MX1 (NM_002462) Human Untagged Clone

CAT#: SC118603

MX1 (untagged)-Human myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) (MX1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MX1
• Synonyms: IFI-78K; IFI78; MX; MxA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118603 sequence for NM_002462 edited (data generated by NextGen Sequencing)
  ATGGTTGTTTCCGAAGTGGACATCGCAAAAGCTGATCCAGCTGCTGCATCCCACCCTCTA
  TTACTGAATGGAGATGCTACTGTGGCCCAGAAAAATCCAGGCTCGGTGGCTGAGAACAAC
  CTGTGCAGCCAGTATGAGGAGAAGGTGCGCCCCTGCATCGACCTCATTGACTCCCTGCGG
  GCTCTAGGTGTGGAGCAGGACCTGGCCCTGCCAGCCATCGCCGTCATCGGGGACCAGAGC
  TCGGGCAAGAGCTCCGTGTTGGAGGCACTGTCAGGAGTTGCCCTTCCCAGAGGCAGCGGG
  ATCGTGACCAGATGCCCGCTGGTGCTGAAACTGAAGAAACTTGTGAACGAAGATAAGTGG
  AGAGGCAAGGTCAGTTACCAGGACTACGAGATTGAGATTTCGGATGCTTCAGAGGTAGAA
  AAGGAAATTAATAAAGCCCAGAATGCCATCGCCGGGGAAGGAATGGGAATCAGTCATGAG
  CTAATCACCCTGGAGATCAGCTCCCGAGATGTCCCGGATCTGACTCTAATAGACCTTCCT
  GGCATAACCAGAGTGGCTGTGGGCAATCAGCCTGCTGACATTGGGTATAAGATCAAGACA
  CTCATCAAGAAGTACATCCAGAGGCAGGAGACAATCAGCCTGGTGGTGGTCCCCAGTAAT
  GTGGACATTGCCACCACAGAGGCTCTCAGCATGGCCCAGGAGGTGGACCCCGAGGGAGAC
  AGGACCATCGGAATCTTGACGAAGCCTGATCTGGTGGACAAAGGAACTGAAGACAAGGTT
  GTGGACGTGGTGCGGAACCTCGTGTTCCACCTGAAGAAGGGTTACATGATTGTCAAGTGC
  CGGGGCCAGCAGGAGATCCAGGACCAGCTGAGCCTGTCCGAAGCCCTGCAGAGAGAGAAG
  ATCTTCTTTGAGAACCACCCATATTTCAGGGATCTGCTGGAGGAAGGAAAGGCCACGGTT
  CCCTGCCTGGCAGAAAAACTTACCAGCGAGCTCATCACACATATCTGTAAATCTCTGCCC
  CTGTTAGAAAATCAAATCAAGGAGACTCACCAGAGAATAACAGAGGAGCTACAAAAGTAT
  GGTGTCGACATACCGGAAGACGAAAATGAAAAAATGTTCTTCCTGATAGATAAAATTAAT
  GCCTTTAATCAGGACATCACTGCTCTCATGCAAGGAGAGGAAACTGTAGGGGAGGAAGAC
  ATTCGGCTGTTTACCAGACTCCGACACGAGTTCCACAAATGGAGTACAATAATTGAAAAC
  AATTTTCAAGAAGGCCATAAAATTTTGAGTAGAAAAATCCAGAAATTTGAAAATCAGTAT
  CGTGGTAGAGAGCTGCCAGGCTTTGTGAATTACAGGACATTTGAGACAATCGTGAAACAG
  CAAATCAAGGCACTGGAAGAGCCGGCTGTGGATATGCTACACACCGTGACGGATATGGTC
  CGGCTTGCTTTCACAGATGTTTCGATAAAAAATTTTGAAGAGTTTTTTAACCTCCACAGA
  ACCGCCAAGTCCAAAATTGAAGACATTAGAGCAGAACAAGAGAGAGAAGGTGAGAAGCTG
  ATCCGCCTCCACTTCCAGATGGAACAGATTGTCTACTGCCAGGACCAGGTATACAGGGGT
  GCATTGCAGAAGGTCAGAGAGAAGGAGCTGGAAGAAGAAAAGAAGAAGAAATCCTGGGAT
  TTTGGGGCTTTCCAGTCCAGCTCGGCAACAGACTCTTCCATGGAGGAGATCTTTCAGCAC
  CTGATGGCCTATCACCAGGAGGCCAGCAAGCGCATCTCCAGCCACATCCCTTTGATCATC
  CAGTTCTTCATGCTCCAGACGTACGGCCAGCAGCTTCAGAAGGCCATGCTGCAGCTCCTG
  CAGGACAAGGACACCTACAGCTGGCTCCTGAAGGAGCGGAGCGACACCAGCGACAAGCGG
  AAGTTCCTGAAGGAGCGGCTTGCACGGCTGACGCAGGCTCGGCGCCGGCTTGCCCAGTTC
  CCCGGTTAA
  
