACCGTACGTAGCATGAACCTCCCCAGCTCTT
  TAAGTCTTTATATAGCTCAAGACTATTGGTCTTTGTGTCTGTAGCTCTACCATGCATTCT
  GGCCTTAGTCAAAAACTTAAGCTTTTNCTTTGTGACTTCACCCGTGCTTTGTTTAAGACA
  CTATCATCGTTTATAACCGCCGGTCACTGACAGTTGGGAGTGAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006620
• ORF Size: 2055 bp
• Insert Size: 2770
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006620.2, NP_006611.1
• RefSeq Size: 7163
• RefSeq ORF: 2055
• Locus ID: 10767
• Domains: GTP_EFTU, GTP_EFTU_D3, GTP_EFTU_D2
• Gene Summary: This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, May 2009]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).