EXT2 (NM_000401) Human Untagged Clone

CAT#: SC119905

EXT2 (untagged)-Human exostosin 2 (EXT2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EXT2
• Synonyms: SOTV; SSMS
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_000401, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCCTGCGCCTCAGGGTCCGGTGGTGGCCTGCGGCATCCCTTGCGGTGCCAGAAGCCGTGGGACGAGG
  AGTGTGAGGAAGAGGCTGTCTGTGTCATTATGTGTGCGTCGGTCAAGTATAATATCCGGGGTCCTGCCCT
  CATCCCAAGAATGAAGACCAAGCACCGAATCTACTATATCACCCTCTTCTCCATTGTCCTCCTGGGCCTC
  ATTGCCACTGGCATGTTTCAGTTTTGGCCCCATTCTATCGAGTCCTCAAATGACTGGAATGTAGAGAAGC
  GCAGCATCCGTGATGTGCCGGTTGTTAGGCTGCCAGCCGACAGTCCCATCCCAGAGCGGGGGGATCTCAG
  TTGCAGAATGCACACGTGTTTTGATGTCTATCGCTGTGGCTTCAACCCAAAGAACAAAATCAAGGTGTAT
  ATCTATGCTCTGAAAAAGTACGTGGATGACTTTGGCGTCTCTGTCAGCAACACCATCTCCCGGGAGTATA
  ATGAACTGCTCATGGCCATCTCAGACAGTGACTACTACACTGATGACATCAACCGGGCCTGTCTGTTTGT
  TCCCTCCATCGATGTGCTTAACCAGAACACACTGCGCATCAAGGAGACAGCACAAGCGATGGCCCAGCTC
  TCTAGGTGGGATCGAGGTACGAATCACCTGTTGTTCAACATGTTGCCTGGAGGTCCCCCAGATTATAACA
  CAGCCCTGGATGTCCCCAGAGACAGGGCCCTGTTGGCTGGTGGCGGCTTTTCTACGTGGACTTACCGGCA
  AGGCTACGATGTCAGCATTCCTGTCTATAGTCCACTGTCAGCTGAGGTGGATCTTCCAGAGAAAGGACCA
  GGTCCACGGCAATACTTCCTCCTGTCATCTCAGGTGGGTCTCCATCCTGAGTACAGAGAGGACCTAGAAG
  CCCTCCAGGTCAAACATGGAGAGTCAGTGTTAGTACTCGATAAATGCACCAACCTCTCAGAGGGTGTCCT
  TTCTGTCCGTAAGCGCTGCCACAAGCACCAGGTCTTCGATTACCCACAGGTGCTACAGGAGGCTACTTTC
  TGTGTGGTTCTTCGTGGAGCTCGGCTGGGCCAGGCAGTATTGAGCGATGTGTTACAAGCTGGCTGTGTCC
  CGGTTGTCATTGCAGACTCCTATATTTTGCCTTTCTCTGAAGTTCTTGACTGGAAGAGAGCATCTGTGGT
  TGTACCAGAAGAAAAGATGTCAGATGTGTACAGTATTTTGCAGAGCATCCCCCAAAGACAGATTGAAGAA
  ATGCAGAGACAGGCCCGGTGGTTCTGGGAAGCGTACTTCCAGTCAATTAAAGCCATTGCCCTGGCCACCC
  TGCAGATTATCAATGACCGGATCTATCCATATGCTGCCATCTCCTATGAAGAATGGAATGACCCTCCTGC
  TGTGAAGTGGGGCAGCGTGAGCAATCCACTCTTCCTCCCGCTGATCCCACCACAGTCTCAAGGGTTCACC
  GCCATAGTCCTCACCTACGACCGAGTAGAGAGCCTCTTCCGGGTCATCACTGAAGTGTCCAAGGTGCCCA
  GTCTATCCAAACTACTTGTCGTCTGGAATAATCAGAATAAAAACCCTCCAGAAGATTCTCTCTGGCCCAA
  AATCCGGGTTCCATTAAAAGTTGTGAGGACTGCTGAAAACAAGTTAAGTAACCGTTTCTTCCCTTATGAT
  GAAATCGAGACAGAAGCTGTTCTGGCCATTGATGATGATATCATTATGCTGACCTCTGACGAGCTGCAAT
  TTGGTTATGAGGTCTGGCGGGAATTTCCTGACCGGTTGGTGGGTTACCCGGGTCGTCTGCATCTCTGGGA
  CCATGAGATGAATAAGTGGAAGTATGAGTCTGAGTGGACGAATGAAGTGTCCATGGTGCTCACTGGGGCA
  GCTTTTTATCACAAGTATTTTAATTACCTGTATACCTACAAAATGCCTGGGGATATCAAGAACTGGGTAG
  ATGCTCATATGAACTGTGAAGATATTGCCATGAACTTCCTGGTGGCCAACGTCACGGGAAAAGCAGTTAT
  CAAGGTAACCCCACGAAAGAAATTCAAGTGTCCTGAGTGCACAGCCATAGATGGGCTTTCACTAGACCAA
  ACACACATGGTGGAGAGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGG
  TGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAA
  CATTGGCAGCTTATGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000401 unedited
  GTCAGATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTGGCA
  GTGGCGGCTGGCGATTCGGACCGATCCGACCTGGGCGGAGGTGGCCCGCGCCCCGCGGCA
  TGAGCCGGTGACCAAGCTGGGGGCCGAGCGGGAGGCAGCCGTGGCCGAGGAGTGTGAGGA
  AGAGGCTGTCTGTGTCATTATGTGTGCGTCGGTCAAGTATAATATCCGGGGTCCTGCCCT
  CATCCCAAGAATGAAGACCAAGCACCGAATCTACTATATCACCCTCTTCTCCATTGTCCT
  CCTGGGCCTCATTGCCACTGGCATGTTTCAGTTTTGGCCCCATTCTATCGAGTCCTCAAA
  TGACTGGAATGTAGAGAAGCGCAGCATCCGTGATGTGCCGGTTGTTAGGCTGCCAGCCGA
  CAGTCCCATCCCAGAGCGGGGGGATCTCAGTTGCAGAATGCACACGTGTTTTGATGTCTA
  TCGCTGTGGCTTCAACCCAAAGAACAAAATCAAGGTGTATATCTATGCTCTGAAAAAGTA
  CGTGGATGACTTTGGCGTCTCTGTCAGCAACACCATCTNCCGGGAGTATAATGAACTGCT
  CATGGCCATCTCAGACAGTGACTACTACACTGATGACATCAAACCGGCCTGTCTGTTTGT
  TCCCTCCATCGATGTGCCTTACCCAGAACACACTGCGCATCAAAGAGACAGCACAAGCGA
  TGGCCCAGCTCTCTTAGTGGGATCGAGGTACGAATCACCTGTTGGTCACATGTTGCCTGG
  AGGTCCCCCAAATTATACACAGCCCTTGGATGTTCCCACAGACCGGTCCCCTGTTGGCTG
  GTGGCGGCTTTTCTACTTGGACTTACCCGCATGGTTCACATGTCACCATCCCTTGTTTAT
  ATCCACTGTCACCTGAAGGGGATCTTTCCAAAATAGAACAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000401 unedited
  GCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAAGGAATAAAAAATAATTTTAA
  TCATATCAAAAAGCCAAACCAAAGAGGAATAGCTCATGGAACTGACAGGATCCTGACTCA
  GCGGCTGGTGCTCTTCCTGTGCACAAGCCCAGCACTCCAGGTCCCAAGGCATTTATCAAA
  TCCCACCAAGATGTTTGGCTTTTGCACCGAATTCTGGGTTTGGTTCCCTGAAAGAACTCA
  TTGATGTAAATAACTAAAAGTGAGGTCTGGGTACCCTTTACATGATTCCCCAGACCTCAA
  ATGGGCTAACACGCTTCTCTTCTCCAGCAGTCTTCCTGTCCGTGAAGTTTCCTTCCAGAT
  TGTTACATGGAACTGAAAACAAAGGGAGCCTCAGCTGGATTTAAATCTGGAGCATGCCAC
  AAAGTCTTCCACTTGGCATTTTCGAGAAGAACCCATCAGAGATCATAAGAAATACAAGGA
  ACAGAGGTTGCATAGCTCGAGGCGCTTGGATATTCATTCTAGGTTCTTGTCCTTGAGAAA
  GTGGGTTAGGTGGGTGCATGCCAAGATCCAAGTAGTCAACCCTCCACCCTTAACCTACTA
  CTCTGACATTAAAGAGCTGGGAGGCCTTGTTCTCTAGCTCTGACCCAGCCTCACATTCAG
  ACCTCCAACATAGACACGTTTCATAAGCCGCCAATGTTGGGGCAACCTTCTCACCTTCTC
  AGGATAGCACTCTTTGACAAGGACAGGGTCAGCCCGGCGGTCACCCCCTTGAGAGGGCTG
  GGTCCCAAAACTGAAACAAACTGGNTGTCGACCCTGACCTCCCCACCTGCGGGGTTGGCC
  TAACGAAGCCCACCTTTGCCGGCCACTCAGACACTGGAACTTCTTCAGGGGCTACCTGGA
  TACCGCTCTTCCCGGAGGTGGGCACCAGGATGTTCTGGCAATTCTTTCCGGCCATAGAAA
  CTTCACACTCTTGCATACCCAGCCTTCGCGGGATCAGAGATCAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000401
• Insert Size: 3090 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000401.2, NP_000392.2
• RefSeq Size: 3804 bp
• RefSeq ORF: 2196 bp
• Locus ID: 2132
• Cytogenetics: 11p11.2
• Domains: Exostosin
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Heparan sulfate biosynthesis, Metabolic pathways
• Gene Summary: 'This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) encodes the longer isoform (1).