EMAP II (AIMP1) (NM_004757) Human Untagged Clone

CAT#: SC117158

AIMP1 (untagged)-Human aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 (AIMP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AIMP1
• Synonyms: EMAP2; EMAPII; HLD3; p43; SCYE1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117158 sequence for NM_004757 edited (data generated by NextGen Sequencing)
  ATGGCAAATAATGATGCTGTTCTGAAGAGACTGGAGCAGAAGGGTGCAGAGGCAGATCAA
  ATCATTGAATATCTTAAGCAGCAAGTTTCTCTACTTAAGGAGAAAGCAATTTTGCAGGCA
  ACTTTGAGGGAAGAGAAGAAACTTCGAGTTGAAAATGCTAAACTGAAGAAAGAAATTGAA
  GAACTGAAACAAGAGCTAATTCAGGCAGAAATTCAAAATGGAGTGAAGCAAATACCATTT
  CCATCTGGTACTCCACTGCACGCTAATTCTATGGTTTCTGAAAATGTGATACAGTCTACA
  GCAGTAACAACCGTATCTTCTGGTACCAAAGAACAGATAAAAGGAGGAACAGGAGACGAA
  AAGAAAGCGAAAGAGAAAATTGAAAAGAAAGGAGAGAAGAAGGAGAAAAAACAGCAATCA
  ATAGCTGGAAGTGCCGACTCTAAGCCAATAGATGTTTCCCGTCTGGATCTTCGAATTGGT
  TGCATCATAACTGCTAGAAAACACCCTGATGCAGATTCTTTGTATGTGGAAGAAGTAGAT
  GTCGGAGAAATAGCCCCAAGGACAGTTGTCAGTGGCCTGGTGAATCATGTTCCTCTTGAA
  CAGATGCAAAATCGGATGGTGATTTTACTTTGTAACCTGAAACCTGCAAAGATGAGGGGA
  GTATTATCTCAAGCAATGGTCATGTGTGCTAGTTCACCAGAGAAAATTGAAATCTTGGCT
  CCTCCAAATGGGTCTGTTCCTGGAGACAGAATTACTTTTGATGCTTTCCCAGGAGAGCCT
  GACAAGGAGCTGAATCCTAAGAAGAAGATTTGGGAGCAGATCCAGCCTGATCTTCACACT
  AATGATGAGTGTGTGGCTACATACAAAGGAGTTCCCTTTGAGGTGAAAGGGAAGGGAGTA
  TGTAGGGCTCAAACCATGAGCAACAGTGGAATCAAATAA
  
  Clone variation with respect to NM_004757.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004757 unedited
  TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCTTCCTGCTGTGGCT
  GTCTCGGAACCCGTGGTCCTCCGCTTCATGATTTTCTGCCGTCTCTTGGCAAAAATGGCA
  AATAATGATGCTGTTCTGAAGAGACTGGAGCAGAAGGGTGCAGAGGCAGATCAAATCATT
  GAATATCTTAAGCAGCAAGTTTCTCTACTTAAGGAGAAAGCAATTTTGCAGGCAACTTTG
  AGGGAAGAGAAGAAACTTCGAGTTGAAAATGCTAAACTGAAGAAAGAAATTGAAGAACTG
  AAACAAGAGCTAATTCAGGCAGAAATTCAAAATGGAGTGAAGCAAATACCATTTCCATCT
  GGTACTCCACTGCACGCTAATTCTATGGTTTCTGAAAATGTGATACAGTCTACAGCAGTA
  ACAACCGTATCTTCTGGTACCAAAGAACAGATAAAAGGAGGAACAGGAGACGAAAAGAAA
  GCGAAAGAGAAAATTGAAAAGAAAGGAGAGAAGAAGGAGAAAAAACAGCAATCAATAGCT
  GGAAGTGCCGACTCTAAGCCAATAGATGTTTCCCGTCTGGATCTTCGAATTGGTTGCATC
  ATAACTGCTAGAAAACACCCTGATGCAGATTCTTTGTATGTGGAAGAAGTAGATGTCGGA
  GAAATAGCCCCAAGGACAGTTGTCAGTGGCCTGGTGAATATTGTTCTCTTGAACAGATGC
  AAATCGGATGGTGATTTTACTTTGTAACCCTGAACCTGCAAGATGAGGGGAGTATTATCT
  CAAGCATGGTCATGTGTGCTAATTCACAGAGAAATTGAATCTTGCTCCTCAAAGGGTCTG
  TCCTGGAGACAAATACTTTTGATGCTTTCCAGGAGAGCTGACAGGAGCTGAATCTAGAAG
  AGATTGGGACCGACCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004757
• ORF Size: 939 bp
• Insert Size: 2600
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_004757.2, NP_004748.2
• RefSeq Size: 1764
• RefSeq ORF: 939
• Locus ID: 9255
• Domains: tRNA_bind
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the shorter isoform (a). Both variants 1 and 2 encode the same isoform.