  Clone variation with respect to NM_002462.3
  669 c=>t;1135 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002462 unedited
  GAAGACCAATTCGCACGAGGCGCAGTTGTTTGNCCGGNAATCCCAGTGTCACGGTGGCAC
  ACTCCTCCCTCGCGCCCTTGCCGCCCACCTGCTCACCCAGCTCAGGGGCTTTGGAATTCT
  GTGGCCACACTGCGAGGAGATCGGTTCTGGGTCGGAGGCTACAGGAAGACTCCCACTCTC
  GTAACTGGAGTGAATAACGCCGCTCATCCAGCCACCATTCCAAGGAGGTGCAGGAGAACA
  GCTCTGTGATACCATTTAACTTGTTGACATTACTTTTATTTGAAGGAACGTATATTAGAG
  GCATCTGCTTTATTTTAAGCTTACTTTGCAAAGAAGGAAGATGGTTGTTTCCGAAGTGGA
  CATCGCAAAAGCTGATCCAGCTGCTGCATCCCACCCTCTATTACTGAATGGAGATGCTAC
  TGTGGCCCAGAAAAATCCAGGCTCGGTGGCTGAGAACAACCTGTGCAGCCAGTATGAGGA
  GAAGGTGCGCCCCTGCATCGACCTCATTGACTCCCTGCGGGCTCTAGGTGTGGAGCAGGA
  CCTGGCCCTGCCAGCCATCGCCGTCATCGGGGACCAGAGCTCGGGCAAGAGCTCCGTGTT
  GGAGGCACTGTCAGGAGTTGCCCTTCCCAGAAGCAGCGGGATCGTGACCAGATGCCCGCT
  GGTGCTGNAACTGAAGAACTTGTGAACGAAGTAAGTGGAAAGGCAGGTCAGTTACCAGGA
  CTACGAGATTGAGATTTCGGATGCTTCAGAGGTAGAAAAGGAAATTAAATAAGCCCACAA
  TGCCATCGCCGGGGAAAGAATGGGAATCAGTCCTGAACTAATCACCCTGGAGATCACCTC
  CGAGATGTCCCCGATACTGACTCTAAAAACTTTCTGGGATAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002462 unedited
  AATCNTTGCCCGCGGCCGCAATTCACATNCGGTTTTTTTTTTTTTTTTTTCTGCTACAAA
  TGACTCATTACAGACAGAGGAGACAGGGGTGGGACAGGACGCACACACACGGCACTCATG
  CTCCTAAAACACTGGGTTTGTGAAGGGACATTATAAAAATGAGGAAATAAGCTGTGATGT
  TCAGCATGTGTCAGTTTCTAGGAATACAGAGAAGGGTTTTATTTGCAAGGTGGAGCGATT
  CTGAGGGCTGAAAATCCCTTTCTTTTTCGAAGACAGCATCCTTCAATCCCGCCAGCTCAT
  GTGCATCTGAGGGTGGGGCTCTGTCTTCATGCTAGAAACCAAACTGCTCTCACAGCTTCC
  TGCTAAATCACCACGGCTAACGGATAAGCAGAGACGGACTATCCAGTCTGACTACTGAGC
  ACTCAAGTCGTCAGTCCAGTGGCTACCCGGGAACGGGGGCAGACAGCGTGCGTGCACGTC
  TACGGGGCTGGACAGAGTGTGGTTAACCGGGGAACTGGGCAAGCCGGCGCCGACCCTGCC
  TCAGTCGTGCAAGCCGCTCCTTCAGGAACTCCCGCTTGTCGCTGGTGTCGCTCCCCTCTT
  TCAGACCCAGCTGTAGGTGTCCTTGTCCTGCAGGAGCTGCAGTATGCCCTTCTGAACCTG
  CTGGCCGCACCCTCGGAGCATGAAAACCTGTATGATCAAAGCGACGTGCTTCGAAATCCC
  CTTTGCTGGCCTCCTGCGGATAGGCCCTACGGTGCTGCAAGATCCCCTCCCCGGCAAAAC
  CTGTTGCCGAGCTGGACTGGAAACGCCCCAAACCCCAGGAATTCTTTTTCCTTCTCTTCT
  TACCACTTCTTCCTCTCTGACCTTTTCGAATGACCCCCTCGTATCCCCGGCCTCGGAATA
  AACAACCCGCCCATTTGAAAAGGCGGCCCGCCCCCTTTTTCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002462
• Insert Size: 2380 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002462.2, NP_002453.1
• RefSeq Size: 2787 bp
• RefSeq ORF: 1989 bp
• Locus ID: 4599
• Cytogenetics: 21q22.3
• Domains: dynamin_2, dynamin, GED
• Protein Families: Druggable Genome
• Gene Summary: 'This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]'
  Transcript Variant: This variant (2, also known as T1) lacks three exons and contains an alternate terminal exon in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same isoform (a).